Rays vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for April 6

Odds updated as of 11:19 p.m.

MLB action on Monday includes the Tampa Bay Rays taking on the Chicago Cubs.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Rays vs Cubs Game Info

• Tampa Bay Rays (4-5) vs. Chicago Cubs (4-5)
• Date: Monday, April 6, 2026
• Time: 4:10 p.m. ET
• Venue: Tropicana Field -- St. Petersburg, Florida
• Coverage: Rays.TV and MARQ

Rays vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-110) | CHC: (-106)
• Spread: TB: +1.5 (-192) | CHC: -1.5 (+158)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Rays vs Cubs Probable Starting Pitchers

Probable Pitchers: Shane McClanahan (Rays) - 0-1, 3.86 ERA vs Jameson Taillon (Cubs) - 0-0, 0.00 ERA

The probable starters are Shane McClanahan (0-1) for the Rays and Jameson Taillon for the Cubs. McClanahan and his team failed to cover the spread in his only opportunity this season as a starter. McClanahan has yet to start a game this season when his team was the moneyline favorite. Taillon has started just one game with a set spread, which the Cubs failed to cover. The Cubs have always been the moneyline underdog when Taillon starts this season.

Rays vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (54.7%)

Rays vs Cubs Moneyline

• Looking at the moneyline for Cubs-Rays, Chicago is the underdog at -106, and Tampa Bay is -110 playing at home.

Rays vs Cubs Spread

• The Cubs are 1.5-run favorites against the spread for this matchup with the Rays. The Cubs are +158 to cover, while the Rays are -192 to cover as a 1.5-run underdog on the runline.

Rays vs Cubs Over/Under

• A total of 7.5 runs has been set for the Rays-Cubs game on April 6, with the over available at -115 and the under at -105.

Bet on Tampa Bay Rays vs. Chicago Cubs on FanDuel today!

Rays vs Cubs Betting Trends

• The Rays have been favorites in four games this season and have come away with the win two times (50%) in those contests.
• This season Tampa Bay has been victorious two times in four chances when named as a favorite of at least -110 on the moneyline.
• The Rays and their opponents have gone over the total this season in seven of their nine opportunities.
• The Rays have an against the spread mark of 4-5-0 in nine games with a line this season.
• The Cubs are the moneyline underdog in their first game this season.
• Chicago has not played a game this season with moneyline odds of -106 or longer.
• The Cubs have had an over/under set by bookmakers nine times, and have combined with opponents to go over the total in four of those games (4-5-0).
• The Cubs are 3-6-0 ATS this season.

Rays Player Leaders

• Yandy Diaz leads Tampa Bay with 15 hits and an OBP of .488, plus a team-best slugging percentage of .649. He's batting .405.
• Among qualifying hitters, he ranks fifth in batting average, his on-base percentage ranks seventh, and he is 13th in slugging.
• Diaz will look for his fifth straight game with a hit in this matchup. During his last five outings he is batting .235 with a triple, a home run, three walks and four RBIs.
• Jonathan Aranda is batting .216 with two doubles, two home runs and six walks, while slugging .432 with an on-base percentage of .318.
• Among qualified hitters, he ranks 118th in batting average, 99th in on-base percentage and 70th in slugging percentage.
• Chandler Simpson has collected 13 base hits, an OBP of .432 and a slugging percentage of .441 this season.
• Simpson brings a two-game hitting streak into this matchup. During his last five outings he is hitting .368 with a triple and two walks.
• Nick Fortes has been key for Tampa Bay with nine hits, an OBP of .407 plus a slugging percentage of .560.
• Fortes brings a five-game hitting streak into this matchup. During his last five outings he is batting .294 with two doubles, a home run and four RBIs.

Cubs Player Leaders

• Nico Hoerner has a .436 on-base percentage and a .448 slugging percentage, both team-best numbers for the Cubs. He's batting .276.
• Including all the qualified hitters in the big leagues, he ranks 56th in batting average, 15th in on-base percentage and 65th in slugging percentage.
• Ian Happ's seven hits lead his team. He has a batting average of .189 while slugging .541 with an on-base percentage of .268.
• His batting average ranks 144th among all qualified players, his on-base percentage ranks 150th, and he is 35th in slugging.
• Alex Bregman is hitting .167 with two home runs and five walks.
• Miguel Amaya is hitting .417 with a double, a home run and two walks.

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