Astros vs Athletics Prediction, Odds, Moneyline, Spread & Over/Under for July 25

Odds updated as of 7:11 p.m.

In MLB action on Friday, the Houston Astros take on the Athletics.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Astros vs Athletics Game Info

• Houston Astros (60-43) vs. Athletics (43-62)
• Date: Friday, July 25, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and NBCS-CA

Astros vs Athletics Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-215) | OAK: (+180)
• Spread: HOU: -1.5 (+102) | OAK: +1.5 (-122)
• Total: 7.5 -- Over: (-108) | Under: (-112)

Astros vs Athletics Probable Starting Pitchers

Probable Pitchers: Ryan Gusto (Astros) - 6-3, 4.46 ERA vs Jeffrey Springs (Athletics) - 8-7, 4.34 ERA

The probable starters are Ryan Gusto (6-3) for the Astros and Jeffrey Springs (8-7) for the Athletics. Gusto's team is 5-7-0 against the spread in his starts this season. When Gusto starts a game and his team is the favorite on the moneyline, they have a record of 5-6. The Athletics have gone 11-8-0 ATS in Springs' 19 starts that had a set spread. The Athletics are 8-6 in Springs' 14 starts this season that they were the underdog on the moneyline.

Astros vs Athletics Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (63.5%)

Astros vs Athletics Moneyline

• The Astros vs Athletics moneyline has the Astros as a -215 favorite, while the Athletics are a +180 underdog on the road.

Astros vs Athletics Spread

• The Astros are 1.5-run favorites on the runline against the Athletics. The Astros are +102 to cover, while the Athletics are -122 to cover.

Astros vs Athletics Over/Under

• An over/under of 7.5 has been set for Astros-Athletics on July 25, with the over being -108 and the under -112.

Bet on Houston Astros vs. Athletics on FanDuel today!

Astros vs Athletics Betting Trends

• The Astros have come away with 39 wins in the 69 contests they have been listed as the favorites in this season.
• This season, the Astros have come away with a win four times in five chances when named as a favorite of at least -215 or shorter on the moneyline.
• The Astros and their opponents have hit the over in 42 of their 102 games with a total this season.
• The Astros have an against the spread mark of 53-49-0 in 102 games with a line this season.
• The Athletics have won 31 of the 82 games they were listed as the moneyline underdog this season (37.8%).
• In games they have played as a moneyline underdog with odds of +180 or longer, the Athletics have a record of 1-6 (14.3%).
• The Athletics have played in 104 games with a set over/under, and have combined with their opponents to go over the total 54 times (54-45-5).
• The Athletics have covered 50% of their games this season, going 52-52-0 ATS.

Astros Player Leaders

• Jose Altuve has an OPS of .807, fueled by an OBP of .342 and a team-best slugging percentage of .465 this season. He has a .281 batting average.
• Among the qualified hitters in the majors, his batting average ranks 32nd, his on-base percentage ranks 58th, and he is 49th in slugging.
• Altuve has picked up at least one hit in five straight games. In his last five games he is hitting .400 with three doubles, three walks and an RBI.
• Yainer Diaz has 13 doubles, a triple, 13 home runs and 14 walks. He's batting .246 and slugging .402 with an on-base percentage of .277.
• Among qualifiers, he ranks 109th in batting average, 154th in on-base percentage and 102nd in slugging percentage.
• Christian Walker is batting .233 with a .380 slugging percentage and 53 RBI this year.
• Cam Smith has been key for Houston with 84 hits, an OBP of .331 plus a slugging percentage of .394.

Athletics Player Leaders

• Brent Rooker has racked up 112 hits, a team-best for the Athletics. He's batting .275 and slugging .501 with an on-base percentage of .352.
• Including all the qualified hitters in the big leagues, he is 48th in batting average, 43rd in on-base percentage and 21st in slugging percentage.
• Jacob Wilson's .353 on-base percentage and .440 slugging percentage are both team-highs. He has a batting average of .311.
• Including all qualifying players, he ranks fifth in batting average, 41st in on-base percentage and 69th in slugging percentage.
• Tyler Soderstrom has 16 doubles, a triple, 18 home runs and 37 walks while batting .256.
• Lawrence Butler has 24 doubles, two triples, 14 home runs and 42 walks while batting .238.

Astros vs Athletics Head to Head

• 7/24/2025: 5-2 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 6/19/2025: 6-4 OAK (Favorite: Astros, Spread: -1.5, Total: 10.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/18/2025: 11-4 HOU (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 6/17/2025: 13-3 HOU (Favorite: Astros, Spread: -1.5, Total: 11, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 6/16/2025: 3-1 OAK (Favorite: Astros, Spread: -1.5, Total: 10, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/28/2025: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/27/2025: 11-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 9/12/2024: 6-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 9/11/2024: 5-4 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 9/10/2024: 4-3 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!