Astros vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for July 9

Odds updated as of 7:12 p.m.

The Houston Astros versus the Cleveland Guardians is on the MLB schedule for Wednesday.

We've got you covered, in terms of the most important info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Astros vs Guardians Game Info

• Houston Astros (55-37) vs. Cleveland Guardians (42-48)
• Date: Wednesday, July 9, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and CLEG

Astros vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-154) | CLE: (+130)
• Spread: HOU: -1.5 (+140) | CLE: +1.5 (-170)
• Total: 7.5 -- Over: (-110) | Under: (-110)

Astros vs Guardians Probable Starting Pitchers

Probable Pitchers: Brandon Walter (Astros) - 1-1, 4.15 ERA vs Slade Cecconi (Guardians) - 3-4, 3.56 ERA

The Astros will call on Brandon Walter (1-1) versus the Guardians and Slade Cecconi (3-4). Walter and his team have a record of 3-3-0 against the spread when he starts. When Walter starts a game and his team is the favorite on the moneyline, they have a record of 2-1. The Guardians have gone 6-3-0 ATS in Cecconi's nine starts with a set spread. The Guardians have been the moneyline underdog in five of Cecconi's starts this season, and they went 2-3 in those matchups.

Astros vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (67.8%)

Astros vs Guardians Moneyline

• Cleveland is a +130 underdog on the moneyline, while Houston is a -154 favorite at home.

Astros vs Guardians Spread

• The Guardians are at +1.5 on the runline against the Astros. The Guardians are -170 to cover the spread, and the Astros are +140.

Astros vs Guardians Over/Under

• Astros versus Guardians on July 9 has an over/under of 7.5 runs, with the odds on the over -110 and the under set at -110.

Bet on Houston Astros vs. Cleveland Guardians on FanDuel today!

Astros vs Guardians Betting Trends

• The Astros have been victorious in 37, or 58.7%, of the 63 contests they have been chosen as favorites in this season.
• Houston has a record of 13-8 in contests when sportsbooks favor them by -154 or more on the moneyline.
• The Astros and their opponents have gone over the total this season in 38 of their 91 opportunities.
• The Astros are 47-44-0 against the spread in their 91 games with a line set by sportsbooks this season.
• The Guardians have compiled a 23-35 record in games they were the underdog on the moneyline (winning 39.7% of those games).
• When playing as a moneyline underdog with odds of +130 or longer, Cleveland has gone 6-13 (31.6%).
• The Guardians have played in 88 games with an over/under set, and have combined with opponents to go over the total 38 times (38-47-3).
• The Guardians are 44-44-0 ATS this season.

Astros Player Leaders

• Isaac Paredes is hitting .255 with 12 doubles, a triple, 19 home runs and 47 walks. He has an on-base percentage of .358 while slugging .471.
• Among qualified hitters in the majors, his batting average ranks 89th, his on-base percentage ranks 33rd, and he is 41st in slugging.
• Jose Altuve has 13 doubles, a triple, 16 home runs and 32 walks. He's batting .272 and slugging .456 with an on-base percentage of .332.
• Among qualifying batters, he is 50th in batting average, 74th in on-base percentage and 55th in slugging percentage.
• Jake Meyers has 89 hits this season and has a slash line of .308/.369/.405.
• Yainer Diaz has been key for Houston with 75 hits, an OBP of .275 plus a slugging percentage of .400.

Guardians Player Leaders

• Jose Ramirez has a team-high OBP (.364), and leads the Guardians in hits (98). He's batting .299 and slugging.
• Including all the qualified hitters in the majors, he ranks 10th in batting average, 29th in on-base percentage and 20th in slugging percentage.
• Steven Kwan's .409 slugging percentage paces his team. He has a batting average of .292 with an on-base percentage of .351.
• Including all qualifying players, he ranks 17th in batting average, 44th in on-base percentage and 94th in slugging percentage.
• Carlos Santana is batting .230 with seven doubles, 10 home runs and 41 walks.
• Angel Martinez is batting .238 with 13 doubles, a triple, six home runs and nine walks.

Astros vs Guardians Head to Head

• 7/8/2025: 10-6 CLE (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 7/7/2025: 7-5 CLE (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/8/2025: 4-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/7/2025: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/6/2025: 4-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/28/2024: 4-3 HOU (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 9/27/2024: 5-2 HOU (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/2/2024: 8-2 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/1/2024: 3-2 CLE (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/30/2024: 10-9 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -172, Underdog Moneyline: +144)

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