White Sox vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for July 26

Odds updated as of 2:12 p.m.

Sunday's slate in the MLB includes a matchup between the Chicago White Sox and the Houston Astros.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info about this matchup.

White Sox vs Astros Game Info

• Chicago White Sox (54-49) vs. Houston Astros (52-54)
• Date: Sunday, July 26, 2026
• Time: 2:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and SCHN

White Sox vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHW: (-110) | HOU: (-106)
• Spread: CHW: +1.5 (-188) | HOU: -1.5 (+155)
• Total: 9 -- Over: (-114) | Under: (-106)

White Sox vs Astros Probable Starting Pitchers

Probable Pitchers: Erick Fedde (White Sox) - 5-6, 4.16 ERA vs Ronel Blanco (Astros) - 0-0, 7.71 ERA

The White Sox will give the nod to Erick Fedde (5-6, 4.16 ERA), who is eyeing win No. 6 on the season, and the Astros will turn to Ronel Blanco. Fedde and his team are 7-3-0 ATS this season when he starts. Fedde has yet to start a game this season when his team was the moneyline favorite. Blanco has started only one game with a set spread, which the Astros covered. The Astros have not been a moneyline underdog when Blanco starts this season.

White Sox vs Astros Moneyline

• The moneyline numbers for White Sox vs. Astros reveal Chicago as the favorite (-110) and Houston as the underdog (-106) on the road.

White Sox vs Astros Spread

• The Astros are 1.5-run favorites against the spread for this matchup with the White Sox. The Astros are +155 to cover, while the White Sox are -188 to cover as a 1.5-run underdog on the runline.

White Sox vs Astros Over/Under

• White Sox versus Astros on July 26 has an over/under of 9 runs, with the odds on the over -114 and the under set at -106.

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White Sox vs Astros Betting Trends

• The White Sox have won in 11, or 57.9%, of the 19 contests they have been named as odds-on favorites in this year.
• This season Chicago has come away with a win 11 times in 19 chances when named as a favorite of at least -110 on the moneyline.
• The White Sox and their opponents have gone over in 55 of their 100 games with a total set by sportsbooks this season.
• The White Sox have an against the spread record of 57-43-0 in 100 games with a line this season.
• The Astros have a 32-30 record in games they were listed as the moneyline underdog (winning 51.6% of those games).
• Houston has a record of 32-29 when it has played as a moneyline underdog with odds of -106 or longer (52.5%).
• In the 106 games bookmakers have set an over/under for the Astros, they have combined with opponents to go over the total 55 times (55-47-4).
• The Astros have a 52-54-0 record ATS this season (covering 49.1% of the time).

White Sox Player Leaders

• Miguel Vargas leads Chicago in total hits (91) this season while batting .243 with 46 extra-base hits. He has an on-base percentage of .350 and a slugging percentage of .480.
• Among all qualified hitters in baseball, his batting average ranks 97th, his on-base percentage ranks 49th, and he is 32nd in slugging.
• Sam Antonacci has 81 hits this season and a team-best OBP of .370. He's batting .278 and slugging .409.
• Among all qualified, he is 34th in batting average, 19th in on-base percentage and 90th in slugging percentage.
• Colson Montgomery is batting .218 with a .460 slugging percentage and 59 RBI this year.
• Chase Meidroth has an OPS of .727, fueled by an OBP of .346 and a team-best slugging percentage of .381 this season.

Astros Player Leaders

• Yordan Alvarez has totaled 123 hits with a .431 on-base percentage and a .646 slugging percentage, all club-bests for the Astros. He's batting .325.
• Including all qualifying hitters in the majors, he ranks third in batting average, first in on-base percentage and first in slugging percentage.
• Isaac Paredes is hitting .263 with 18 doubles, a triple, 14 home runs and 40 walks. He's slugging .435 with an on-base percentage of .356.
• He ranks 60th in batting average, 37th in on-base percentage and 67th in slugging percentage in the majors.
• Christian Walker is hitting .232 with 20 doubles, a triple, 20 home runs and 34 walks.
• Jeremy Pena is hitting .315 with nine doubles, nine home runs and 17 walks.

White Sox vs Astros Head to Head

• 7/25/2026: 4-1 HOU (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/24/2026: 9-5 HOU (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/12/2025: 4-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -275, Underdog Moneyline: +225)
• 6/11/2025: 10-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 6/10/2025: 4-2 CHW (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 5/4/2025: 5-4 CHW (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 5/3/2025: 8-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 5/2/2025: 7-3 CHW (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 8/18/2024: 2-0 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -375, Underdog Moneyline: +300)
• 8/17/2024: 6-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -375, Underdog Moneyline: +300)

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