Reds vs Blue Jays Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 2

Odds updated as of 6:12 a.m.

The Cincinnati Reds will take on the Toronto Blue Jays in MLB action on Tuesday.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Reds vs Blue Jays Game Info

• Cincinnati Reds (70-68) vs. Toronto Blue Jays (79-59)
• Date: Tuesday, September 2, 2025
• Time: 6:40 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: FDSOH and SNET

Reds vs Blue Jays Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-112) | TOR: (-104)
• Spread: CIN: +1.5 (-184) | TOR: -1.5 (+152)
• Total: 8.5 -- Over: (-112) | Under: (-108)

Reds vs Blue Jays Probable Starting Pitchers

Probable Pitchers: Nick Lodolo (Reds) - 8-7, 3.22 ERA vs José Berrios (Blue Jays) - 9-5, 3.95 ERA

The Reds will call on Nick Lodolo (8-7) against the Blue Jays and Jose Berrios (9-5). When Lodolo starts, his team is 12-10-0 against the spread this season. When Lodolo starts a game and his team is the favorite on the moneyline, they have a record of 6-4. The Blue Jays are 16-11-0 against the spread when Berrios starts. The Blue Jays have been the moneyline underdog in 12 of Berrios' starts this season, and they went 9-3 in those games.

Reds vs Blue Jays Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (56.3%)

Reds vs Blue Jays Moneyline

• Cincinnati is the favorite, -112 on the moneyline, while Toronto is a -104 underdog on the road.

Reds vs Blue Jays Spread

• The Blue Jays are 1.5-run favorites against the spread for this matchup with the Reds. The Blue Jays are +152 to cover, while the Reds are -184 to cover as a 1.5-run underdog on the runline.

Reds vs Blue Jays Over/Under

• Reds versus Blue Jays on Sept. 2 has an over/under of 8.5 runs, with the odds on the over -112 and the under set at -108.

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Reds vs Blue Jays Betting Trends

• The Reds have been favorites in 56 games this season and have come away with the win 30 times (53.6%) in those contests.
• This season Cincinnati has come away with a win 27 times in 52 chances when named as a favorite of at least -112 on the moneyline.
• The Reds and their opponents have hit the over in 52 of their 131 games with a total set by oddsmakers this season.
• The Reds have posted a record of 68-63-0 against the spread this season.
• The Blue Jays have gone 40-30 in games they were listed as the moneyline underdog (winning 57.1% of those games).
• When it has played as a moneyline underdog with odds of -104 or longer, Toronto has gone 34-27 (55.7%).
• The Blue Jays have combined with opponents to hit the over on the total 77 times this season for a 77-54-6 record against the over/under.
• The Blue Jays have collected an 80-57-0 record against the spread this season (covering 58.4% of the time).

Reds Player Leaders

• Elly De La Cruz has 147 hits to go with a slugging percentage of .455, both of which lead Cincinnati hitters this season. He has a .272 batting average and an on-base percentage of .341.
• He is 41st in batting average, 54th in on-base percentage, and 58th in slugging among qualified hitters in MLB.
• De La Cruz hopes to build on a six-game hitting streak in this matchup. During his last 10 outings he is batting .261 with three doubles, three triples and an RBI.
• TJ Friedl leads Cincinnati in OBP (.368) this season, fueled by 131 hits. He's batting .267 while slugging .376.
• Among all qualified, he is 52nd in batting average, 16th in on-base percentage and 134th in slugging percentage.
• Friedl takes a two-game streak with at least one hit into this matchup. During his last five outings he is batting .350 with a double, six walks and three RBIs.
• Spencer Steer has collected 107 base hits, an OBP of .304 and a slugging percentage of .398 this season.
• Austin Hays has been key for Cincinnati with 83 hits, an OBP of .316 plus a slugging percentage of .450.

Blue Jays Player Leaders

• Vladimir Guerrero Jr. has 30 doubles, 21 home runs and 73 walks while batting .287. He's slugging .476 with an on-base percentage of .383.
• Including all the qualified players in the majors, his batting average is 17th, his on-base percentage ranks eighth, and he is 36th in slugging.
• Bo Bichette leads his team with a .478 slugging percentage. He has a batting average of .310 with an on-base percentage of .354.
• Including all qualifying hitters, his batting average puts him third, his on-base percentage ranks 35th, and he is 34th in slugging.
• George Springer has totaled 121 hits with a .391 on-base percentage, leading the Blue Jays in both statistics.
• Ernie Clement is batting .273 with 25 doubles, two triples, nine home runs and 22 walks.

Reds vs Blue Jays Head to Head

• 9/1/2025: 5-4 CIN (Favorite: Reds, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/21/2024: 11-7 CIN (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/20/2024: 10-3 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/19/2024: 6-3 CIN (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/20/2023: 10-3 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 9.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/19/2023: 4-3 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 9.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/18/2023: 1-0 CIN (Favorite: Blue Jays, Spread: -1.5, Total: 10, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 5/22/2022: 3-2 CIN (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 5/21/2022: 3-1 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 5/20/2022: 2-1 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8, Favorite Moneyline: -190, Underdog Moneyline: +160)

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