Twins vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for June 12

Odds updated as of 5:12 p.m.

On Friday in MLB, the Minnesota Twins are up against the St. Louis Cardinals.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Twins vs Cardinals Game Info

• Minnesota Twins (31-39) vs. St. Louis Cardinals (37-29)
• Date: Friday, June 12, 2026
• Time: 8:10 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: Twins.TV and Cardinals.TV

Twins vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-108) | STL: (-108)
• Spread: MIN: +1.5 (-184) | STL: -1.5 (+155)
• Total: 8.5 -- Over: (-122) | Under: (+100)

Twins vs Cardinals Probable Starting Pitchers

Probable Pitchers: Joe Ryan (Twins) - 4-3, 3.07 ERA vs Kyle Leahy (Cardinals) - 5-3, 4.42 ERA

This contest's pitching matchup is set, as the Twins will send Joe Ryan (4-3) to the mound, while Kyle Leahy (5-3) will take the ball for the Cardinals. Ryan and his team are 8-5-0 ATS this season when he starts. Ryan's team has been victorious in 55.6% of the games he's started as the moneyline favorite with a record of 5-4. When Leahy starts, the Cardinals have gone 6-5-0 against the spread. The Cardinals are 4-5 in Leahy's nine starts this season that they were the moneyline underdog.

Twins vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (55.4%)

Twins vs Cardinals Moneyline

• The moneyline numbers for Twins vs. Cardinals reveal Minnesota as the favorite (-108) and St. Louis as the underdog (-108) on the road.

Twins vs Cardinals Spread

Twins vs Cardinals Over/Under

• A total of 8.5 runs has been set for the Twins-Cardinals game on June 12, with the over available at -122 and the under at +100.

Bet on Minnesota Twins vs. St. Louis Cardinals on FanDuel today!

Twins vs Cardinals Betting Trends

• The Twins have won in 11, or 47.8%, of the 23 contests they have been named as odds-on favorites in this year.
• Minnesota has a record of 11-13 when favored by -108 or more this year.
• The Twins and their opponents have gone over in 42 of their 68 games with a total set by sportsbooks this season.
• In 68 games with a line this season, the Twins have a mark of 37-31-0 against the spread.
• The Cardinals have won 52.9% of the games this season they were the underdog on the moneyline (27-24).
• When playing as a moneyline underdog with odds of -108 or longer, St. Louis has a 27-24 record (winning 52.9% of its games).
• The Cardinals have had an over/under set by oddsmakers 65 times, and have combined with opponents to go over the total in 28 of those games (28-32-5).
• The Cardinals have gone 40-25-0 ATS this season.

Twins Player Leaders

• Byron Buxton leads Minnesota with 61 hits and a team-best slugging percentage of .559. He's batting .256 with an on-base percentage of .318.
• He is 72nd in batting average, 105th in on-base percentage, and sixth in slugging among qualified hitters in baseball.
• Brooks Lee is batting .238 with nine doubles, a triple, 10 home runs and 18 walks. He's slugging .410 with an on-base percentage of .296.
• He ranks 105th in batting average, 127th in on-base percentage and 85th in slugging in the majors.
• Josh Bell has 56 hits this season and has a slash line of .229/.285/.363.
• Bell enters this game with four games in a row with at least one hit. During his last five outings he is hitting .238 with two home runs and five RBIs.
• Luke Keaschall is batting .247 with a .323 OBP and 21 RBI for Minnesota this season.
• Keaschall enters this game on a three-game hitting streak. In his last five games he is batting .267 with a walk.

Cardinals Player Leaders

• Jordan Walker has a slugging percentage of .561 and has 77 hits, both team-best marks for the Cardinals. He's batting .302 and with an on-base percentage of .358.
• Including all the qualifying players in the big leagues, his batting average places him 14th, his on-base percentage ranks 41st, and he is fourth in slugging.
• Walker hopes to build on an eight-game hitting streak in this matchup. In his last 10 games he is hitting .356 with four doubles, two home runs and 10 RBIs.
• Alec Burleson has 17 doubles, 11 home runs and 25 walks while batting .290. He's slugging .486 with an on-base percentage of .356.
• Including all qualified hitters, he is 20th in batting average, 44th in on-base percentage and 35th in slugging percentage.
• Ivan Herrera a has .393 on-base percentage to pace the Cardinals.
• JJ Wetherholt is hitting .248 with seven doubles, nine home runs and 31 walks.

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