Red Sox vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 26

Odds updated as of 6:19 p.m.

In MLB action on Tuesday, the Boston Red Sox take on the Baltimore Orioles.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Red Sox vs Orioles Game Info

• Boston Red Sox (72-60) vs. Baltimore Orioles (60-71)
• Date: Tuesday, August 26, 2025
• Time: 6:35 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: MASN and NESN

Red Sox vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-118) | BAL: (-100)
• Spread: BOS: -1.5 (+138) | BAL: +1.5 (-166)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Red Sox vs Orioles Probable Starting Pitchers

Probable Pitchers: Lucas Giolito (Red Sox) - 8-2, 3.72 ERA vs Kyle Bradish (Orioles) - 0-0, 0.00 ERA

The Red Sox will call on Lucas Giolito (8-2) versus the Orioles and Kyle Bradish. Giolito and his team are 14-6-0 ATS this season when he starts. Giolito's team has won 77.8% of his starts when they are favored on the moneyline (7-2). Last season when Bradish pitched his team went 4-3-0 against the spread. Bradish did not pitch as a moneyline underdog a season ago.

Red Sox vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (51.6%)

Red Sox vs Orioles Moneyline

• Looking at the moneyline for Orioles-Red Sox, Baltimore is the underdog at -100, and Boston is -118 playing on the road.

Red Sox vs Orioles Spread

• The Orioles are hosting the Red Sox, and are +1.5 on the runline. The Orioles are +138 to cover the spread, and the Red Sox are -166.

Red Sox vs Orioles Over/Under

• Red Sox versus Orioles on Aug. 26 has an over/under of 8.5 runs, with the odds on the over -110 and the under set at -110.

Bet on Boston Red Sox vs. Baltimore Orioles on FanDuel today!

Red Sox vs Orioles Betting Trends

• The Red Sox have won in 46, or 58.2%, of the 79 contests they have been named as odds-on favorites in this year.
• This season Boston has been victorious 38 times in 62 chances when named as a favorite of at least -118 on the moneyline.
• The Red Sox and their opponents have hit the over in 64 of their 131 games with a total set by oddsmakers this season.
• The Red Sox are 72-59-0 against the spread in their 131 games that had a posted line this season.
• The Orioles are 32-37 in games they were listed as the moneyline underdog (winning 46.4% of those games).
• When playing as a moneyline underdog with odds of -100 or longer, Baltimore has a 24-29 record (winning 45.3% of its games).
• The Orioles have played in 128 games with a set over/under, and have combined with their opponents to go over the total 56 times (56-68-4).
• The Orioles have put together a 60-68-0 record against the spread this season (covering 46.9% of the time).

Red Sox Player Leaders

• Jarren Duran leads Boston in OBP (.335), slugging percentage (.447) and total hits (132) this season. He has a .258 batting average.
• Among the qualifying hitters in baseball, his batting average ranks 80th, his on-base percentage ranks 67th, and he is 70th in slugging.
• Trevor Story has 22 doubles, 20 home runs and 28 walks. He's batting .258 and slugging .424 with an on-base percentage of .305.
• Among qualifying hitters, his batting average ranks him 80th, his on-base percentage 121st, and his slugging percentage 85th.
• Alex Bregman has collected 97 base hits, an OBP of .386 and a slugging percentage of .525 this season.
• Ceddanne Rafaela is batting .247 with a .291 OBP and 53 RBI for Boston this season.

Orioles Player Leaders

• Gunnar Henderson has 132 hits with a .354 on-base percentage and a .472 slugging percentage, all club-bests for the Orioles. He's batting .283.
• Including all qualified hitters, he ranks 27th in batting average, while his on-base percentage is 34th and he is 42nd in slugging.
• Henderson heads into this matchup on a seven-game hitting streak. In his last 10 games he is hitting .282 with a double, a triple, two home runs, six walks and eight RBIs.
• Jackson Holliday is hitting .244 with 17 doubles, two triples, 15 home runs and 37 walks. He's slugging .380 with an on-base percentage of .305.
• Including all qualifying hitters, he is 114th in batting average, 121st in on-base percentage and 130th in slugging percentage.
• Colton Cowser is hitting .225 with 11 doubles, 12 home runs and 16 walks.
• Ryan Mountcastle is hitting .256 with 14 doubles, four home runs and 11 walks.

Red Sox vs Orioles Head to Head

• 8/25/2025: 4-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/19/2025: 4-3 BAL (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 8/18/2025: 6-3 BAL (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/25/2025: 5-1 BAL (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/24/2025: 2-1 BAL (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 5/24/2025: 6-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/23/2025: 19-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/3/2025: 8-4 BOS (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/2/2025: 3-0 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 3/31/2025: 8-5 BAL (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -146, Underdog Moneyline: +124)

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