Cardinals vs Athletics Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 1

Odds updated as of 11:12 p.m.

The Monday slate in MLB includes a matchup between the St. Louis Cardinals and the Athletics.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Cardinals vs Athletics Game Info

• St. Louis Cardinals (68-70) vs. Athletics (63-75)
• Date: Monday, September 1, 2025
• Time: 2:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: FDSMW and NBCS-CA

Cardinals vs Athletics Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-148) | OAK: (+126)
• Spread: STL: -1.5 (+140) | OAK: +1.5 (-170)
• Total: 8 -- Over: (-106) | Under: (-114)

Cardinals vs Athletics Probable Starting Pitchers

Probable Pitchers: Sonny Gray (Cardinals) - 12-7, 4.19 ERA vs Luis Morales (Athletics) - 2-0, 1.19 ERA

The Cardinals will give the nod to Sonny Gray (12-7) against the Athletics and Luis Morales (2-0). Gray's team is 13-12-0 against the spread this season in his starts. Gray's team is 12-5 this season when he starts and they are the moneyline favorite. When Morales starts, the Athletics are 3-1-0 against the spread. The Athletics have a 2-1 record in Morales' three starts this season when they were the moneyline underdog.

Cardinals vs Athletics Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (58.2%)

Cardinals vs Athletics Moneyline

• The Cardinals vs Athletics moneyline has the Cardinals as a -148 favorite, while the Athletics are a +126 underdog on the road.

Cardinals vs Athletics Spread

• The Cardinals are 1.5-run favorites on the runline against the Athletics. The Cardinals are +140 to cover, while the Athletics are -170 to cover.

Cardinals vs Athletics Over/Under

• The Cardinals-Athletics game on Sept. 1 has been given an over/under of 8 runs. The over is set at -106 and the under at -114.

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Cardinals vs Athletics Betting Trends

• The Cardinals have won in 30, or 50.8%, of the 59 contests they have been named as odds-on favorites in this year.
• This season, the Cardinals have come away with a win 10 times in 17 chances when named as a favorite of at least -148 or better on the moneyline.
• The Cardinals and their opponents have hit the over in 69 of their 132 games with a total this season.
• The Cardinals are 67-65-0 against the spread in their 132 games with a line set by sportsbooks this season.
• The Athletics have a 45-58 record in games they were the underdog on the moneyline (winning 43.7% of those games).
• The Athletics have gone 18-32 when they have played as a moneyline underdog with odds of +126 or longer (36%).
• The Athletics have combined with their opponents to hit the over on the total 69 times this season for a 69-62-6 record against the over/under.
• The Athletics are 72-65-0 ATS this season.

Cardinals Player Leaders

• Willson Contreras is hitting .253 with 30 doubles, 20 home runs and 41 walks. He has an on-base percentage of .337 while slugging .447.
• Among all qualifying batters in the majors, he ranks 89th in batting average, 62nd in on-base percentage, and 68th in slugging.
• Contreras will look for his third straight game with a hit in this contest. In his last five games he is hitting .105 with a home run, a walk and an RBI.
• Masyn Winn is batting .255 with 27 doubles, nine home runs and 32 walks, while slugging .370 with an on-base percentage of .311.
• Among qualifying hitters, he ranks 86th in batting average, 114th in on-base percentage and 137th in slugging percentage.
• Lars Nootbaar has 102 hits this season and has a slash line of .239/.330/.387.
• Nootbaar brings a two-game hitting streak into this game. In his last five games he is batting .350 with two doubles, a triple and two walks.
• Ivan Herrera has 11 home runs, 50 RBI and a batting average of .286 this season.
• Herrera heads into this matchup on a six-game hitting streak. During his last 10 outings he is batting .257 with a double, a home run, four walks and four RBIs.

Athletics Player Leaders

• Brent Rooker has accumulated a slugging percentage of .496, a team-high for the Athletics. He's batting .271 with an on-base percentage of .343.
• Including all qualified hitters in MLB, he is 41st in batting average, 51st in on-base percentage and 24th in slugging percentage.
• Tyler Soderstrom has 27 doubles, a triple, 23 home runs and 51 walks while hitting .270. He's slugging .469 with an on-base percentage of .343.
• He is currently 45th in batting average, 51st in on-base percentage and 42nd in slugging percentage among all qualifying hitters.
• Shea Langeliers has 105 hits, a team-best for the Athletics.
• Nick Kurtz has 23 doubles, two triples, 27 home runs and 53 walks while hitting .308.

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