Top 25 College Basketball Picks & Predictions Today - March 22

No. 2 Houston and No. 24 Gonzaga square off at 8:40 p.m. ET, which is one of nine games on Saturday that feature teams ranked in the Top 25 AP Poll. See all of the matchups below, along with our picks and projections.

If you're looking for additional betting information for today in March Madness, we've got you covered with betting odds for each of the important matchups.

Purdue vs. McNeese

• Matchup: McNeese Cowboys vs. No. 22 Purdue Boilermakers
• Projected Winner: Purdue (53.37% win probability)
• Spread: Purdue (-6.5)
• Time: 12:10 p.m. ET
• Date: March 22
• TV Channel: CBS

Bet on Purdue vs. McNeese with FanDuel Sportsbook.

St. John's vs. Arkansas

• Matchup: Arkansas Razorbacks vs. No. 5 St. John's Red Storm
• Projected Winner: St. John's (67.54% win probability)
• Spread: St. John's (-6.5)
• Time: 2:54 p.m. ET
• Date: March 22
• TV Channel: CBS

Bet on St. John's vs. Arkansas with FanDuel Sportsbook.

Texas A&M vs. Michigan

• Matchup: No. 14 Michigan Wolverines vs. No. 19 Texas A&M Aggies
• Projected Winner: Texas A&M (55.92% win probability)
• Spread: Texas A&M (-2.5)
• Time: 5:30 p.m. ET
• Date: March 22
• TV Channel: CBS

Bet on Texas A&M vs. Michigan with FanDuel Sportsbook.

Texas A&M vs. Michigan

• Matchup: No. 14 Michigan Wolverines vs. No. 19 Texas A&M Aggies
• Projected Winner: Texas A&M (54.31% win probability)
• Spread: Texas A&M (-2.5)
• Time: 5:30 p.m. ET
• Date: March 22
• TV Channel: CBS

Bet on Texas A&M vs. Michigan with FanDuel Sportsbook.

Texas Tech vs. Drake

• Matchup: Drake Bulldogs vs. No. 9 Texas Tech Red Raiders
• Projected Winner: Texas Tech (62.81% win probability)
• Spread: Texas Tech (-7.5)
• Time: 6:10 p.m. ET
• Date: March 22
• TV Channel: TNT

Bet on Texas Tech vs. Drake with FanDuel Sportsbook.

Auburn vs. Creighton

• Matchup: Creighton Bluejays vs. No. 4 Auburn Tigers
• Projected Winner: Auburn (70.40% win probability)
• Spread: Auburn (-8.5)
• Time: 7:10 p.m. ET
• Date: March 22
• TV Channel: TBS

Bet on Auburn vs. Creighton with FanDuel Sportsbook.

Wisconsin vs. BYU

• Matchup: No. 17 BYU Cougars vs. No. 13 Wisconsin Badgers
• Projected Winner: Wisconsin (62.07% win probability)
• Time: 8 p.m. ET
• Date: March 23
• TV Channel: CBS

Bet on Wisconsin vs. BYU with FanDuel Sportsbook.

Houston vs. Gonzaga

• Matchup: No. 24 Gonzaga Bulldogs vs. No. 2 Houston Cougars
• Projected Winner: Houston (63.66% win probability)
• Spread: Houston (-5.5)
• Time: 8:40 p.m. ET
• Date: March 23
• TV Channel: TNT

Bet on Houston vs. Gonzaga with FanDuel Sportsbook.

Tennessee vs. UCLA

• Matchup: UCLA Bruins vs. No. 6 Tennessee Volunteers
• Projected Winner: Tennessee (68.03% win probability)
• Spread: Tennessee (-5.5)
• Time: 9:40 p.m. ET
• Date: March 23
• TV Channel: TBS

Bet on Tennessee vs. UCLA with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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