Astros vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 15

Odds updated as of 8:11 p.m.

The MLB slate on Friday includes the Houston Astros taking on the Baltimore Orioles.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding this game.

Astros vs Orioles Game Info

• Houston Astros (68-53) vs. Baltimore Orioles (55-66)
• Date: Friday, August 15, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and MASN2

Astros vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-220) | BAL: (+184)
• Spread: HOU: -1.5 (-102) | BAL: +1.5 (-118)
• Total: 7.5 -- Over: (-112) | Under: (-108)

Astros vs Orioles Probable Starting Pitchers

Probable Pitchers: Framber Valdez (Astros) - 11-5, 2.97 ERA vs Brandon Young (Orioles) - 0-6, 6.70 ERA

The Astros will give the nod to Framber Valdez (11-5, 2.97 ERA), who is eyeing win No. 12 on the season, and the Orioles will counter with Brandon Young (0-6, 6.70 ERA). Valdez and his team are 10-12-0 ATS this season when he starts. When Valdez starts a game and his team is the favorite on the moneyline, they have a record of 11-7. The Orioles have gone 4-5-0 ATS in Young's nine starts with a set spread. The Orioles have been the moneyline underdog in seven of Young's starts this season, and they went 1-6 in those games.

Astros vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (57.5%)

Astros vs Orioles Moneyline

• Houston is the favorite, -220 on the moneyline, while Baltimore is a +184 underdog on the road.

Astros vs Orioles Spread

• The Orioles are at the Astros, and are +1.5 on the runline. The Orioles are -102 to cover the spread, and the Astros are -118.

Astros vs Orioles Over/Under

• A combined run total of 7.5 has been set for Astros-Orioles on Aug. 15, with the over at -112 and the under at -108.

Bet on Houston Astros vs. Baltimore Orioles on FanDuel today!

Astros vs Orioles Betting Trends

• The Astros have been favorites in 78 games this season and have come away with the win 42 times (53.8%) in those contests.
• This year Houston has won four of six games when listed as at least -220 on the moneyline.
• The Astros and their opponents have gone over in 53 of their 120 games with a total set by sportsbooks this season.
• In 120 games with a line this season, the Astros have a mark of 61-59-0 against the spread.
• The Orioles have won 28 of the 62 games they were listed as the moneyline underdog this season (45.2%).
• Baltimore has a 2-1 record (winning 66.7% of its games) when playing as a moneyline underdog of +184 or longer.
• The Orioles have played in 118 games with a set over/under, and have combined with their opponents to go over the total 50 times (50-64-4).
• The Orioles have a 53-65-0 record ATS this season.

Astros Player Leaders

• Jose Altuve leads Houston in slugging percentage (.469) thanks to 40 extra-base hits. He has a .283 batting average and an on-base percentage of .348.
• Among all qualified hitters in MLB, he ranks 25th in batting average, 45th in on-base percentage, and 39th in slugging.
• Jeremy Pena has 115 hits and an OBP of .373, both of which lead the Astros this season. He's batting .318 and slugging .492.
• Among qualifying hitters, his batting average ranks him second, his on-base percentage 14th, and his slugging percentage 26th.
• Pena takes a three-game streak with at least one hit into this matchup. In his last five games he is batting .273 with two home runs, a walk and two RBIs.
• Yainer Diaz has collected 104 base hits, an OBP of .282 and a slugging percentage of .423 this season.
• Diaz has logged a hit or more in two straight games. In his last five games he is hitting .250 with a home run and three RBIs.
• Christian Walker has been key for Houston with 102 hits, an OBP of .300 plus a slugging percentage of .394.

Orioles Player Leaders

• Gunnar Henderson has racked up a team-high OBP (.352) and slugging percentage (.468), while leading the Orioles in hits (121, while batting .283).
• Including all qualified hitters, he is 25th in batting average, while his on-base percentage is 41st and he is 42nd in slugging.
• Henderson hopes to build on a seven-game hitting streak in this matchup. In his last 10 games he is batting .265 with four doubles, a home run, three walks and five RBIs.
• Jackson Holliday is batting .248 with 16 doubles, two triples, 14 home runs and 29 walks. He's slugging .387 with an on-base percentage of .301.
• Including all qualified players, he is 105th in batting average, 131st in on-base percentage and 127th in slugging percentage.
• Adley Rutschman has 16 doubles, a triple, nine home runs and 37 walks while batting .232.
• Jordan Westburg has nine doubles, a triple, 14 home runs and 14 walks while hitting .265.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!