Angels vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for April 22

Odds updated as of 9:11 p.m.

The Los Angeles Angels versus the Pittsburgh Pirates is on the MLB schedule for Tuesday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information about this matchup.

Angels vs Pirates Game Info

• Los Angeles Angels (11-10) vs. Pittsburgh Pirates (8-15)
• Date: Tuesday, April 22, 2025
• Time: 9:38 p.m. ET
• Venue: Angel Stadium -- Anaheim, California
• Coverage: FDSW and SportsNet PT

Angels vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAA: (-190) | PIT: (+160)
• Spread: LAA: -1.5 (+110) | PIT: +1.5 (-132)
• Total: 8.5 -- Over: (-120) | Under: (-102)

Angels vs Pirates Probable Starting Pitchers

Probable Pitchers: José Soriano (Angels) - 2-2, 3.16 ERA vs Bailey Falter (Pirates) - 1-2, 4.91 ERA

The probable pitchers are Jose Soriano (2-2) for the Angels and Bailey Falter (1-2) for the Pirates. Soriano's team is 1-3-0 against the spread in his starts this season. Soriano's team is 1-1 this season when he starts and they're favored on the moneyline. The Pirates have a 1-3-0 record against the spread in Falter's starts. The Pirates were named the moneyline underdog for two Falter starts this season -- they lost both.

Angels vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Angels win (55.7%)

Angels vs Pirates Moneyline

• Los Angeles is a -190 favorite on the moneyline, while Pittsburgh is a +160 underdog on the road.

Angels vs Pirates Spread

• The Angels are favored by 1.5 runs at home versus the Pirates. The Angels are +110 to cover the spread, while the Pirates are -132.

Angels vs Pirates Over/Under

• The Angels-Pirates contest on April 22 has been given an over/under of 8.5 runs. The over is set at -120 and the under at -102.

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Angels vs Pirates Betting Trends

• The Angels have been chosen as favorites in five games this year and have walked away with the win three times (60%) in those games.
• Oddsmakers have given Los Angeles the best odds of winning it has seen this season, with a -190 moneyline listed for this contest.
• The Angels' games have gone over the total in 10 of their 21 opportunities.
• The Angels are 11-10-0 against the spread in their 21 games with a line set by sportsbooks this season.
• The Pirates have won 25% of the games this season they were the underdog on the moneyline (3-9).
• Pittsburgh has never played a game this season with moneyline odds of +160 or longer.
• In the 23 games oddsmakers have set an over/under for the Pirates, they have combined with opponents to go over the total 10 times (10-12-1).
• The Pirates have a 7-16-0 record against the spread this season (covering just 30.4% of the time).

Angels Player Leaders

• Mike Trout is batting .184 with a double, eight home runs and 11 walks. He has an on-base percentage of .289 and a slugging percentage of .513.
• Among qualifying hitters, he ranks 150th in batting average, his on-base percentage ranks 121st, and he is 30th in slugging.
• Nolan Schanuel leads the Angels with an OPS of .777. He has a slash line of .273/.349/.429 this season.
• Among qualified batters, his batting average ranks him 62nd, his on-base percentage 62nd, and his slugging percentage 70th.
• Kyren Paris is batting .288 with a .635 slugging percentage and eight RBI this year.
• Taylor Ward is batting .216 with a .247 OBP and eight RBI for Los Angeles this season.

Pirates Player Leaders

• Oneil Cruz has racked up 15 hits with a .354 on-base percentage, leading the Pirates in both categories. He's batting .227 and slugging .485.
• Including all qualified players, he is 106th in batting average, while his on-base percentage is 54th and he is 43rd in slugging.
• Ke'Bryan Hayes has a double, a triple, a home run and seven walks while batting .211. He's slugging .289 with an on-base percentage of .277.
• He ranks 123rd in batting average, 125th in on-base percentage and 153rd in slugging percentage in the majors.
• Enmanuel Valdez is batting .229 with three doubles, two triples, a home run and eight walks.
• Isiah Kiner-Falefa has two doubles, a triple and five walks while batting .268.

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