Royals vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for May 4

Odds updated as of 7:11 p.m.

Monday's slate in the MLB includes a matchup between the Kansas City Royals and the Cleveland Guardians.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Royals vs Guardians Game Info

• Kansas City Royals (15-19) vs. Cleveland Guardians (18-17)
• Date: Monday, May 4, 2026
• Time: 7:40 p.m. ET
• Venue: Kauffman Stadium -- Kansas City, Missouri
• Coverage: Royals.TV and CleGuardians.TV

Royals vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: KC: (-122) | CLE: (+104)
• Spread: KC: -1.5 (+168) | CLE: +1.5 (-205)
• Total: 9 -- Over: (-112) | Under: (-108)

Royals vs Guardians Probable Starting Pitchers

Probable Pitchers: Michael Wacha (Royals) - 2-2, 3.13 ERA vs Tanner Bibee (Guardians) - 0-4, 4.08 ERA

This contest's pitching matchup is set, as the Royals will send Michael Wacha (2-2) to the mound, while Tanner Bibee (0-4) will get the nod for the Guardians. Wacha's team is 2-4-0 against the spread this season in his starts. Wacha's team is 1-1 this season when he starts and they're favored on the moneyline. The Guardians have a 1-6-0 record against the spread in Bibee's starts. The Guardians are 1-2 in Bibee's three starts this season that they were the underdog on the moneyline.

Royals vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Royals win (54.5%)

Royals vs Guardians Moneyline

• Kansas City is a -122 favorite on the moneyline, while Cleveland is a +104 underdog on the road.

Royals vs Guardians Spread

• The Royals are favored by 1.5 runs at home versus the Guardians. The Royals are +168 to cover the spread, while the Guardians are -205.

Royals vs Guardians Over/Under

• Royals versus Guardians, on May 4, has an over/under of 9, with the over being -112 and the under -108.

Bet on Kansas City Royals vs. Cleveland Guardians on FanDuel today!

Royals vs Guardians Betting Trends

• The Royals have come away with eight wins in the 14 contests they have been listed as the favorites in this season.
• Kansas City has a record of 5-4 when favored by -122 or more this year.
• The Royals and their opponents have gone over in 13 of their 32 games with a total set by sportsbooks this season.
• The Royals have an against the spread mark of 15-17-0 in 32 games with a line this season.
• The Guardians have won 50% of the games this season they were the underdog on the moneyline (9-9).
• When it has played as a moneyline underdog with odds of +104 or longer, Cleveland has a record of 7-8 (46.7%).
• The Guardians have combined with opponents to go over the total 17 times this season for a 17-17-0 record against the over/under.
• The Guardians have collected an 18-16-0 record ATS this season (covering 52.9% of the time).

Royals Player Leaders

• Bobby Witt Jr. leads Kansas City OPS (.765) this season. He has a .281 batting average, an on-base percentage of .357, and a slugging percentage of .407.
• Among qualified hitters in MLB, he ranks 40th in batting average, 53rd in on-base percentage, and 91st in slugging.
• Witt will look for his fourth straight game with a hit in this matchup. In his last five games he is hitting .238 with three walks.
• Maikel Garcia has nine doubles, a triple, three home runs and 13 walks. He's batting .270 and slugging .429 with an on-base percentage of .333.
• His batting average is 52nd among qualified players, his on-base percentage 86th, and his slugging percentage 66th.
• Garcia takes a four-game streak with at least one hit into this one. During his last five outings he is hitting .273 with three doubles, a home run, a walk and three RBIs.
• Vinnie Pasquantino has collected 22 base hits, an OBP of .283 and a slugging percentage of .350 this season.
• Pasquantino has recorded a hit in three games in a row. During his last five outings he is hitting .353 with a double, a home run, a walk and two RBIs.
• Carter Jensen leads Kansas City in total hits (23) this season while batting .230 with eight extra-base hits.

Guardians Player Leaders

• Jose Ramirez has eight doubles, six home runs and 24 walks while batting .217. He's slugging .419 with an on-base percentage of .340.
• Including all qualified players in the majors, his batting average puts him 137th, his on-base percentage ranks 74th, and he is 74th in slugging.
• Chase DeLauter paces his team with 34 hits and a .392 on-base percentage, with a team-high .554 slugging percentage. He has a batting average of .304.
• He is 25th in batting average, 20th in on-base percentage and 12th in slugging percentage in the majors.
• Brayan Rocchio is batting .268 with four doubles, three home runs and 11 walks.
• Angel Martinez is batting .275 with six doubles, five home runs and three walks.

Royals vs Guardians Head to Head

• 4/8/2026: 10-2 CLE (Favorite: Royals, Spread: -1.5, Total: 7, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/7/2026: 2-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 6.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/6/2026: 4-2 KC (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 9/11/2025: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/10/2025: 4-3 KC (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/9/2025: 2-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/8/2025: 10-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/27/2025: 4-1 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/26/2025: 6-4 CLE (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 7/26/2025: 5-3 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)

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