76ers vs. Pistons Prediction, Odds, Picks, Best Bets for April 4

76ers vs. Pistons Game Info

• Date: Saturday, April 4, 2026
• Time: 7 p.m. ET
• Venue: Xfinity Mobile Arena -- Philadelphia, Pennsylvania
• Coverage: FDSDET, NBCS-PH, NBA TV, and WMYD

The Detroit Pistons (56-21) take on the Philadelphia 76ers (43-34) as just 2.5-point favorites on Saturday, April 4, 2026 at 7 p.m. ET on FDSDET, NBCS-PH, NBA TV, and WMYD. The matchup's point total is set at 225.5.

76ers vs. Pistons Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

76ers vs. Pistons Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Pistons win (68.7%)

76ers vs. Pistons Betting Trends

• The Pistons have compiled a 41-33-2 record against the spread this season.
• The 76ers are 39-36-2 against the spread this year.
• Pistons games have finished with a final combined score above the over/under 37 times this season.
• 76ers games this year have hit the over on 40 of 77 set point totals (51.9%).
• Against the spread, Detroit has performed worse when playing at home, covering 20 times in 40 home games, and 21 times in 37 road games.
• When playing at home, the Pistons exceed the over/under 47.5% of the time (19 of 40 games). They hit the over more consistently in road games, eclipsing the total in 48.6% of games (18 of 37).
• Against the spread, Philadelphia has had better results away (22-15-1) than at home (17-21-1).
• 76ers games have gone above the over/under less frequently at home (19 times out of 39) than away (21 of 38) this season.

Pistons Leaders

• Jalen Duren's numbers on the season are 19.5 points, 10.7 rebounds and 1.9 assists per game, shooting 64.5% from the floor (third in league).
• Ausar Thompson is averaging 9.9 points, 5.8 boards and 3 assists. Defensively, he averages 2 steals (first in NBA) and 0.9 blocked shots.
• Tobias Harris averages 13.1 points, 5.2 boards and 2.6 assists, shooting 46.2% from the floor and 34.9% from beyond the arc, with 1.3 made 3-pointers per game.
• Duncan Robinson is averaging 12.1 points, 2.7 rebounds and 2.1 assists. At the other end, he averages 0.6 steals and 0.3 blocked shots.
• Kevin Huerter is averaging 10 points, 3.5 boards and 2.5 assists. At the other end, he averages 0.8 steals and 0.5 blocked shots.

76ers Leaders

• Tyrese Maxey averages 28.7 points, 4.2 rebounds and 6.8 assists. He is also sinking 46.3% of his shots from the field and 37% from beyond the arc, with 3.2 triples per contest (seventh in league).
• The 76ers receive 16 points per game from VJ Edgecombe, plus 5.5 rebounds and 4.1 assists.
• The 76ers get 13.7 points per game from Quentin Grimes, plus 3.7 boards and 3.4 assists.
• Per game, Joel Embiid gives the 76ers 26.7 points, 7.6 boards and 4 assists, plus 0.6 steals and 1.1 blocks.
• Dominick Barlow averages 7.9 points, 4.8 rebounds and 1.3 assists. He is sinking 54.5% of his shots from the field.

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