Red Sox vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for April 19

Odds updated as of 4:20 p.m.

The Saturday slate in MLB includes a matchup between the Boston Red Sox and the Chicago White Sox.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Red Sox vs White Sox Game Info

• Boston Red Sox (11-10) vs. Chicago White Sox (4-15)
• Date: Saturday, April 19, 2025
• Time: 4:10 p.m. ET
• Venue: Fenway Park -- Boston, Massachusetts
• Coverage: NESN and CHSN

Red Sox vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-350) | CHW: (+280)
• Spread: BOS: -1.5 (-164) | CHW: +1.5 (+136)
• Total: 9 -- Over: (-120) | Under: (-102)

Red Sox vs White Sox Probable Starting Pitchers

Probable Pitchers: Garrett Nolan Crochet (Red Sox) - 2-1, 1.38 ERA vs Shane Smith (White Sox) - 0-1, 2.04 ERA

The Red Sox will look to Garrett Nolan Crochet (2-1) against the White Sox and Shane Smith (0-1). Crochet and his team have a record of 3-1-0 against the spread when he starts. Crochet's team has been victorious in 75% of the games he's started as the moneyline favorite with a record of 3-1. The White Sox have a 1-2-0 ATS record in Smith's three starts that had a set spread. The White Sox were the moneyline underdog for three Smith starts this season -- they lost each time.

Red Sox vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (71.3%)

Red Sox vs White Sox Moneyline

• Looking at the moneyline for White Sox-Red Sox, Chicago is the underdog at +280, and Boston is -350 playing at home.

Red Sox vs White Sox Spread

• The Red Sox are hosting the White Sox and are favored by 1.5 runs on the spread. The Red Sox are -164 to cover the runline, with the White Sox being +136.

Red Sox vs White Sox Over/Under

• The over/under for the Red Sox versus White Sox contest on April 19 has been set at 9, with -120 odds on the over and -102 odds on the under.

Bet on Boston Red Sox vs. Chicago White Sox on FanDuel today!

Red Sox vs White Sox Betting Trends

• The Red Sox have come away with eight wins in the 14 contests they have been listed as the favorites in this season.
• These are the best odds of a victory sportsbooks have given Boston this season, with a -350 moneyline set for this game.
• The Red Sox and their opponents have gone over the total this season in eight of their 21 opportunities.
• The Red Sox have an against the spread mark of 11-10-0 in 21 games with a line this season.
• The White Sox have compiled a 4-15 record in games they were the underdog on the moneyline (winning 21.1% of those games).
• Chicago has not yet played as a moneyline underdog of +280 or longer.
• The White Sox have combined with opponents to go over the total eight times this season for an 8-9-2 record against the over/under.
• The White Sox have put together a 9-10-0 record against the spread this season.

Red Sox Player Leaders

• Alexander David Bregman leads Boston with 25 hits, batting .309 this season with 11 extra-base hits. He has an on-base percentage of .367 and a slugging percentage of .543.
• He ranks 29th in batting average, 48th in on-base percentage, and 20th in slugging among qualifying hitters in baseball.
• Wilyer Abreu has 19 hits this season and a team-best OBP of .427. He's batting .306 and slugging .532.
• Among all qualifying players, he ranks 31st in batting average, eighth in on-base percentage and 24th in slugging percentage.
• Trevor Story leads Boston in slugging percentage (.531) powered by seven extra-base hits.
• Kristian Campbell has been key for Boston with 19 hits, an OBP of .385 plus a slugging percentage of .485.

White Sox Player Leaders

• Andrew Sebastian Benintendi has three home runs and three walks while batting .278. He's slugging .528 with an on-base percentage of .333.
• Lenyn Sosa's 17 hits, .313 OBP and .377 slugging percentage are all team-highs. He has a batting average of .279.
• Including all qualified hitters, he is 55th in batting average, 98th in on-base percentage and 98th in slugging percentage.
• Brooks Baldwin is batting .245 with a double, two home runs and a walk.
• Luis Robert has a double, a home run and eight walks while hitting .136.

Red Sox vs White Sox Head to Head

• 4/18/2025: 10-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 4/13/2025: 3-1 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 4/12/2025: 3-2 CHW (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 4/11/2025: 11-1 CHW (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 9/8/2024: 7-2 CHW (Favorite: Red Sox, Spread: -1.5, Total: 10, Favorite Moneyline: -275, Underdog Moneyline: +225)
• 9/7/2024: 7-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 9/6/2024: 3-1 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -290, Underdog Moneyline: +235)
• 6/9/2024: 6-4 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 6/8/2024: 6-1 CHW (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -240, Underdog Moneyline: +194)
• 6/7/2024: 7-2 CHW (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)

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