Pistons vs. Cavaliers Eastern Semifinals Prediction, Odds, Picks, Best Bets for May 17

Pistons vs. Cavaliers Game Info

• Date: Sunday, May 17, 2026
• Time: 8 p.m. ET
• Venue: Little Caesars Arena -- Detroit, Michigan
• Coverage: Amazon Prime Video

The Detroit Pistons and the Cleveland Cavaliers square off in a decisive Game 7 of the second round of the NBA Playoffs. The Pistons are favored by 4.5 points in the contest, which airs on Amazon Prime Video at 8 p.m. ET. The point total for the matchup is set at 205.5.

Pistons vs. Cavaliers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Pistons vs. Cavaliers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Pistons win (68.1%)

Pistons vs. Cavaliers Betting Trends

• The Pistons have compiled a 44-35-2 record against the spread this season.
• Against the spread, the Cavaliers are 33-47-2 this season.
• This season, Pistons games have hit the over 40 times.
• Cavaliers games this year have hit the over on 41 of 82 set point totals (50%).
• When playing at home, Detroit owns a worse record against the spread (21-19-1) compared to its ATS record in road games (23-16-1).
• The Pistons have exceeded the over/under in the same percentage of home games as road games (48.8%).
• This season, Cleveland is 17-23-1 at home against the spread (.415 winning percentage). Away, it is 16-24-1 ATS (.390).
• In 2025-26 a lower percentage of the Cavaliers' games have finished above the over/under at home (41.5%, 17 of 41) compared to on the road (58.5%, 24 of 41).

Pistons Leaders

• Cade Cunningham's numbers on the season are 23.9 points, 5.5 boards and 9.9 assists per contest, shooting 46.1% from the floor and 34.2% from downtown, with an average of 2 made 3-pointers.
• Jalen Duren averages 19.5 points, 10.5 boards and 2 assists.
• Ausar Thompson is averaging 9.9 points, 5.7 rebounds and 3.1 assists. At the other end, he averages 2 steals (first in NBA) and 0.9 blocked shots.
• Tobias Harris is averaging 13.3 points, 5.1 boards and 2.5 assists.
• Duncan Robinson averages 12.2 points, 2.7 rebounds and 2.1 assists, shooting 45.6% from the floor and 41% from downtown, with 2.9 made treys per game.

Cavaliers Leaders

• Per game, Donovan Mitchell gives the Cavaliers 27.9 points, 4.5 boards and 5.7 assists. He also averages 1.5 steals (ninth in league) and 0.3 blocks.
• Per game, James Harden provides the Cavaliers 23.6 points, 4.8 rebounds and 8 assists. He also averages 1.1 steals and 0.4 blocks.
• Evan Mobley averages 18.2 points, 9 rebounds and 3.6 assists. He is making 54.6% of his shots from the field and 29.7% from 3-point range, with 1 treys per game.
• Jarrett Allen's numbers on the season are 15.4 points, 8.5 rebounds and 1.8 assists per game. He is draining 63.8% of his shots from the floor (fifth in NBA).
• The Cavaliers are receiving 13.2 points, 5.1 boards and 2.2 assists per game from Jaylon Tyson.

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