Cubs vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 10

Odds updated as of 6:13 p.m.

The MLB's Sunday slate includes the Chicago Cubs taking on the St. Louis Cardinals.

All the information you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Cubs vs Cardinals Game Info

• Chicago Cubs (67-49) vs. St. Louis Cardinals (59-59)
• Date: Sunday, August 10, 2025
• Time: 7:10 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: ESPN

Cubs vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-126) | STL: (+108)
• Spread: CHC: -1.5 (+136) | STL: +1.5 (-164)
• Total: 7.5 -- Over: (-110) | Under: (-110)

Cubs vs Cardinals Probable Starting Pitchers

Probable Pitchers: Shota Imanaga (Cubs) - 8-4, 3.12 ERA vs Sonny Gray (Cardinals) - 10-5, 4.21 ERA

The probable pitchers are Shota Imanaga (8-4) for the Cubs and Sonny Gray (10-5) for the Cardinals. When Imanaga starts, his team is 8-8-0 against the spread this season. Imanaga's team has a record of 6-4 this season when he starts and they are the favorite on the moneyline. The Cardinals have gone 12-10-0 ATS in Gray's 22 starts that had a set spread. The Cardinals have been the moneyline underdog in seven of Gray's starts this season, and they went 5-2 in those matchups.

Cubs vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (53.4%)

Cubs vs Cardinals Moneyline

• Chicago is a -126 favorite on the moneyline, while St. Louis is a +108 underdog at home.

Cubs vs Cardinals Spread

• The Cardinals are +1.5 on the spread (-164 to cover), and Chicago is +136 to cover the runline.

Cubs vs Cardinals Over/Under

• Cubs versus Cardinals, on Aug. 10, has an over/under of 7.5, with the over being -110 and the under -110.

Bet on Chicago Cubs vs. St. Louis Cardinals on FanDuel today!

Cubs vs Cardinals Betting Trends

• The Cubs have won in 51, or 66.2%, of the 77 contests they have been named as odds-on favorites in this year.
• This season Chicago has come away with a win 43 times in 63 chances when named as a favorite of at least -126 on the moneyline.
• The Cubs and their opponents have gone over in 56 of their 113 games with a total set by sportsbooks this season.
• The Cubs have posted a record of 54-59-0 against the spread this season.
• The Cardinals have won 50% of the games this season they were the moneyline underdog (31-31).
• St. Louis is 16-22 (winning 42.1% of its games) when playing as a moneyline underdog of +108 or longer.
• In the 115 games oddsmakers have set an over/under for the Cardinals, they have combined with opponents to go over the total 58 times (58-52-5).
• The Cardinals have a 60-55-0 record against the spread this season (covering 52.2% of the time).

Cubs Player Leaders

• Kyle Tucker leads Chicago in OBP (.386) this season, fueled by 113 hits. He has a .272 batting average and a slugging percentage of .471.
• Among qualifying batters in the majors, he is 48th in batting average, fifth in on-base percentage, and 40th in slugging.
• Tucker hopes to build on a two-game hitting streak in this matchup. In his last five games he is batting .235 with two walks and an RBI.
• Pete Crow-Armstrong leads Chicago in total hits (115) this season while batting .258 with 62 extra-base hits. He's slugging .528 with an on-base percentage of .295.
• Among qualified batters, his batting average ranks him 78th, his on-base percentage 142nd, and his slugging percentage 10th.
• Seiya Suzuki is batting .251 with a .510 slugging percentage and 84 RBI this year.
• Suzuki has logged a hit or more in three straight games. During his last five outings he is hitting .353 with a double, a home run, three walks and three RBIs.
• Nico Hoerner has an OPS of .715, fueled by an OBP of .338 and a team-best slugging percentage of .376 this season.

Cardinals Player Leaders

• Brendan Donovan has a .349 on-base percentage and a .402 slugging percentage, both team-best numbers for the Cardinals. He's batting .278.
• He ranks 31st in batting average, 46th in on-base percentage and 104th in slugging percentage among all qualified batters in MLB.
• Alec Burleson is hitting .282 with 19 doubles, 14 home runs and 31 walks. He's slugging .449 with an on-base percentage of .337.
• Including all qualified hitters, he is 26th in batting average, 63rd in on-base percentage and 64th in slugging percentage.
• Willson Contreras has put up 105 hits, a team-best for the Cardinals.
• Masyn Winn has 25 doubles, eight home runs and 29 walks while hitting .269.

Cubs vs Cardinals Head to Head

• 8/9/2025: 9-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/8/2025: 5-0 STL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 7/5/2025: 8-6 STL (Favorite: Cubs, Spread: -1.5, Total: 11, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 7/4/2025: 11-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/26/2025: 3-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/25/2025: 8-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/24/2025: 8-7 STL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/23/2025: 8-2 STL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/4/2024: 6-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 8/3/2024: 5-4 STL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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