Guardians vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 7

Odds updated as of 2:11 a.m.

The MLB slate on Friday includes the Cleveland Guardians facing the Chicago White Sox.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Guardians vs White Sox Game Info

• Cleveland Guardians (57-59) vs. Chicago White Sox (59-55)
• Date: Friday, August 7, 2026
• Time: 7:40 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and CleGuardians.TV

Guardians vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-142) | CHW: (+120)
• Spread: CLE: -1.5 (+118) | CHW: +1.5 (-142)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Guardians vs White Sox Probable Starting Pitchers

Probable Pitchers: Parker Messick (Guardians) - 8-6, 2.57 ERA vs Noah Schultz (White Sox) - 3-8, 5.82 ERA

This contest's pitching matchup is set, as the Guardians will send Parker Messick (8-6) to the mound, while Noah Schultz (3-8) will answer the bell for the White Sox. When Messick starts, his team is 11-11-0 against the spread this season. Messick's team has a record of 7-9 this season when he starts and they are the favorite on the moneyline. The White Sox have gone 4-9-0 against the spread when Schultz starts. The White Sox have a 3-7 record in Schultz's 10 starts this season when they were the underdog on the moneyline.

Guardians vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (53.7%)

Guardians vs White Sox Moneyline

• The Guardians vs White Sox moneyline has Cleveland as a -142 favorite, while Chicago is a +120 underdog at home.

Guardians vs White Sox Spread

• The White Sox are hosting the Guardians, and are +1.5 on the runline. The White Sox are +118 to cover the spread, and the Guardians are -142.

Guardians vs White Sox Over/Under

• The Guardians-White Sox contest on Aug. 7 has been given an over/under of 8.5 runs. The over is set at -105 and the under at -115.

Bet on Cleveland Guardians vs. Chicago White Sox on FanDuel today!

Guardians vs White Sox Betting Trends

• The Guardians have been favorites in 61 games this season and have come away with the win 29 times (47.5%) in those contests.
• Cleveland has a record of 10-8 when favored by -142 or more this year.
• The Guardians and their opponents have gone over in 53 of their 110 games with a total set by sportsbooks this season.
• The Guardians have posted a record of 53-57-0 against the spread this season.
• The White Sox have been the underdog on the moneyline 85 total times this season. They've gone 40-45 in those games.
• Chicago has gone 23-27 in games it has played as a moneyline underdog with odds of +120 or longer (46%).
• The White Sox have had an over/under set by oddsmakers 111 times, and have combined with opponents to go over the total in 61 of those games (61-49-1).
• The White Sox have covered 58.6% of their games this season, going 65-46-0 against the spread.

Guardians Player Leaders

• Chase DeLauter leads Cleveland with 102 hits, batting .279 this season with 34 extra-base hits. He has an on-base percentage of .355 and a slugging percentage of .440.
• Among all qualifying hitters in the majors, his batting average ranks 34th, his on-base percentage ranks 38th, and he is 64th in slugging.
• Jose Ramirez is hitting .234 with 18 doubles, 10 home runs and 47 walks, while slugging .388 with an on-base percentage of .333.
• He ranks 116th in batting average, 74th in on-base percentage and 112th in slugging among qualified batters.
• Ramirez has picked up at least one hit in two games in a row. In his last five games he is batting .211 with four walks.
• Brayan Rocchio is batting .257 with a .379 slugging percentage and 50 RBI this year.
• Steven Kwan has 94 hits this season and a team-best OBP of .362.
• Kwan takes a six-game hitting streak into this game. During his last 10 outings he is batting .359 with two doubles, five walks and three RBIs.

White Sox Player Leaders

• Miguel Vargas leads the White Sox with 99 hits. He's batting .236 and slugging .471 with an on-base percentage of .341.
• Including all qualified players, he is 114th in batting average, while his on-base percentage is 59th and he is 34th in slugging.
• Chase Meidroth is slugging .405 to lead his team. He has a batting average of .275 with an on-base percentage of .352.
• He ranks 41st in batting average, 43rd in on-base percentage and 95th in slugging percentage in the majors.
• Sam Antonacci has accumulated a team-best .366 on-base percentage.
• Munetaka Murakami is hitting .236 with 10 doubles, 24 home runs and 60 walks.

Guardians vs White Sox Head to Head

• 7/4/2026: 3-1 CHW (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/3/2026: 4-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/2/2026: 6-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/24/2026: 4-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/23/2026: 2-1 CHW (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/22/2026: 6-5 CHW (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/14/2025: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 9/13/2025: 3-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 9/12/2025: 4-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 8/10/2025: 6-4 CHW (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)

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