Reds vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for May 1

Odds updated as of 12:12 p.m.

The St. Louis Cardinals will face the Cincinnati Reds in MLB action on Thursday.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Cardinals vs Reds Game Info

• St. Louis Cardinals (14-17) vs. Cincinnati Reds (16-15)
• Date: Thursday, May 1, 2025
• Time: 12:40 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: FDSOH and FDSMW

Cardinals vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-118) | CIN: (-100)
• Spread: STL: -1.5 (+138) | CIN: +1.5 (-166)
• Total: 9 -- Over: (-110) | Under: (-110)

Cardinals vs Reds Probable Starting Pitchers

Probable Pitchers: Matthew Liberatore (Cardinals) - 2-2, 3.19 ERA vs Andrew Abbott (Reds) - 2-0, 3.60 ERA

This contest's pitching matchup is set, as the Cardinals will send Matthew Liberatore (2-2) to the mound, while Andrew Abbott (2-0) will take the ball for the Reds. Liberatore and his team have a record of 1-4-0 against the spread when he starts. Liberatore's team has been victorious in 33.3% of the games he's started as the moneyline favorite with a record of 1-2. When Abbott starts, the Reds have gone 2-1-0 against the spread. The Reds were named the moneyline underdog for one Abbott start this season -- they won.

Cardinals vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (51.8%)

Cardinals vs Reds Moneyline

• Cincinnati is a -100 underdog on the moneyline, while St. Louis is a -118 favorite on the road.

Cardinals vs Reds Spread

• The Cardinals are at the Reds and are favored by 1.5 runs (+138 to cover) on the runline. Cincinnati is -166 to cover.

Cardinals vs Reds Over/Under

• A total of 9 runs has been set for the Cardinals-Reds contest on May 1, with the over available at -110 and the under at -110.

Bet on St. Louis Cardinals vs. Cincinnati Reds on FanDuel today!

Cardinals vs Reds Betting Trends

• The Cardinals have come away with four wins in the nine contests they have been listed as the favorites in this season.
• This season St. Louis has come away with a win three times in five chances when named as a favorite of at least -118 on the moneyline.
• The Cardinals and their opponents have gone over the total this season in 16 of their 31 opportunities.
• The Cardinals have posted a record of 14-17-0 against the spread this season.
• The Reds have gone 7-9 in games they were listed as the moneyline underdog (winning 43.8% of those games).
• Cincinnati has a 6-6 record (winning 50% of its games) when it has played as a moneyline underdog of -100 or longer.
• The Reds have played in 31 games with a set over/under, and have combined with their opponents to go over the total 14 times (14-16-1).
• The Reds have covered 54.8% of their games this season, going 17-14-0 against the spread.

Cardinals Player Leaders

• Lars Nootbaar leads St. Louis with an OBP of .400 this season while batting .263 with 25 walks and 21 runs scored. He has a slugging percentage of .439.
• Among the qualified hitters in MLB, his batting average ranks 66th, his on-base percentage ranks 15th, and he is 58th in slugging.
• Brendan Donovan leads St. Louis with 38 hits and a team-best slugging percentage of .491. He's batting .333 with an on-base percentage of .379.
• He is fifth in batting average, 25th in on-base percentage and 36th in slugging in MLB.
• Nolan Arenado has collected 26 base hits, an OBP of .336 and a slugging percentage of .411 this season.
• Victor Scott II has two home runs, 14 RBI and a batting average of .271 this season.
• Scott takes a two-game hitting streak into this game. In his last five games he is hitting .250 with a home run, two walks and four RBI.

Reds Player Leaders

• Elly De La Cruz has a .438 slugging percentage, which paces the Reds. He's batting .281 with an on-base percentage of .348.
• Including all qualified hitters in the big leagues, he is 39th in batting average, 55th in on-base percentage and 60th in slugging percentage.
• De La Cruz heads into this matchup on a 14-game hitting streak. In his last 10 outings he is hitting .368 with a double, a home run, four walks and three RBI.
• TJ Friedl is hitting .275 with six doubles, a triple, a home run and 10 walks. He's slugging .367 with an on-base percentage of .333.
• Including all qualified players, he is 47th in batting average, 68th in on-base percentage and 111th in slugging percentage.
• Gavin Lux has racked up 32 hits with a .416 on-base percentage, leading the Reds in both categories.
• Austin Hays is hitting .365 with three doubles, five home runs and six walks.

Cardinals vs Reds Head to Head

• 4/30/2025: 9-1 STL (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/30/2025: 6-0 STL (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 4/28/2025: 3-1 CIN (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 9/12/2024: 6-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 9/11/2024: 2-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/10/2024: 3-0 CIN (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/14/2024: 9-2 CIN (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/13/2024: 4-1 CIN (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/12/2024: 6-1 CIN (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/30/2024: 2-0 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)

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