Cubs vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 8

Odds updated as of 6:12 a.m.

The Chicago Cubs will take on the St. Louis Cardinals in MLB action on Friday.

We've got you covered, in terms of the most important info regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Cardinals Game Info

• Chicago Cubs (66-48) vs. St. Louis Cardinals (58-58)
• Date: Friday, August 8, 2025
• Time: 8:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: MLB Network, FDSMW, and MARQ

Cubs vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-156) | STL: (+132)
• Spread: CHC: -1.5 (+105) | STL: +1.5 (-126)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Cubs vs Cardinals Probable Starting Pitchers

Probable Pitchers: Matthew Boyd (Cubs) - 11-4, 2.34 ERA vs Michael McGreevy (Cardinals) - 3-2, 5.08 ERA

The Cubs will call on Matthew Boyd (11-4) versus the Cardinals and Michael McGreevy (3-2). Boyd and his team have a record of 9-12-0 against the spread when he starts. Boyd's team has won 66.7% of his starts when they are favored on the moneyline (10-5). When McGreevy starts, the Cardinals have gone 4-2-0 against the spread. The Cardinals have been the moneyline underdog in three of McGreevy's starts this season, and they went 2-1 in those games.

Cubs vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (54.2%)

Cubs vs Cardinals Moneyline

• St. Louis is the underdog, +132 on the moneyline, while Chicago is a -156 favorite despite being on the road.

Cubs vs Cardinals Spread

• The Cubs are favored by 1.5 runs on the road against the Cardinals. The Cubs are +105 to cover the spread, while the Cardinals are -126.

Cubs vs Cardinals Over/Under

• The over/under for Cubs-Cardinals on Aug. 8 is 8.5. The over is -105, and the under is -115.

Bet on Chicago Cubs vs. St. Louis Cardinals on FanDuel today!

Cubs vs Cardinals Betting Trends

• The Cubs have been favorites in 75 games this season and have come away with the win 50 times (66.7%) in those contests.
• This season Chicago has come away with a win 25 times in 36 chances when named as a favorite of at least -156 on the moneyline.
• The Cubs' games have gone over the total in 55 of their 111 opportunities.
• The Cubs have an against the spread record of 53-58-0 in 111 games with a line this season.
• The Cardinals have won 30 of the 60 games they were listed as the moneyline underdog this season (50%).
• When playing as a moneyline underdog with odds of +132 or longer, St. Louis has a record of 7-12 (36.8%).
• The Cardinals have had an over/under set by bookmakers 113 times, and have combined with opponents to go over the total in 57 of those games (57-51-5).
• The Cardinals have covered 52.2% of their games this season, going 59-54-0 against the spread.

Cubs Player Leaders

• Kyle Tucker leads Chicago with an OBP of .384 this season while batting .271 with 75 walks and 75 runs scored. He has a slugging percentage of .474.
• Among qualifying hitters in the majors, he is 51st in batting average, sixth in on-base percentage, and 36th in slugging.
• Pete Crow-Armstrong leads Chicago with 115 hits. He is batting .264 this season and has 62 extra-base hits. He's also slugging .539 with an on-base percentage of .301.
• Among qualifying hitters, he ranks 66th in batting average, 134th in on-base percentage and ninth in slugging percentage.
• Seiya Suzuki is batting .251 with a .513 slugging percentage and 84 RBI this year.
• Nico Hoerner leads Chicago with a slugging percentage of .380, fueled by 26 extra-base hits.

Cardinals Player Leaders

• Brendan Donovan has a team-high OBP (.351) and slugging percentage (.405). He's batting .280.
• Including all the qualified players in MLB, his batting average is 29th, his on-base percentage ranks 44th, and he is 100th in slugging.
• Alec Burleson has 19 doubles, 14 home runs and 30 walks while batting .279. He's slugging .450 with an on-base percentage of .333.
• Including all qualifying players, he is 31st in batting average, 67th in on-base percentage and 66th in slugging percentage.
• Willson Contreras has collected 103 hits, a team-high for the Cardinals.
• Masyn Winn is hitting .270 with 24 doubles, eight home runs and 29 walks.

Cubs vs Cardinals Head to Head

• 7/5/2025: 8-6 STL (Favorite: Cubs, Spread: -1.5, Total: 11, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 7/4/2025: 11-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/26/2025: 3-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/25/2025: 8-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/24/2025: 8-7 STL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/23/2025: 8-2 STL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/4/2024: 6-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 8/3/2024: 5-4 STL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/2/2024: 6-3 CHC (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/1/2024: 5-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)

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