Yankees vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 16

Odds updated as of 7:12 p.m.

The New York Yankees will face the St. Louis Cardinals in MLB action on Saturday.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Yankees vs Cardinals Game Info

• New York Yankees (65-57) vs. St. Louis Cardinals (61-62)
• Date: Saturday, August 16, 2025
• Time: 7:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: FOX

Yankees vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-146) | STL: (+124)
• Spread: NYY: -1.5 (+115) | STL: +1.5 (-138)
• Total: 9 -- Over: (-102) | Under: (-120)

Yankees vs Cardinals Probable Starting Pitchers

Probable Pitchers: Max Fried (Yankees) - 12-5, 2.94 ERA vs Sonny Gray (Cardinals) - 11-5, 4.06 ERA

The Yankees will look to Max Fried (12-5) against the Cardinals and Sonny Gray (11-5). Fried's team is 13-11-0 against the spread this season in his starts. Fried's team has a record of 15-9 this season when he starts and they are the favorite on the moneyline. The Cardinals have a 12-10-0 ATS record in Gray's 22 starts that had a set spread. The Cardinals have been the moneyline underdog in seven of Gray's starts this season, and they went 5-2 in those matchups.

Yankees vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (50.7%)

Yankees vs Cardinals Moneyline

• New York is a -146 favorite on the moneyline, while St. Louis is a +124 underdog at home.

Yankees vs Cardinals Spread

• The Yankees are at the Cardinals and are favored by 1.5 runs (+115 to cover) on the runline. St. Louis is -138 to cover.

Yankees vs Cardinals Over/Under

• The over/under for Yankees-Cardinals on Aug. 16 is 9. The over is -102, and the under is -120.

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Yankees vs Cardinals Betting Trends

• The Yankees have been victorious in 57, or 56.4%, of the 101 contests they have been chosen as favorites in this season.
• This year New York has won 42 of 65 games when listed as at least -146 on the moneyline.
• The Yankees' games have gone over the total in 54 of their 120 opportunities.
• The Yankees are 51-69-0 against the spread in their 120 games with a line set by sportsbooks this season.
• The Cardinals have won 49.2% of the games this season they were the moneyline underdog (31-32).
• St. Louis is 10-14 (winning 41.7% of its games) when playing as a moneyline underdog of +124 or longer.
• In the 118 games bookmakers have set an over/under for the Cardinals, they have combined with opponents to go over the total 59 times (59-54-5).
• The Cardinals have a 61-57-0 record against the spread this season (covering 51.7% of the time).

Yankees Player Leaders

• Aaron Judge has 134 hits and an OBP of .442 to go with a slugging percentage of .680. All three of those stats are best among New York hitters this season. He has a .330 batting average, as well.
• Among qualified hitters in the majors, his batting average ranks first, his on-base percentage ranks first, and he is first in slugging.
• Cody Bellinger has 20 doubles, five triples, 22 home runs and 37 walks. He's batting .267 and slugging .485 with an on-base percentage of .322.
• He is 52nd in batting average, 94th in on-base percentage and 28th in slugging among qualifying hitters.
• Anthony Volpe is batting .217 with a .418 slugging percentage and 65 RBI this year.
• Trent Grisham is batting .242 with a .347 OBP and 46 RBI for New York this season.

Cardinals Player Leaders

• Brendan Donovan has put up a team-high OBP (.348) and slugging percentage (.402). He's batting .279.
• Including all the qualified hitters in the majors, he ranks 29th in batting average, 46th in on-base percentage and 104th in slugging percentage.
• Alec Burleson's 107 hits lead his team. He has a batting average of .279 while slugging .446 with an on-base percentage of .333.
• He is currently 29th in batting average, 68th in on-base percentage and 67th in slugging percentage among all qualified hitters.
• Willson Contreras is hitting .255 with 29 doubles, 16 home runs and 39 walks.
• Masyn Winn has 26 doubles, eight home runs and 31 walks while hitting .265.

Yankees vs Cardinals Head to Head

• 8/15/2025: 4-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/1/2024: 14-7 STL (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 8/31/2024: 6-5 STL (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 8/30/2024: 6-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 7/2/2023: 5-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/1/2023: 6-2 NYY (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/1/2023: 11-4 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/7/2022: 12-9 STL (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/6/2022: 1-0 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/5/2022: 4-3 STL (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -164, Underdog Moneyline: +138)

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