White Sox vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 11

Odds updated as of 2:12 a.m.

MLB action on Tuesday includes the Chicago White Sox facing the Cincinnati Reds.

All the info you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

White Sox vs Reds Game Info

• Chicago White Sox (61-56) vs. Cincinnati Reds (56-61)
• Date: Tuesday, August 11, 2026
• Time: 7:40 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and Reds.TV

White Sox vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHW: (-166) | CIN: (+140)
• Spread: CHW: -1.5 (+128) | CIN: +1.5 (-154)
• Total: 8.5 -- Over: (+102) | Under: (-124)

White Sox vs Reds Probable Starting Pitchers

Probable Pitchers: Sean Burke (White Sox) - 7-6, 3.08 ERA vs Nick Lodolo (Reds) - 3-2, 4.60 ERA

The White Sox will call on Sean Burke (7-6) versus the Reds and Nick Lodolo (3-2). Burke and his team are 9-10-0 ATS this season when he starts. Burke's team has a record of 4-1 this season when he starts and they are the favorite on the moneyline. The Reds have gone 5-7-0 against the spread when Lodolo starts. The Reds have a 3-4 record in Lodolo's seven starts this season when they were the moneyline underdog.

White Sox vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: White Sox win (61%)

White Sox vs Reds Moneyline

• The moneyline numbers for White Sox vs. Reds reveal Chicago as the favorite (-166) and Cincinnati as the underdog (+140) on the road.

White Sox vs Reds Spread

• The White Sox are favored by 1.5 runs at home versus the Reds. The White Sox are +128 to cover the spread, while the Reds are -154.

White Sox vs Reds Over/Under

• The White Sox-Reds game on Aug. 11 has been given an over/under of 8.5 runs. The over is set at +102 and the under at -124.

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White Sox vs Reds Betting Trends

• The White Sox have come away with 13 wins in the 21 contests they have been listed as the favorites in this season.
• Chicago has been listed as a favorite of -166 or more on two occasions this season and won both games.
• The White Sox and their opponents have gone over the total this season in 63 of their 114 opportunities.
• The White Sox are 67-47-0 against the spread in their 114 games with a line set by sportsbooks this season.
• The Reds have won 48% of the games this season they were the moneyline underdog (36-39).
• Cincinnati has a record of 4-6 when it has played as a moneyline underdog with odds of +140 or longer (40%).
• The Reds have had an over/under set by oddsmakers 114 times, and have combined with opponents to go over the total in 60 of those games (60-52-2).
• The Reds have covered 52.6% of their games this season, going 60-54-0 against the spread.

White Sox Player Leaders

• Miguel Vargas has 101 hits, which leads Chicago hitters this season, while batting .235 with 51 extra-base hits. He has an on-base percentage of .343 and a slugging percentage of .467.
• Among qualifying hitters, he is 111th in batting average, his on-base percentage ranks 52nd, and he is 35th in slugging.
• Vargas hopes to build on a two-game hitting streak in this matchup. During his last five outings he is hitting .211 with a double and five walks.
• Chase Meidroth has an OPS of .754, fueled by an OBP of .350 and a team-best slugging percentage of .404 this season. He's batting .274.
• He ranks 33rd in batting average, 45th in on-base percentage and 93rd in slugging in the majors.
• Meidroth brings a three-game streak with at least one hit into this one. During his last five outings he is hitting .300 with a double, two home runs, three walks and six RBIs.
• Munetaka Murakami has collected 70 base hits, an OBP of .370 and a slugging percentage of .539 this season.
• Murakami brings a three-game hitting streak into this matchup. In his last five games he is batting .150 with a double, two home runs, four walks and three RBIs.
• Sam Antonacci leads Chicago with an OBP of .366 this season while batting .273 with 28 walks and 59 runs scored.

Reds Player Leaders

• Sal Stewart has a .475 slugging percentage, which paces the Reds. He's batting .255 with an on-base percentage of .332.
• Including all the qualified hitters in the big leagues, he is 72nd in batting average, 75th in on-base percentage and 29th in slugging percentage.
• Elly De La Cruz leads his team with 105 hits and a .353 OBP. He has a batting average of .271 while slugging .499.
• He ranks 41st in batting average, 39th in on-base percentage and 16th in slugging percentage in the big leagues.
• JJ Bleday is batting .225 with 12 doubles, a triple, 20 home runs and 53 walks.
• Tyler Stephenson is hitting .248 with 16 doubles, 10 home runs and 35 walks.

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