Arizona vs Colorado Prediction, Odds, Picks, Best Bets for Week 10 2025

In college football action on Saturday, the Arizona Wildcats face the Colorado Buffaloes.

We've got you covered, in terms of the most important information about NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Arizona vs Colorado Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Arizona: (-176) | Colorado: (+148)
• Spread: Arizona: -3.5 (-115) | Colorado: +3.5 (-105)
• Total: 53.5 -- Over: (-104) | Under: (-118)

Arizona vs Colorado Betting Trends

• Arizona has three wins in six games against the spread this year.
• Arizona has covered every time (2-0) as a 3.5-point favorite or greater this season.
• Arizona has played six games this year, and three of them have hit the over.
• Colorado has four wins in eight contests against the spread this year.
• As a 3.5-point underdog or greater, Colorado has one win ATS (1-4) this year.
• Colorado has seen three of its eight games go over the point total.

Arizona vs Colorado Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Wildcats win (63.2%)

Arizona vs Colorado Point Spread

Colorado is the underdog by 3.5 points against Arizona. Colorado is -115 to cover the spread, and Arizona is -105.

Arizona vs Colorado Over/Under

Arizona versus Colorado on Nov. 1 has an over/under of 53.5 points, with the over -104 and the under -118.

Arizona vs Colorado Moneyline

Colorado is the underdog, +148 on the moneyline, while Arizona is a -176 favorite.

Arizona vs. Colorado Points Insights

Arizona vs. Colorado Game Info

• Game day: Saturday, November 1, 2025
• Game time: 7 p.m. ET
• TV channel: Fox Sports 1
• Location: Boulder, Colorado
• Stadium: Folsom Field

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Check out even more in-depth Arizona vs. Colorado analysis on FanDuel Research.