Spurs vs. Timberwolves Western Semifinals Prediction, Odds, Picks, Best Bets for May 6

Spurs vs. Timberwolves Game Info

• Date: Wednesday, May 6, 2026
• Time: 9:30 p.m. ET
• Venue: Frost Bank Center -- San Antonio, Texas
• Coverage: ESPN

The Minnesota Timberwolves are big 10.5-point underdogs in Game 2 of the second round of the NBA Playoffs against the San Antonio Spurs at Frost Bank Center on Wednesday, starting at 9:30 p.m. ET on ESPN. The Timberwolves hold a 1-0 lead in the series. The point total is 216.5 for the matchup.

Spurs vs. Timberwolves Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Spurs vs. Timberwolves Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Spurs win (70.4%)

Spurs vs. Timberwolves Betting Trends

• The Spurs have gone 43-34-4 against the spread this season.
• Against the spread, the Timberwolves are 38-44-0 this season.
• This season, Spurs games have hit the over 36 times.
• The Timberwolves have hit the over 45.1% of the time this season (37 of 82 games with a set point total).
• San Antonio has covered the spread in a lower percentage of its home games than road games. It has covered 19 times in 40 games at home, and it has covered 24 times in 42 games on the road.
• In terms of over/unders, the Spurs hit the over more consistently when playing at home, as they've eclipsed the total 18 times in 40 opportunities this season (45%). On the road, they have hit the over 18 times in 42 opportunities (42.9%).
• This season, Minnesota is 18-23-0 at home against the spread (.439 winning percentage). On the road, it is 20-21-0 ATS (.488).
• Timberwolves games have finished above the over/under less often at home (14 times out of 41) than on the road (23 of 41) this season.

Spurs Leaders

• Victor Wembanyama is averaging 25 points, 3.1 assists and 11.5 rebounds.
• De'Aaron Fox's numbers on the season are 18.6 points, 3.8 boards and 6.2 assists per game, shooting 48.6% from the floor and 33.2% from downtown, with an average of 1.8 made treys.
• Stephon Castle averages 16.6 points, 5.3 boards and 7.4 assists.
• Keldon Johnson is averaging 13.2 points, 5.4 rebounds and 1.4 assists.
• Julian Champagnie is averaging 11.1 points, 5.8 rebounds and 1.5 assists.

Timberwolves Leaders

• Julius Randle is averaging 21.1 points, 6.7 boards and 5 assists for the Timberwolves.
• The Timberwolves are getting 28.8 points, 5 rebounds and 3.7 assists per game from Anthony Edwards.
• Per game, Rudy Gobert gives the Timberwolves 10.9 points, 11.5 boards and 1.7 assists, plus 0.8 steals and 1.6 blocks (sixth in league).
• The Timberwolves are getting 13.6 points, 6.2 boards and 2.2 assists per game from Naz Reid.
• The Timberwolves are getting 14.8 points, 4.2 rebounds and 2.7 assists per game from Jaden McDaniels.

For more NBA betting insights, check out FanDuel Research's NBA home page.

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