Cavaliers vs. Pistons Eastern Semifinals Prediction, Odds, Picks, Best Bets for May 11

Cavaliers vs. Pistons Game Info

• Date: Monday, May 11, 2026
• Time: 8 p.m. ET
• Venue: Rocket Arena -- Cleveland, Ohio
• Coverage: NBC/Peacock

The Detroit Pistons are slight 3.5-point underdogs for Game 4 of the second round of the NBA Playoffs against the Cleveland Cavaliers at Rocket Arena on Monday, tipping off at 8 p.m. ET on NBC/Peacock. The Pistons have a 2-1 series lead. The point total is 213.5 in the matchup.

Cavaliers vs. Pistons Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Cavaliers vs. Pistons Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Cavaliers win (52.3%)

Cavaliers vs. Pistons Betting Trends

• The Cavaliers have covered the spread 33 times over 82 games with a set spread.
• The Pistons are 44-35-2 against the spread this year.
• Cavaliers games have finished with a final combined score above the over/under 41 times this season.
• Pistons games this year have gone over the point total 48.8% of the time (40 out of 82 games with a set point total).
• Cleveland has covered the spread in a higher percentage of its home games than away games. It has covered 17 times in 41 opportunities at home, and it has covered 16 times in 41 opportunities in road games.
• The Cavaliers have hit the over on the over/under in a lower percentage of games at home (41.5%) than games on the road (58.5%).
• This year, Detroit is 21-19-1 at home against the spread (.512 winning percentage). Away, it is 23-16-1 ATS (.561).
• Looking at the over/under, Pistons games have finished over 48.8% of the time this year, both at home (20 of 41) and on the road (20 of 41).

Cavaliers Leaders

• Donovan Mitchell averages 27.9 points, 4.5 rebounds and 5.7 assists.
• James Harden is averaging 23.6 points, 4.8 boards and 8 assists. Defensively, he averages 1.1 steals and 0.4 blocked shots.
• Evan Mobley averages 18.2 points, 9 rebounds and 3.6 assists, shooting 54.6% from the field and 29.7% from beyond the arc, with 1 made treys per contest.
• Jarrett Allen is averaging 15.4 points, 8.5 rebounds and 1.8 assists. Defensively, he averages 1 steal and 0.8 blocked shots.
• Jaylon Tyson averages 13.2 points, 5.1 rebounds and 2.2 assists, shooting 49.3% from the field and 44.6% from downtown (fourth in league), with 2 made treys per contest.

Pistons Leaders

• Cade Cunningham averages 23.9 points, 5.5 boards and 9.9 assists. He is also draining 46.1% of his shots from the floor and 34.2% from beyond the arc, with 2 triples per game.
• The Pistons get 19.5 points per game from Jalen Duren, plus 10.5 rebounds and 2 assists.
• The Pistons are receiving 9.9 points, 5.7 boards and 3.1 assists per game from Ausar Thompson.
• Per game, Tobias Harris gives the Pistons 13.3 points, 5.1 rebounds and 2.5 assists, plus 0.9 steals and 0.4 blocks.
• Duncan Robinson averages 12.2 points, 2.7 rebounds and 2.1 assists. He is draining 45.6% of his shots from the floor and 41% from 3-point range, with 2.9 treys per game.

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