Western Kentucky vs Missouri State Prediction, Odds, Picks, Best Bets for Week 5 2025

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College football's Saturday schedule includes the Western Kentucky Hilltoppers taking on the Missouri State Bears.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Western Kentucky vs Missouri State Odds & Spread

All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
Moneyline: Western Kentucky: (-182) | Missouri State: (+150)
Spread: Western Kentucky: -4.5 (-105) | Missouri State: +4.5 (-115)
Total: 60.5 -- Over: (-110) | Under: (-110)

Against the spread, Western Kentucky is 3-1-0 this year.
Western Kentucky has yet to lose ATS (3-0) as a 4.5-point favorite or greater this year.
Western Kentucky has played four games this year, and three of them have gone over the total.
Against the spread, Missouri State is 3-1-0 this year.
Missouri State has two wins ATS (2-1) as a 4.5-point underdog or greater this year.
One of Missouri State's four games has gone over the point total.

All college football win probability predictions and picks are according to numberFire.
Prediction: Hilltoppers win (54.3%)

Missouri State is listed as an underdog by 4.5 points (-115 odds), and Western Kentucky, the favorite, is -105 to cover.

Western Kentucky versus Missouri State, on Sept. 27, has an over/under of 60.5, with the over being -110 and the under -110.

Looking at the moneyline for Western Kentucky-Missouri State, Western Kentucky is the favorite at -182, and Missouri State is +150.

	Point Scored (PG)	Points Scored CFB Rank	Points Allowed (PG)	Points Allowed CFB Rank	Average Total	Total Games
Western Kentucky	37.0	24	22.8	70	58.0	4
Missouri State	21.5	102	32.8	124	57.3	4

Check out even more in-depth Western Kentucky vs. Missouri State analysis on FanDuel Research.

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