Astros vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for July 28

Odds updated as of 7:11 p.m.

MLB action on Monday includes the Houston Astros playing the Washington Nationals.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Astros vs Nationals Game Info

• Houston Astros (60-46) vs. Washington Nationals (43-62)
• Date: Monday, July 28, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and MASN2

Astros vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-260) | WSH: (+215)
• Spread: HOU: -1.5 (-118) | WSH: +1.5 (-102)
• Total: 7.5 -- Over: (-100) | Under: (-122)

Astros vs Nationals Probable Starting Pitchers

Probable Pitchers: Framber Valdez (Astros) - 11-4, 2.67 ERA vs Brad Lord (Nationals) - 2-5, 3.39 ERA

The Astros will give the ball to Framber Valdez (11-4, 2.67 ERA), who is eyeing win No. 12 on the season, and the Nationals will turn to Brad Lord (2-5, 3.39 ERA). When Valdez starts, his team is 10-9-0 against the spread this season. Valdez's team is 11-5 this season when he starts and they are the moneyline favorite. The Nationals have a 3-3-0 ATS record in Lord's six starts that had a set spread. The Nationals have a 3-1 record in Lord's four starts this season when they were the underdog on the moneyline.

Astros vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (68.6%)

Astros vs Nationals Moneyline

• Washington is the underdog, +215 on the moneyline, while Houston is a -260 favorite at home.

Astros vs Nationals Spread

• The Astros are hosting the Nationals and are favored by 1.5 runs on the spread. The Astros are -118 to cover the runline, with the Nationals being -102.

Astros vs Nationals Over/Under

• The Astros-Nationals game on July 28 has been given an over/under of 7.5 runs. The over is set at -100 and the under at -122.

Bet on Houston Astros vs. Washington Nationals on FanDuel today!

Astros vs Nationals Betting Trends

• The Astros have been chosen as favorites in 72 games this year and have walked away with the win 39 times (54.2%) in those games.
• Houston has been listed as a favorite of -260 or more on two occasions this season and won both games.
• The Astros and their opponents have gone over the total this season in 43 of their 105 opportunities.
• In 105 games with a line this season, the Astros have a mark of 53-52-0 against the spread.
• The Nationals have been the underdog on the moneyline 81 total times this season. They've finished 37-44 in those games.
• Washington has a 1-3 record (winning only 25% of its games) when it has played as a moneyline underdog of +215 or longer.
• The Nationals have combined with opponents to go over the total 55 times this season for a 55-42-2 record against the over/under.
• The Nationals have put together a 52-47-0 record ATS this season (covering 52.5% of the time).

Astros Player Leaders

• Jose Altuve has an OPS of .803, fueled by an OBP of .343 and a team-best slugging percentage of .460 this season. He has a .280 batting average.
• He ranks 35th in batting average, 54th in on-base percentage, and 50th in slugging among qualified hitters in MLB.
• Altuve will look for his third straight game with a hit in this contest. During his last five outings he is batting .333 with three walks.
• Yainer Diaz has 14 doubles, a triple, 13 home runs and 14 walks. He's batting .245 and slugging .400 with an on-base percentage of .275.
• Among qualifying batters, he ranks 110th in batting average, 154th in on-base percentage and 106th in slugging percentage.
• Christian Walker is batting .233 with a .380 slugging percentage and 53 RBI this year.
• Walker heads into this game with two games in a row with at least one hit. During his last five outings he is batting .250 with two doubles, two walks and two RBIs.
• Cam Smith has been key for Houston with 85 hits, an OBP of .329 plus a slugging percentage of .385.

Nationals Player Leaders

• James Wood has racked up a team-high OBP (.367) and slugging percentage (.501), and leads the Nationals in hits (103, while batting .263).
• Including all qualifying hitters in MLB, his batting average puts him 70th, his on-base percentage ranks 23rd, and he is 21st in slugging.
• C.J. Abrams has 23 doubles, four triples, 14 home runs and 25 walks while batting .275. He's slugging .475 with an on-base percentage of .340.
• Including all qualified hitters, his batting average puts him 41st, his on-base percentage ranks 59th, and he is 33rd in slugging.
• Luis Garcia is batting .263 with 22 doubles, eight home runs and 20 walks.
• Nathaniel Lowe is hitting .225 with 15 doubles, two triples, 15 home runs and 38 walks.

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