Tigers vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for May 20

Odds updated as of 6:11 a.m.

The MLB's Tuesday slate includes the Detroit Tigers facing the St. Louis Cardinals.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Tigers vs Cardinals Game Info

• Detroit Tigers (31-17) vs. St. Louis Cardinals (27-21)
• Date: Tuesday, May 20, 2025
• Time: 7:45 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: FDSMW and FDSDET

Tigers vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: DET: (-188) | STL: (+158)
• Spread: DET: -1.5 (-111) | STL: +1.5 (-108)
• Total: 7.5 -- Over: (-104) | Under: (-118)

Tigers vs Cardinals Probable Starting Pitchers

Probable Pitchers: Tarik Skubal (Tigers) - 4-2, 2.67 ERA vs Erick Fedde (Cardinals) - 3-3, 3.44 ERA

The Tigers will give the ball to Tarik Skubal (4-2, 2.67 ERA), who is eyeing win No. 5 on the season, and the Cardinals will counter with Erick Fedde (3-3, 3.44 ERA). Skubal's team is 5-4-0 against the spread this season in his starts. Skubal's team has been victorious in 75% of the games he's started as the moneyline favorite with a record of 6-2. The Cardinals have a 5-4-0 ATS record in Fedde's nine starts with a set spread. The Cardinals have a 2-4 record in Fedde's six starts this season when they were the moneyline underdog.

Tigers vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (56.5%)

Tigers vs Cardinals Moneyline

• Detroit is the favorite, -188 on the moneyline, while St. Louis is a +158 underdog despite being at home.

Tigers vs Cardinals Spread

• The Cardinals are +1.5 on the run line against the Tigers. The Cardinals are -108 to cover, and the Tigers are -111.

Tigers vs Cardinals Over/Under

• A combined run total of 7.5 has been set for Tigers-Cardinals on May 20, with the over at -104 and the under at -118.

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Tigers vs Cardinals Betting Trends

• The Tigers have been victorious in 20, or 74.1%, of the 27 contests they have been chosen as favorites in this season.
• Detroit has a record of 6-2 in contests when bookmakers favor them by -188 or more on the moneyline.
• The Tigers and their opponents have gone over the total this season in 24 of their 47 opportunities.
• The Tigers are 26-21-0 against the spread in their 47 games that had a posted line this season.
• The Cardinals have compiled an 18-14 record in games they were listed as the moneyline underdog (winning 56.2% of those games).
• St. Louis has played in three games as a moneyline underdog with odds of +158 or longer without claiming a victory.
• The Cardinals have had an over/under set by bookmakers 48 times, and have combined with opponents to go over the total in 25 of those games (25-21-2).
• The Cardinals have a 27-21-0 record ATS this season (covering 56.2% of the time).

Tigers Player Leaders

• Spencer Torkelson leads Detroit in total hits (41) this season while batting .246 with 24 extra-base hits. He has an on-base percentage of .352 and a slugging percentage of .533.
• Among all qualified batters in MLB, his batting average ranks 96th, his on-base percentage ranks 57th, and he is 14th in slugging.
• Torkelson hopes to build on a three-game hitting streak in this matchup. In his last five games he is batting .313 with a double, two home runs, four walks and five RBIs.
• Gleyber Torres has 38 hits this season and a team-best OBP of .368. He's batting .284 and slugging .440.
• His batting average ranks 38th among qualified players, his on-base percentage 38th, and his slugging percentage 66th.
• Riley Greene has an OPS of .836, fueled by an OBP of .328 and a team-best slugging percentage of .508 this season.
• Greene takes a two-game hitting streak into this game. During his last five outings he is hitting .400 with three doubles, two home runs, a walk and five RBIs.
• Kerry Carpenter is batting .284 with a .312 OBP and 21 RBI for Detroit this season.

Cardinals Player Leaders

• Lars Nootbaar has 10 doubles, seven home runs and 31 walks while hitting .258. He's slugging .425 with an on-base percentage of .364.
• Including all the qualified players in the big leagues, his batting average places him 75th, his on-base percentage ranks 44th, and he is 77th in slugging.
• Brendan Donovan's 61 hits, .392 OBP and .475 slugging percentage all pace his team. He has a batting average of .337.
• His batting average is sixth among all qualified players, his on-base percentage is 12th, and he is 41st in slugging.
• Nolan Arenado is hitting .241 with 10 doubles, four home runs and 17 walks.
• Willson Contreras has nine doubles, six home runs and 16 walks while batting .249.

Tigers vs Cardinals Head to Head

• 5/19/2025: 11-4 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 5/1/2024: 4-1 DET (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/30/2024: 11-6 DET (Favorite: Tigers, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/30/2024: 2-1 STL (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/7/2023: 12-6 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 5/6/2023: 6-5 DET (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 5/5/2023: 5-4 DET (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -240, Underdog Moneyline: +198)

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