Reds vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for April 29

Odds updated as of 12:12 p.m.

Wednesday's slate in the MLB includes a matchup between the Cincinnati Reds and the St. Louis Cardinals.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Reds vs Cardinals Game Info

• Cincinnati Reds (16-13) vs. St. Louis Cardinals (12-17)
• Date: Wednesday, April 30, 2025
• Time: 12:40 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: FDSOH and FDSMW

Reds vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-130) | STL: (+110)
• Spread: CIN: -1.5 (+158) | STL: +1.5 (-192)
• Total: 9.5 -- Over: (-100) | Under: (-122)

Reds vs Cardinals Probable Starting Pitchers

Probable Pitchers: Brady Singer (Reds) - 4-0, 3.62 ERA vs Miles Mikolas (Cardinals) - 0-2, 5.70 ERA

The probable starters are Brady Singer (4-0) for the Reds and Miles Mikolas (0-2) for the Cardinals. Singer's team is 4-1-0 against the spread in his starts this season. Singer's team is 2-1 this season when he starts and they are the moneyline favorite. The Cardinals are 1-4-0 ATS in Mikolas' five starts with a set spread. The Cardinals were the underdog on the moneyline for four Mikolas starts this season -- they lost all of the games.

Reds vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (58.6%)

Reds vs Cardinals Moneyline

• The moneyline numbers for Reds vs. Cardinals reveal Cincinnati as the favorite (-130) and St. Louis as the underdog (+110) on the road.

Reds vs Cardinals Spread

• The Reds are favored by 1.5 runs at home versus the Cardinals. The Reds are +158 to cover the spread, while the Cardinals are -192.

Reds vs Cardinals Over/Under

• The over/under for the Reds versus Cardinals contest on April 30 has been set at 9.5, with -100 odds on the over and -122 odds on the under.

Bet on Cincinnati Reds vs. St. Louis Cardinals on FanDuel today!

Reds vs Cardinals Betting Trends

• The Reds have been chosen as favorites in 13 games this year and have walked away with the win nine times (69.2%) in those games.
• This season Cincinnati has been victorious five times in seven chances when named as a favorite of at least -130 on the moneyline.
• Contests with the Reds have gone over the total set by sportsbooks in 13 of 29 chances this season.
• The Reds are 17-12-0 against the spread in their 29 games with a line set by sportsbooks this season.
• The Cardinals have won 40% of the games this season they were the underdog on the moneyline (8-12).
• St. Louis is 3-8 (winning just 27.3% of its games) when playing as a moneyline underdog of +110 or longer.
• The Cardinals have played in 29 games with a set over/under, and have combined with their opponents to go over the total 15 times (15-12-2).
• The Cardinals have collected a 12-17-0 record ATS this season.

Reds Player Leaders

• Elly De La Cruz is hitting .270 with four doubles, five home runs and 12 walks. He has an on-base percentage of .336 and a slugging percentage of .435.
• Among all qualified hitters in the majors, he is 58th in batting average, 67th in on-base percentage, and 59th in slugging.
• De La Cruz has recorded at least one hit in 12 games in a row. In his last 10 games he is hitting .317 with a double, two home runs, five walks and six RBI.
• TJ Friedl leads Cincinnati in slugging percentage (.384) thanks to eight extra-base hits. He's batting .286 with an on-base percentage of .347.
• Among all qualifying hitters, he ranks 40th in batting average, 56th in on-base percentage and 102nd in slugging percentage.
• Austin Hays is batting .365 with a .712 slugging percentage and 13 RBI this year.
• Gavin Lux has 32 hits and an OBP of .438 to go with a slugging percentage of .473. All three of those stats lead Cincinnati hitters this season.
• Lux brings a 12-game hitting streak into this game. During his last 10 games he is hitting .472 with four doubles, a home run, six walks and seven RBI.

Cardinals Player Leaders

• Lars Nootbaar has a team-best .405 on-base percentage. He's batting .271 and slugging .430.
• Including all the qualified hitters in MLB, he is 54th in batting average, 13th in on-base percentage and 62nd in slugging percentage.
• Nootbaar hopes to build on a four-game hitting streak in this matchup. During his last five outings he is batting .389 with two doubles, five walks and three RBI.
• Brendan Donovan's 37 hits and .519 slugging percentage both lead his team. He has a batting average of .349 with an on-base percentage of .391.
• His batting average ranks fourth among all qualified players, his on-base percentage is 22nd, and he is 30th in slugging.
• Nolan Arenado is batting .255 with nine doubles, three home runs and 14 walks.
• Victor Scott II has five doubles, a triple, a home run and nine walks while hitting .258.

Reds vs Cardinals Head to Head

• 4/28/2025: 3-1 CIN (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 9/12/2024: 6-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 9/11/2024: 2-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/10/2024: 3-0 CIN (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/14/2024: 9-2 CIN (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/13/2024: 4-1 CIN (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/12/2024: 6-1 CIN (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/30/2024: 2-0 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/29/2024: 9-4 CIN (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 6/28/2024: 1-0 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)

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