Astros vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for May 9

Odds updated as of 8:11 a.m.

In MLB action on Friday, the Houston Astros face the Cincinnati Reds.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Astros vs Reds Game Info

• Houston Astros (18-18) vs. Cincinnati Reds (19-20)
• Date: Friday, May 9, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and FDSOH

Astros vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-178) | CIN: (+150)
• Spread: HOU: -1.5 (+122) | CIN: +1.5 (-146)
• Total: 7.5 -- Over: (-124) | Under: (+102)

Astros vs Reds Probable Starting Pitchers

Probable Pitchers: Hunter Brown (Astros) - 5-1, 1.67 ERA vs Nicholas Martínez (Reds) - 1-3, 4.19 ERA

This contest's pitching matchup is set, as the Astros will send Hunter Brown (5-1) to the mound, while Nicholas Martinez (1-3) will answer the bell for the Reds. Brown and his team have a record of 5-2-0 against the spread when he starts. Brown's team has a record of 4-2 this season when he starts and they are the favorite on the moneyline. The Reds have a 2-5-0 ATS record in Martínez's seven starts with a set spread. The Reds were the underdog on the moneyline for four Martinez starts this season -- they lost all of the games.

Astros vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (59%)

Astros vs Reds Moneyline

• Cincinnati is the underdog, +150 on the moneyline, while Houston is a -178 favorite at home.

Astros vs Reds Spread

• The Reds are at the Astros, and are +1.5 on the runline. The Reds are +122 to cover the spread, and the Astros are -146.

Astros vs Reds Over/Under

• A combined run total of 7.5 has been set for Astros-Reds on May 9, with the over at -124 and the under at +102.

Bet on Houston Astros vs. Cincinnati Reds on FanDuel today!

Astros vs Reds Betting Trends

• The Astros have won in 13, or 52%, of the 25 contests they have been named as odds-on favorites in this year.
• Houston has been listed as a favorite of -178 or more on two occasions this season and split those games.
• The Astros and their opponents have gone over in 16 of their 36 games with a total set by sportsbooks this season.
• The Astros are 20-16-0 against the spread in their 36 games that had a posted line this season.
• The Reds have a 9-12 record in games they were the underdog on the moneyline (winning 42.9% of those games).
• Cincinnati is 1-2 (winning only 33.3% of its games) when playing as a moneyline underdog of +150 or longer.
• The Reds have had an over/under set by oddsmakers 38 times, and have combined with opponents to go over the total in 17 of those games (17-20-1).
• The Reds have a 20-18-0 record against the spread this season (covering 52.6% of the time).

Astros Player Leaders

• Jeremy Pena leads Houston in slugging percentage (.434) and total hits (38) this season. He's batting .279 with an on-base percentage of .340.
• Among qualified hitters in the majors, his batting average ranks 42nd, his on-base percentage ranks 64th, and he is 59th in slugging.
• Isaac Paredes leads Houston in OBP (.368) this season, fueled by 33 hits. He's batting .256 while slugging .388.
• Among qualifying hitters, he is 68th in batting average, 38th in on-base percentage and 101st in slugging percentage.
• Jose Altuve has collected 36 base hits, an OBP of .299 and a slugging percentage of .364 this season.
• Jake Meyers is batting .297 with a .351 OBP and 13 RBI for Houston this season.
• Meyers has safely hit in eight straight games. In his last 10 games he is hitting .364 with a double, a triple, two home runs, four walks and eight RBIs.

Reds Player Leaders

• Elly De La Cruz has five doubles, five home runs and 17 walks while batting .258. He's slugging .391 with an on-base percentage of .339.
• He ranks 66th in batting average, 68th in on-base percentage and 97th in slugging percentage among all qualified hitters in the majors.
• TJ Friedl is slugging .388 to lead his team. He has a batting average of .272 with an on-base percentage of .339.
• His batting average is 53rd among all qualified players, his on-base percentage ranks 68th, and he is 101st in slugging.
• Gavin Lux has accumulated a team-best OBP (.388), and paces the Reds in hits (36).
• Jose Trevino is batting .310 with nine doubles, three home runs and five walks.

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