White Sox vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for April 26

Odds updated as of 1:11 p.m.

The Chicago White Sox are among the MLB squads in action on Sunday, up against the Washington Nationals.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

White Sox vs Nationals Game Info

• Chicago White Sox (11-16) vs. Washington Nationals (12-16)
• Date: Sunday, April 26, 2026
• Time: 2:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and Nationals.TV

White Sox vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHW: (-120) | WSH: (+102)
• Spread: CHW: +1.5 (-205) | WSH: -1.5 (+168)
• Total: 7.5 -- Over: (-104) | Under: (-118)

White Sox vs Nationals Probable Starting Pitchers

Probable Pitchers: Bryan Hudson (White Sox) - 0-0, 1.54 ERA vs Foster Griffin (Nationals) - 3-0, 3.37 ERA

This contest's pitching matchup is set, as the White Sox will send Bryan Hudson to the mound, while Foster Griffin (3-0) will take the ball for the Nationals. Hudson helped his team cover the spread in his only opportunity this season as a starter. Hudson's team won his only start as a favorite this season. The Nationals have gone 4-1-0 ATS in Griffin's five starts with a set spread. The Nationals have a 4-1 record in Griffin's five starts this season when they were the moneyline underdog.

White Sox vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: White Sox win (56.6%)

White Sox vs Nationals Moneyline

• The White Sox vs Nationals moneyline has Chicago as a -120 favorite, while Washington is a +102 underdog on the road.

White Sox vs Nationals Spread

• The Nationals are 1.5-run favorites against the spread for this matchup with the White Sox. The Nationals are +168 to cover, while the White Sox are -205 to cover as a 1.5-run underdog on the runline.

White Sox vs Nationals Over/Under

• A total of 7.5 runs has been set for the White Sox-Nationals contest on April 26, with the over available at -104 and the under at -118.

Bet on Chicago White Sox vs. Washington Nationals on FanDuel today!

White Sox vs Nationals Betting Trends

• The White Sox have split the two match ups they have played as odds-on favorites this season.
• Chicago has been listed as a favorite of -120 or more on two occasions this season and split those games.
• Contests with the White Sox have gone over the total set by bookmakers in 16 of 26 chances this season.
• The White Sox have an against the spread mark of 12-14-0 in 26 games with a line this season.
• The Nationals have been the moneyline underdog 27 total times this season. They've gone 12-15 in those games.
• Washington has an 11-14 record (winning 44% of its games) when playing as a moneyline underdog of +102 or longer.
• In the 28 games bookmakers have set an over/under for the Nationals, they have combined with opponents to go over the total 19 times (19-8-1).
• The Nationals have gone 16-12-0 against the spread this season.

White Sox Player Leaders

• Miguel Vargas is hitting .213 with four doubles, a triple, five home runs and 19 walks. He has an on-base percentage of .353 while slugging .436.
• Among all qualifying hitters in MLB, his batting average ranks 141st, his on-base percentage ranks 57th, and he is 61st in slugging.
• Vargas has picked up at least one hit in six games in a row. During his last 10 games he is batting .275 with a double, four home runs, nine walks and six RBIs.
• Munetaka Murakami has 23 hits and an OBP of .381, both of which lead the White Sox this season. He's batting .242 and slugging .589.
• Among all qualifying players, he ranks 93rd in batting average, 22nd in on-base percentage and sixth in slugging percentage.
• Colson Montgomery is batting .232 with a .505 slugging percentage and 19 RBI this year.
• Chase Meidroth leads Chicago with a slugging percentage of .351, fueled by six extra-base hits.

Nationals Player Leaders

• James Wood has racked up a team-best OBP (.401), and paces the Nationals in hits (26). He's batting .241 and slugging.
• Including all the qualifying hitters in the majors, he is 96th in batting average, 14th in on-base percentage and eighth in slugging percentage.
• C.J. Abrams has three doubles, seven home runs and 13 walks while hitting .277. He's slugging .532 with an on-base percentage of .395.
• Including all qualified hitters, his batting average places him 48th, his on-base percentage is 18th, and he is 18th in slugging.
• Daylen Lile has accumulated a slugging percentage of .432, a team-best for the Nationals.
• Luis Garcia is batting .264 with five doubles, a triple, a home run and four walks.

White Sox vs Nationals Head to Head

• 4/25/2026: 6-3 WSH (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 4/24/2026: 5-4 CHW (Favorite: White Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/28/2025: 8-0 CHW (Favorite: Nationals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/27/2025: 6-5 WSH (Favorite: Nationals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 9/26/2025: 10-9 CHW (Favorite: Nationals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/15/2024: 2-0 CHW (Favorite: White Sox, Spread: -1.5, Total: 7, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 5/14/2024: 4-0 CHW (Favorite: Nationals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/14/2024: 6-3 WSH (Favorite: Nationals, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/20/2023: 13-3 WSH (Favorite: Nationals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 9/19/2023: 4-3 WSH (Favorite: Nationals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -118, Underdog Moneyline: -100)

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