Yankees vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for May 5

Odds updated as of 6:11 p.m.

MLB action on Monday includes the New York Yankees facing the San Diego Padres.

All the information you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Yankees vs Padres Game Info

• New York Yankees (19-15) vs. San Diego Padres (22-11)
• Date: Monday, May 5, 2025
• Time: 7:05 p.m. ET
• Venue: Yankee Stadium -- The Bronx, New York
• Coverage: MLB Network, YES, and SDPA

Yankees vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-162) | SD: (+136)
• Spread: NYY: -1.5 (+132) | SD: +1.5 (-160)
• Total: 8 -- Over: (-102) | Under: (-120)

Yankees vs Padres Probable Starting Pitchers

Probable Pitchers: Carlos Rodon (Yankees) - 4-3, 3.43 ERA vs Nicholas Pivetta (Padres) - 5-1, 1.78 ERA

This contest's pitching matchup is set, as the Yankees will send Carlos Rodon (4-3) to the mound, while Nicholas Pivetta (5-1) will take the ball for the Padres. Rodon's team is 3-4-0 against the spread in his starts this season. Rodon's team is 4-3 this season when he starts and they are the moneyline favorite. The Padres are 5-1-0 ATS in Pivetta's six starts with a set spread. The Padres are 2-1 in Pivetta's three starts this season that they were the underdog on the moneyline.

Yankees vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (53.7%)

Yankees vs Padres Moneyline

• Looking at the moneyline for Padres-Yankees, San Diego is the underdog at +136, and New York is -162 playing at home.

Yankees vs Padres Spread

• The Padres are +1.5 on the run line against the Yankees. The Padres are -160 to cover, and the Yankees are +132.

Yankees vs Padres Over/Under

• A combined run total of 8 has been set for Yankees-Padres on May 5, with the over at -102 and the under at -120.

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Yankees vs Padres Betting Trends

• The Yankees have been chosen as favorites in 27 games this year and have walked away with the win 17 times (63%) in those games.
• New York has a record of 9-3 in contests when sportsbooks favor them by -162 or more on the moneyline.
• The Yankees and their opponents have gone over in 15 of their 33 games with a total set by sportsbooks this season.
• The Yankees have posted a record of 16-17-0 against the spread this season.
• The Padres have won 50% of the games this season they were the moneyline underdog (7-7).
• San Diego has played as a moneyline underdog of +136 or longer in only one game this season, which it lost.
• The Padres have combined with opponents to go over the total 13 times this season for a 13-18-1 record against the over/under.
• The Padres are 19-13-0 against the spread this season.

Yankees Player Leaders

• Aaron Judge has 55 hits and an OBP of .510 to go with a slugging percentage of .777. All three of those stats are best among New York hitters this season. He has a .423 batting average, as well.
• Among all qualifying batters in baseball, he ranks first in batting average, first in on-base percentage, and first in slugging.
• Judge will look for his 15th straight game with a hit in this contest. In his last 10 outings he is batting .450 with two doubles, two triples, four home runs, five walks and eight RBI.
• Paul Goldschmidt is hitting .349 with eight doubles, three home runs and 10 walks, while slugging .481 with an on-base percentage of .397.
• Among qualifying batters, his batting average ranks him second, his on-base percentage 11th, and his slugging percentage 36th.
• Ben Rice has 26 hits this season and has a slash line of .255/.361/.559.
• Anthony Volpe has five home runs, 19 RBI and a batting average of .233 this season.

Padres Player Leaders

• Fernando Tatis Jr. has put up a team-best OBP (.399) and slugging percentage (.574), and paces the Padres in hits (40, while batting .328).
• Including all the qualified players in MLB, he ranks seventh in batting average, eighth in on-base percentage and eighth in slugging percentage.
• Manny Machado has 11 doubles, three home runs and 13 walks while hitting .295. He's slugging .459 with an on-base percentage of .360.
• Including all qualifying hitters, he is 23rd in batting average, 42nd in on-base percentage and 49th in slugging percentage.
• Luis Arraez is hitting .306 with four doubles, a triple, three home runs and five walks.
• Xander Bogaerts has nine doubles, a home run and 15 walks while batting .243.

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