Red Sox vs Tigers Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 27

Odds updated as of 11:11 a.m.

On Saturday in MLB, the Boston Red Sox are up against the Detroit Tigers.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Red Sox vs Tigers Game Info

• Boston Red Sox (88-72) vs. Detroit Tigers (86-74)
• Date: Saturday, September 27, 2025
• Time: 4:10 p.m. ET
• Venue: Fenway Park -- Boston, Massachusetts
• Coverage: NESN and FDSDET

Red Sox vs Tigers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-130) | DET: (+110)
• Spread: BOS: -1.5 (+160) | DET: +1.5 (-194)
• Total: 9 -- Over: (-100) | Under: (-122)

Red Sox vs Tigers Probable Starting Pitchers

Probable Pitchers: Connelly Early (Red Sox) - 1-1, 1.88 ERA vs Keider Montero (Tigers) - 5-3, 4.48 ERA

This contest's pitching matchup is set, as the Red Sox will send Connelly Early (1-1) to the mound, while Keider Montero (5-3) will get the nod for the Tigers. Early's team is 1-2-0 against the spread this season in his starts. Early's team is 0-2 this season when he starts and they're favored on the moneyline. The Tigers are 7-3-0 against the spread when Montero starts. The Tigers have been the underdog on the moneyline in three of Montero's starts this season, and they went 1-2 in those matchups.

Red Sox vs Tigers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (58.6%)

Red Sox vs Tigers Moneyline

• Looking at the moneyline for Tigers-Red Sox, Detroit is the underdog at +110, and Boston is -130 playing at home.

Red Sox vs Tigers Spread

• The Red Sox are hosting the Tigers and are favored by 1.5 runs on the spread. The Red Sox are +160 to cover the runline, with the Tigers being -194.

Red Sox vs Tigers Over/Under

• An over/under of 9 has been set for Red Sox-Tigers on Sept. 27, with the over being -100 and the under -122.

Bet on Boston Red Sox vs. Detroit Tigers on FanDuel today!

Red Sox vs Tigers Betting Trends

• The Red Sox have been favorites in 100 games this season and have come away with the win 58 times (58%) in those contests.
• Boston has a record of 33-26 when favored by -130 or more this year.
• The Red Sox's games have gone over the total in 74 of their 159 opportunities.
• In 159 games with a line this season, the Red Sox have a mark of 85-74-0 against the spread.
• The Tigers have won 21 of the 43 games they were the underdog on the moneyline this season (48.8%).
• In games it has played as a moneyline underdog with odds of +110 or longer, Detroit has a 9-11 record (winning 45% of its games).
• The Tigers have had an over/under set by bookmakers 153 times, and have combined with opponents to go over the total in 78 of those games (78-69-6).
• The Tigers have covered 46.4% of their games this season, going 71-82-0 ATS.

Red Sox Player Leaders

• Jarren Duran is hitting .257 with 40 doubles, 13 triples, 16 home runs and 60 walks. He has an on-base percentage of .333 while slugging .442.
• He ranks 77th in batting average, 65th in on-base percentage, and 63rd in slugging among all qualifying hitters in MLB.
• Duran will look for his third straight game with a hit in this contest. During his last five outings he is hitting .150 with a double, two walks and an RBI.
• Trevor Story has hit 25 homers this season while driving in 96 runs. He's batting .265 this season and slugging .436 with an on-base percentage of .310.
• Among qualifying hitters, he is 49th in batting average, 109th in on-base percentage and 70th in slugging percentage.
• Alex Bregman leads Boston with 118 hits and an OBP of .360 this season.
• Ceddanne Rafaela has 16 home runs, 63 RBI and a batting average of .247 this season.

Tigers Player Leaders

• Gleyber Torres has an on-base percentage of .361, a team-best for the Tigers. He's batting .258 and slugging .390.
• He ranks 74th in batting average, 19th in on-base percentage and 117th in slugging percentage among all qualified hitters in the big leagues.
• Torres hopes to build on a three-game hitting streak in this matchup. In his last five games he is hitting .227 with a double, a walk and an RBI.
• Riley Greene's 155 hits and .497 slugging percentage both pace his team. He has a batting average of .260 with an on-base percentage of .315.
• Including all qualified players, he is 68th in batting average, 104th in on-base percentage and 18th in slugging percentage.
• Spencer Torkelson is hitting .242 with 27 doubles, a triple, 31 home runs and 72 walks.
• Zach McKinstry has 23 doubles, 11 triples, 12 home runs and 46 walks while batting .261.

Red Sox vs Tigers Head to Head

• 9/26/2025: 4-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/14/2025: 6-5 DET (Favorite: Tigers, Spread: -1.5, Total: 7, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 5/13/2025: 10-9 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/12/2025: 14-2 DET (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/1/2024: 4-1 DET (Favorite: Tigers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 8/31/2024: 2-1 DET (Favorite: Tigers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 8/30/2024: 7-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/2/2024: 8-4 DET (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/1/2024: 6-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/31/2024: 7-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!