Cubs vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 8

Odds updated as of 8:11 p.m.

The Chicago Cubs will take on the St. Louis Cardinals in MLB action on Friday.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Cubs vs Cardinals Game Info

• Chicago Cubs (66-48) vs. St. Louis Cardinals (58-58)
• Date: Friday, August 8, 2025
• Time: 8:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: MLB Network, FDSMW, and MARQ

Cubs vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-166) | STL: (+140)
• Spread: CHC: -1.5 (+104) | STL: +1.5 (-125)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Cubs vs Cardinals Probable Starting Pitchers

Probable Pitchers: Matthew Boyd (Cubs) - 11-4, 2.34 ERA vs Michael McGreevy (Cardinals) - 3-2, 5.08 ERA

The probable starters are Matthew Boyd (11-4) for the Cubs and Michael McGreevy (3-2) for the Cardinals. Boyd's team is 9-12-0 against the spread this season in his starts. Boyd's team has been victorious in 66.7% of the games he's started as the moneyline favorite with a record of 10-5. The Cardinals have a 4-2-0 ATS record in McGreevy's six starts with a set spread. The Cardinals are 2-1 in McGreevy's three starts this season that they were the underdog on the moneyline.

Cubs vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (54.3%)

Cubs vs Cardinals Moneyline

• Chicago is the favorite, -166 on the moneyline, while St. Louis is a +140 underdog despite being at home.

Cubs vs Cardinals Spread

• The Cubs are at the Cardinals and are favored by 1.5 runs (+104 to cover) on the runline. St. Louis is -125 to cover.

Cubs vs Cardinals Over/Under

• Cubs versus Cardinals, on Aug. 8, has an over/under of 8.5, with the over being -105 and the under -115.

Bet on Chicago Cubs vs. St. Louis Cardinals on FanDuel today!

Cubs vs Cardinals Betting Trends

• The Cubs have come away with 50 wins in the 75 contests they have been listed as the favorites in this season.
• This season Chicago has been victorious 19 times in 28 chances when named as a favorite of at least -166 on the moneyline.
• The Cubs and their opponents have gone over in 55 of their 111 games with a total set by sportsbooks this season.
• The Cubs are 53-58-0 against the spread in their 111 games with a line set by sportsbooks this season.
• The Cardinals have been the underdog on the moneyline 60 total times this season. They've gone 30-30 in those games.
• St. Louis has a 5-9 record (winning only 35.7% of its games) when it has played as a moneyline underdog of +140 or longer.
• The Cardinals have played in 113 games with a set over/under, and have combined with their opponents to go over the total 57 times (57-51-5).
• The Cardinals have collected a 59-54-0 record against the spread this season (covering 52.2% of the time).

Cubs Player Leaders

• Kyle Tucker leads Chicago in OBP (.384) this season, fueled by 111 hits. He has a .271 batting average and a slugging percentage of .474.
• Among all qualifying batters in MLB, he ranks 51st in batting average, sixth in on-base percentage, and 36th in slugging.
• Pete Crow-Armstrong leads Chicago with 115 hits. He is batting .264 this season and has 62 extra-base hits. He's also slugging .539 with an on-base percentage of .301.
• Among qualifying hitters, his batting average ranks him 66th, his on-base percentage 134th, and his slugging percentage ninth.
• Seiya Suzuki has 107 hits this season and has a slash line of .251/.318/.513.
• Nico Hoerner leads Chicago in slugging percentage (.380) thanks to 26 extra-base hits.

Cardinals Player Leaders

• Brendan Donovan has a .351 on-base percentage and a .405 slugging percentage, both team-best numbers for the Cardinals. He's batting .280.
• Including all the qualified hitters in the majors, his batting average is 29th, his on-base percentage ranks 44th, and he is 100th in slugging.
• Alec Burleson is batting .279 with 19 doubles, 14 home runs and 30 walks. He's slugging .450 with an on-base percentage of .333.
• He is currently 31st in batting average, 67th in on-base percentage and 66th in slugging percentage among all qualifying hitters.
• Willson Contreras paces the Cardinals with 103 hits.
• Masyn Winn is batting .270 with 24 doubles, eight home runs and 29 walks.

Cubs vs Cardinals Head to Head

• 7/5/2025: 8-6 STL (Favorite: Cubs, Spread: -1.5, Total: 11, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 7/4/2025: 11-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/26/2025: 3-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/25/2025: 8-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/24/2025: 8-7 STL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/23/2025: 8-2 STL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/4/2024: 6-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 8/3/2024: 5-4 STL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/2/2024: 6-3 CHC (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/1/2024: 5-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)

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