Red Sox vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for April 12

Odds updated as of 2:11 p.m.

The Boston Red Sox versus the St. Louis Cardinals is on the MLB schedule for Sunday.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Red Sox vs Cardinals Game Info

• Boston Red Sox (5-9) vs. St. Louis Cardinals (8-6)
• Date: Sunday, April 12, 2026
• Time: 2:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: Cardinals.TV and NESN

Red Sox vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-118) | STL: (+100)
• Spread: BOS: -1.5 (+146) | STL: +1.5 (-176)
• Total: 8.5 -- Over: (-124) | Under: (+102)

Red Sox vs Cardinals Probable Starting Pitchers

Probable Pitchers: Brayan Bello (Red Sox) - 0-1, 9.00 ERA vs Andre Pallante (Cardinals) - 1-0, 1.80 ERA

The probable pitchers are Brayan Bello (0-1) for the Red Sox and Andre Pallante (1-0) for the Cardinals. Bello has a record of 0-2-0 ATS in two starts with a spread this season. This will be Bello's first game as the moneyline favorite this season. Pallante has started two games with set spreads, and the Cardinals went 1-1-0. The Cardinals were named the moneyline underdog for one Pallante start this season -- they won.

Red Sox vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (50.3%)

Red Sox vs Cardinals Moneyline

• St. Louis is a +100 underdog on the moneyline, while Boston is a -118 favorite on the road.

Red Sox vs Cardinals Spread

• The Red Sox are favored by 1.5 runs on the road against the Cardinals. The Red Sox are +146 to cover the spread, while the Cardinals are -176.

Red Sox vs Cardinals Over/Under

• Red Sox versus Cardinals, on April 12, has an over/under of 8.5, with the over being -124 and the under +102.

Bet on Boston Red Sox vs. St. Louis Cardinals on FanDuel today!

Red Sox vs Cardinals Betting Trends

• The Red Sox have been favorites in 12 games this season and have come away with the win five times (41.7%) in those contests.
• This year Boston has won five of 12 games when listed as at least -118 on the moneyline.
• The Red Sox's games have gone over the total in seven of their 14 opportunities.
• The Red Sox are 4-10-0 against the spread in their 14 games that had a posted line this season.
• The Cardinals have gone 7-5 in games they were listed as the moneyline underdog (winning 58.3% of those games).
• When playing as a moneyline underdog with odds of +100 or longer, St. Louis has a record of 5-4 (55.6%).
• The Cardinals have combined with opponents to hit the over on the total seven times this season for a 7-6-1 record against the over/under.
• The Cardinals have gone 7-7-0 against the spread this season.

Red Sox Player Leaders

• Wilyer Abreu has 20 hits to go with a slugging percentage of .636, both of which are best among Boston hitters this season. He has a .364 batting average and an on-base percentage of .397.
• Among qualifying hitters in MLB, he ranks third in batting average, 21st in on-base percentage, and eighth in slugging.
• Willson Contreras leads Boston in OBP (.419) this season, fueled by 12 hits. He's batting .250 while slugging .417.
• He is 74th in batting average, 13th in on-base percentage and 74th in slugging among qualifying hitters.
• Ceddanne Rafaela is batting .325 with a .425 slugging percentage and five RBI this year.
• Rafaela has recorded at least one base hit in seven straight games. During his last 10 games he is batting .333 with a double, a home run, two walks and four RBIs.
• Jarren Duran has no home runs, but five RBI and a batting average of .190 this season.

Cardinals Player Leaders

• Jordan Walker has accumulated a team-high OBP (.386) and slugging percentage (.706), while leading the Cardinals in hits (16, while batting .314).
• Including all the qualifying hitters in MLB, he ranks 27th in batting average, 33rd in on-base percentage and fourth in slugging percentage.
• Walker hopes to build on a seven-game hitting streak in this matchup. In his last 10 games he is batting .289 with five home runs, three walks and 10 RBIs.
• Alec Burleson is hitting .240 with two doubles, a home run and 11 walks. He's slugging .340 with an on-base percentage of .371.
• Including all qualified hitters, his batting average places him 84th, his on-base percentage ranks 45th, and he is 110th in slugging.
• JJ Wetherholt is batting .231 with a double, a home run and 10 walks.
• Ivan Herrera has three doubles and 13 walks while hitting .184.

Red Sox vs Cardinals Head to Head

• 4/11/2026: 7-1 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 4/10/2026: 3-2 STL (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 4/6/2025: 18-7 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/6/2025: 5-4 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/4/2025: 13-9 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/19/2024: 11-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/18/2024: 7-2 STL (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 5/17/2024: 10-6 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/14/2023: 9-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 10, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/13/2023: 4-3 STL (Favorite: Red Sox, Spread: -1.5, Total: 10.5, Favorite Moneyline: -134, Underdog Moneyline: +116)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!