2025 San Francisco 49ers Schedule, Results, TV Channel

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2025 San Francisco 49ers Schedule, Results, TV Channel

The San Francisco 49ers face a tough test on Oct. 12, when they square off against the Tampa Bay Buccaneers as part of their 2025 schedule. Details on the 49ers' full NFL schedule can be found below. For info on the San Francisco 49ers, including their 2025 results, NFL schedule, and where they sit in the NFC West, read the below article.

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49ers' 2025 Schedule

Date/Time	Opponent	Odds/Score	Location	TV Channel
Sunday, Sept. 7 at 4:05 p.m. ET	@ Seahawks	-	Lumen Field, Seattle, Washington	FOX
Sunday, Sept. 14 at 1 p.m. ET	@ Saints	-	Caesars Superdome, New Orleans, Louisiana	FOX
Sunday, Sept. 21 at 4:25 p.m. ET	Cardinals	-	Levi's Stadium, Santa Clara, California	FOX
Sunday, Sept. 28 at 4:05 p.m. ET	Jaguars	-	Levi's Stadium, Santa Clara, California	FOX
Thursday, Oct. 2 at 8:15 p.m. ET	@ Rams	-	SoFi Stadium, Inglewood, California	Amazon Prime Video
Sunday, Oct. 12 at 1 p.m. ET	@ Buccaneers	-	Raymond James Stadium, Tampa, Florida	CBS
Sunday, Oct. 19 at 8:20 p.m. ET	Falcons	-	Levi's Stadium, Santa Clara, California	NBC

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