Yankees vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for June 21

Odds updated as of 1:12 p.m.

The Sunday schedule in MLB includes a matchup between the New York Yankees and the Cincinnati Reds.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Yankees vs Reds Game Info

• New York Yankees (46-29) vs. Cincinnati Reds (36-39)
• Date: Sunday, June 21, 2026
• Time: 1:35 p.m. ET
• Venue: Yankee Stadium -- The Bronx, New York
• Coverage: YES and Reds.TV

Yankees vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-112) | CIN: (-104)
• Spread: NYY: +1.5 (-188) | CIN: -1.5 (+155)
• Total: 8.5 -- Over: (-124) | Under: (+102)

Yankees vs Reds Probable Starting Pitchers

Probable Pitchers: Elmer Rodriguez-Cruz (Yankees) - 0-1, 4.15 ERA vs Chase Burns (Reds) - 8-1, 2.01 ERA

The Yankees will give the nod to Elmer Rodriguez-Cruz (0-1) versus the Reds and Chase Burns (8-1). Rodriguez-Cruz's team is 1-2-0 against the spread this season in his starts. Rodriguez-Cruz's team is 1-1 this season when he starts and they're favored on the moneyline. When Burns starts, the Reds are 10-4-0 against the spread. The Reds have a 2-1 record in Burns' three starts this season when they were the moneyline underdog.

Yankees vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (55%)

Yankees vs Reds Moneyline

• The moneyline numbers for Yankees vs. Reds reveal New York as the favorite (-112) and Cincinnati as the underdog (-104) on the road.

Yankees vs Reds Spread

• The Reds are 1.5-run favorites against the spread for this matchup with the Yankees. The Reds are +155 to cover, while the Yankees are -188 to cover as a 1.5-run underdog on the runline.

Yankees vs Reds Over/Under

• A combined run total of 8.5 has been set for Yankees-Reds on June 21, with the over at -124 and the under at +102.

Bet on New York Yankees vs. Cincinnati Reds on FanDuel today!

Yankees vs Reds Betting Trends

• The Yankees have come away with 41 wins in the 65 contests they have been listed as the favorites in this season.
• New York has a record of 41-24 when favored by -112 or more this year.
• The Yankees and their opponents have gone over the total this season in 34 of their 72 opportunities.
• In 72 games with a line this season, the Yankees have a mark of 37-35-0 against the spread.
• The Reds have won 47.9% of the games this season they were the moneyline underdog (23-25).
• Cincinnati has a record of 20-24 when it has played as a moneyline underdog with odds of -104 or longer (45.5%).
• The Reds have had an over/under set by oddsmakers 73 times, and have combined with opponents to go over the total in 44 of those games (44-28-1).
• The Reds have gone 40-33-0 ATS this season.

Yankees Player Leaders

• Ben Rice leads New York in OBP (.383), slugging percentage (.604) and total hits (75) this season. He has a .288 batting average.
• Among qualified hitters, he is 19th in batting average, his on-base percentage ranks 13th, and he is second in slugging.
• Cody Bellinger has hit 11 homers this season while driving in 49 runs. He's batting .276 this season and slugging .474 with an on-base percentage of .369.
• Among all qualifying players, he ranks 42nd in batting average, 28th in on-base percentage and 36th in slugging percentage.
• Jazz Chisholm is batting .226 with a .409 slugging percentage and 31 RBI this year.
• Paul Goldschmidt is batting .291 with a .354 OBP and 37 RBI for New York this season.

Reds Player Leaders

• Sal Stewart has accumulated a .346 on-base percentage and a .457 slugging percentage, both team-best numbers for the Reds. He's batting .252.
• Including all qualifying hitters, he ranks 77th in batting average, while his on-base percentage is 57th and he is 53rd in slugging.
• Spencer Steer has 12 doubles, 12 home runs and 29 walks while hitting .240. He's slugging .429 with an on-base percentage of .323.
• He is 102nd in batting average, 92nd in on-base percentage and 77th in slugging percentage in the majors.
• JJ Bleday has 11 doubles, a triple, 13 home runs and 28 walks while hitting .259.
• Matt McLain has 13 doubles, eight home runs and 34 walks while hitting .204.

Yankees vs Reds Head to Head

• 6/20/2026: 10-2 CIN (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 6/19/2026: 5-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -275, Underdog Moneyline: +225)
• 6/25/2025: 7-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 6/24/2025: 5-4 CIN (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 6/23/2025: 6-1 CIN (Favorite: Yankees, Spread: -1.5, Total: 10, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/4/2024: 8-4 CIN (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 7/3/2024: 3-2 CIN (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 7/2/2024: 5-4 CIN (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 5/21/2023: 4-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 5/20/2023: 7-4 NYY (Favorite: Yankees, Spread: -1.5, Total: 10.5, Favorite Moneyline: -148, Underdog Moneyline: +126)

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