Astros vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 16

Odds updated as of 2:11 a.m.

The Saturday schedule in MLB includes a matchup between the Houston Astros and the Baltimore Orioles.

All the info you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Astros vs Orioles Game Info

• Houston Astros (68-54) vs. Baltimore Orioles (56-66)
• Date: Saturday, August 16, 2025
• Time: 7:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and MASN2

Astros vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-220) | BAL: (+184)
• Spread: HOU: -1.5 (-102) | BAL: +1.5 (-118)
• Total: 7.5 -- Over: (-112) | Under: (-108)

Astros vs Orioles Probable Starting Pitchers

Probable Pitchers: Jason Alexander (Astros) - 3-1, 5.02 ERA vs Rico Garcia (Orioles) - 0-0, 3.71 ERA

The Astros will look to Jason Alexander (3-1) against the Orioles and Rico Garcia. Alexander's team is 4-1-0 against the spread this season in his starts. Alexander's team has a record of 2-1 this season when he starts and they are the favorite on the moneyline. Garcia's team was never a moneyline underdog a season ago in games he pitched.

Astros vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (57.5%)

Astros vs Orioles Moneyline

• The moneyline numbers for Astros vs. Orioles reveal Houston as the favorite (-220) and Baltimore as the underdog (+184) on the road.

Astros vs Orioles Spread

• The Orioles are at +1.5 on the runline against the Astros. The Orioles are -118 to cover the spread, and the Astros are -102.

Astros vs Orioles Over/Under

• The over/under for Astros-Orioles on Aug. 16 is 7.5. The over is -112, and the under is -108.

Bet on Houston Astros vs. Baltimore Orioles on FanDuel today!

Astros vs Orioles Betting Trends

• The Astros have been victorious in 42, or 53.2%, of the 79 contests they have been chosen as favorites in this season.
• This season Houston has been victorious four times in seven chances when named as a favorite of at least -220 on the moneyline.
• Contests with the Astros have gone over the total set by oddsmakers in 53 of 121 chances this season.
• In 121 games with a line this season, the Astros have a mark of 61-60-0 against the spread.
• The Orioles have put together a 29-34 record in games they were the underdog on the moneyline (winning 46% of those games).
• Baltimore is 2-1 (winning 66.7% of its games) when playing as a moneyline underdog of +184 or longer.
• The Orioles have combined with opponents to hit the over on the total 50 times this season for a 50-65-4 record against the over/under.
• The Orioles have a 54-65-0 record against the spread this season (covering 45.4% of the time).

Astros Player Leaders

• Jose Altuve has an OPS of .810, fueled by an OBP of .345 and a team-best slugging percentage of .465 this season. He has a .281 batting average.
• Among qualifying batters in baseball, he ranks 26th in batting average, 51st in on-base percentage, and 45th in slugging.
• Jeremy Pena leads the Astros in OBP (.373) and total hits (115) this season. He's batting .318 while slugging .492.
• Among qualifying hitters, his batting average places him second, his on-base percentage 13th, and his slugging percentage 27th.
• Pena heads into this matchup looking to extend his three-game hit streak. In his last five games he is batting .273 with two home runs, a walk and two RBIs.
• Yainer Diaz has collected 104 base hits, an OBP of .280 and a slugging percentage of .420 this season.
• Christian Walker has 16 home runs, 65 RBI and a batting average of .232 this season.

Orioles Player Leaders

• Gunnar Henderson has 122 hits with a .351 on-base percentage and a .466 slugging percentage, all club-bests for the Orioles. He's batting .283.
• Including all qualified hitters in the big leagues, he ranks 24th in batting average, 43rd in on-base percentage and 43rd in slugging percentage.
• Henderson brings an eight-game hitting streak into this game. During his last 10 games he is hitting .257 with four doubles, a home run, two walks and six RBIs.
• Jackson Holliday is batting .248 with 16 doubles, two triples, 14 home runs and 29 walks. He's slugging .385 with an on-base percentage of .300.
• Including all qualified hitters, he ranks 104th in batting average, 132nd in on-base percentage and 130th in slugging percentage.
• Adley Rutschman is hitting .232 with 16 doubles, a triple, nine home runs and 37 walks.
• Jordan Westburg is hitting .268 with nine doubles, a triple, 14 home runs and 15 walks.

Astros vs Orioles Head to Head

• 8/15/2025: 7-0 BAL (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 8/25/2024: 6-3 HOU (Favorite: Orioles, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/24/2024: 3-2 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/23/2024: 7-5 BAL (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/22/2024: 6-0 HOU (Favorite: Orioles, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/23/2024: 8-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/22/2024: 5-1 HOU (Favorite: Orioles, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 6/21/2024: 14-11 HOU (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 9/20/2023: 2-1 HOU (Favorite: Orioles, Spread: -1.5, Total: 9, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 9/19/2023: 9-5 BAL (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -184, Underdog Moneyline: +154)

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