Astros vs Royals Prediction, Odds, Moneyline, Spread & Over/Under for May 12

Odds updated as of 6:11 a.m.

The Houston Astros versus the Kansas City Royals is on the MLB schedule for Monday.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Astros vs Royals Game Info

• Houston Astros (20-19) vs. Kansas City Royals (24-18)
• Date: Monday, May 12, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and FDSKC

Astros vs Royals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-116) | KC: (-102)
• Spread: HOU: +1.5 (-194) | KC: -1.5 (+160)
• Total: 8 -- Over: (-122) | Under: (-100)

Astros vs Royals Probable Starting Pitchers

Probable Pitchers: Ryan Gusto (Astros) - 3-1, 2.93 ERA vs Michael Wacha (Royals) - 2-4, 2.98 ERA

This contest's pitching matchup is set, as the Astros will send Ryan Gusto (3-1) to the mound, while Michael Wacha (2-4) will answer the bell for the Royals. When Gusto starts, his team is 3-1-0 against the spread this season. Gusto's team has been victorious in 75% of the games he's started as the moneyline favorite with a record of 3-1. The Royals are 3-5-0 ATS in Wacha's eight starts with a set spread. The Royals are 2-2 in Wacha's four starts this season that they were the underdog on the moneyline.

Astros vs Royals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (54.3%)

Astros vs Royals Moneyline

• The Astros vs Royals moneyline has Houston as a -116 favorite, while Kansas City is a -102 underdog on the road.

Astros vs Royals Spread

• The Royals are 1.5-run favorites against the spread for this matchup with the Astros. The Royals are +160 to cover, while the Astros are -194 to cover as a 1.5-run underdog on the runline.

Astros vs Royals Over/Under

• An over/under of 8 has been set for Astros-Royals on May 12, with the over being -122 and the under -100.

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Astros vs Royals Betting Trends

• The Astros have come away with 15 wins in the 28 contests they have been listed as the favorites in this season.
• Houston has a record of 15-12 when favored by -116 or more this year.
• The Astros and their opponents have gone over in 17 of their 39 games with a total set by sportsbooks this season.
• In 39 games with a line this season, the Astros have a mark of 22-17-0 against the spread.
• The Royals have won 11 of the 23 games they were the underdog on the moneyline this season (47.8%).
• When playing as a moneyline underdog with odds of -102 or longer, Kansas City has a 7-11 record (winning only 38.9% of its games).
• The Royals have played in 42 games with a set over/under, and have combined with their opponents to go over the total 14 times (14-27-1).
• The Royals have a 21-21-0 record ATS this season (covering 50% of the time).

Astros Player Leaders

• Jeremy Pena leads Houston with 43 hits and a team-best slugging percentage of .433. He's batting .287 with an on-base percentage of .345.
• Among the qualifying hitters in the majors, his batting average ranks 30th, his on-base percentage ranks 65th, and he is 64th in slugging.
• Pena has recorded at least one hit in four straight games. In his last five games he is hitting .318 with two doubles, a home run, a walk and seven RBIs.
• Isaac Paredes leads Houston in OBP (.380) this season, fueled by 37 hits. He's batting .264 while slugging .407.
• He is 59th in batting average, 20th in on-base percentage and 86th in slugging in MLB.
• Paredes has picked up a hit in four games in a row. During his last five outings he is batting .313 with three doubles, seven walks and three RBIs.
• Jose Altuve is batting .259 with a .374 slugging percentage and 14 RBI this year.
• Jake Meyers has been key for Houston with 32 hits, an OBP of .358 plus a slugging percentage of .409.

Royals Player Leaders

• Bobby Witt Jr. has totaled 51 hits with a .386 on-base percentage and a .512 slugging percentage, all club-highs for the Royals. He's batting .315.
• Including all the qualifying players in the big leagues, he is 11th in batting average, 16th in on-base percentage and 20th in slugging percentage.
• Maikel Garcia is batting .306 with 10 doubles, a triple, four home runs and 16 walks. He's slugging .472 with an on-base percentage of .373.
• Including all qualifying hitters, he ranks 17th in batting average, 30th in on-base percentage and 41st in slugging percentage.
• Vinnie Pasquantino is batting .217 with five doubles, a triple, six home runs and 10 walks.
• Jonathan India is batting .224 with eight doubles, a home run and 21 walks.

Astros vs Royals Head to Head

• 4/27/2025: 7-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/26/2025: 2-0 KC (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/25/2025: 2-0 KC (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/1/2024: 7-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/31/2024: 5-2 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 8/30/2024: 3-2 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 8/29/2024: 6-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 4/11/2024: 13-3 KC (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/10/2024: 11-2 KC (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/9/2024: 4-3 KC (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)

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