Angels vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for May 4

Odds updated as of 5:12 a.m.

In MLB action on Monday, the Los Angeles Angels play the Chicago White Sox.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info about this matchup.

Angels vs White Sox Game Info

• Los Angeles Angels (13-22) vs. Chicago White Sox (16-18)
• Date: Monday, May 4, 2026
• Time: 9:38 p.m. ET
• Venue: Angel Stadium -- Anaheim, California
• Coverage: ABTV and CHSN

Angels vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAA: (-162) | CHW: (+136)
• Spread: LAA: -1.5 (+128) | CHW: +1.5 (-154)
• Total: 7.5 -- Over: (-122) | Under: (+100)

Angels vs White Sox Probable Starting Pitchers

Probable Pitchers: José Soriano (Angels) - 5-1, 0.84 ERA vs Davis Martin (White Sox) - 4-1, 1.95 ERA

The Angels will give the nod to Jose Soriano (5-1) versus the White Sox and Davis Martin (4-1). Soriano's team is 6-1-0 against the spread in his starts this season. When Soriano starts a game and his team is the favorite on the moneyline, they have a record of 2-1. When Martin starts, the White Sox have gone 5-1-0 against the spread. The White Sox are 5-1 in Martin's six starts this season that they were the underdog on the moneyline.

Angels vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Angels win (55.6%)

Angels vs White Sox Moneyline

• The moneyline numbers for Angels vs. White Sox reveal Los Angeles as the favorite (-162) and Chicago as the underdog (+136) on the road.

Angels vs White Sox Spread

• The Angels are hosting the White Sox and are favored by 1.5 runs on the spread. The Angels are +128 to cover the runline, with the White Sox being -154.

Angels vs White Sox Over/Under

• The over/under for the Angels versus White Sox game on May 4 has been set at 7.5, with -122 odds on the over and +100 odds on the under.

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Angels vs White Sox Betting Trends

• The Angels have won in two of the five contests they have been named as odds-on favorites in this year.
• Los Angeles has not played a game this season with better moneyline odds than -162.
• Contests with the Angels have gone over the total set by oddsmakers in 16 of 34 chances this season.
• In 34 games with a line this season, the Angels have a mark of 17-17-0 against the spread.
• The White Sox have been the underdog on the moneyline 29 total times this season. They've gone 13-16 in those games.
• Chicago is 4-5 (winning 44.4% of its games) when it has played as a moneyline underdog of +136 or longer.
• In the 32 games bookmakers have set an over/under for the White Sox, they have combined with opponents to go over the total 17 times (17-15-0).
• The White Sox have collected an 18-14-0 record against the spread this season.

Angels Player Leaders

• Mike Trout has 31 hits and an OBP of .433, both of which lead Los Angeles hitters this season. He has a .258 batting average and a slugging percentage of .550.
• Among all qualified batters, he ranks 73rd in batting average, his on-base percentage ranks second, and he is 14th in slugging.
• Trout has recorded at least one hit in eight straight games. In his last 10 outings he is hitting .314 with a double, three home runs, 11 walks and five RBIs.
• Jorge Soler has five doubles, seven home runs and 15 walks. He's batting .239 and slugging .469 with an on-base percentage of .336.
• He ranks 105th in batting average, 81st in on-base percentage and 46th in slugging among qualifying hitters.
• Soler has picked up at least one hit in nine games in a row. During his last 10 games he is batting .270 with two doubles, two home runs, five walks and seven RBIs.
• Zach Neto is batting .216 with a .381 slugging percentage and 15 RBI this year.
• Nolan Schanuel has been key for Los Angeles with 31 hits, an OBP of .304 plus a slugging percentage of .368.
• Schanuel has hit safely in three games in a row. During his last five outings he is batting .353 with a double.

White Sox Player Leaders

• Miguel Vargas is batting .220 with four doubles, a triple, six home runs and 24 walks. He's slugging .424 with an on-base percentage of .359.
• Including all qualifying hitters, he is 133rd in batting average, while his on-base percentage ranks 52nd and he is 70th in slugging.
• Vargas hopes to build on a six-game hitting streak in this matchup. During his last 10 games he is batting .286 with a double, a home run, eight walks and five RBIs.
• Munetaka Murakami paces his team with 27 hits and a .362 OBP. He has a batting average of .223 while slugging .545.
• His batting average is 129th among all qualified players, his on-base percentage ranks 47th, and he is 16th in slugging.
• Colson Montgomery is batting .227 with five doubles, nine home runs and 14 walks.
• Chase Meidroth paces his team with a .350 slugging percentage.

Angels vs White Sox Head to Head

• 4/29/2026: 3-2 CHW (Favorite: Angels, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 4/28/2026: 5-2 CHW (Favorite: Angels, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/3/2025: 8-5 LAA (Favorite: Angels, Spread: -1.5, Total: 9.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/2/2025: 1-0 CHW (Favorite: Angels, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 8/1/2025: 6-3 CHW (Favorite: Angels, Spread: -1.5, Total: 9, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 3/30/2025: 3-2 LAA (Favorite: Angels, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 3/29/2025: 1-0 LAA (Favorite: Angels, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 3/27/2025: 8-1 CHW (Favorite: Angels, Spread: -1.5, Total: 7.5, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 9/26/2024: 7-0 CHW (Favorite: Angels, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 9/25/2024: 4-3 CHW (Favorite: Angels, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)

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