Pirates vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for June 26

Odds updated as of 2:12 a.m.

The Pittsburgh Pirates will take on the Cincinnati Reds in MLB action on Friday.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Pirates vs Reds Game Info

• Pittsburgh Pirates (41-40) vs. Cincinnati Reds (37-42)
• Date: Friday, June 26, 2026
• Time: 6:40 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and Reds.TV

Pirates vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-220) | CIN: (+184)
• Spread: PIT: -1.5 (+104) | CIN: +1.5 (-125)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Pirates vs Reds Probable Starting Pitchers

Probable Pitchers: Paul Skenes (Pirates) - 6-7, 2.86 ERA vs Andrew Abbott (Reds) - 5-4, 3.83 ERA

The Pirates will call on Paul Skenes (6-7) against the Reds and Andrew Abbott (5-4). Skenes' team is 5-11-0 against the spread in his starts this season. Skenes' team has been victorious in 40% of the games he's started as the moneyline favorite with a record of 6-9. The Reds have gone 9-7-0 ATS in Abbott's 16 starts with a set spread. The Reds have a 6-6 record in Abbott's 12 starts this season when they were the moneyline underdog.

Pirates vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (71.2%)

Pirates vs Reds Moneyline

• Cincinnati is a +184 underdog on the moneyline, while Pittsburgh is a -220 favorite at home.

Pirates vs Reds Spread

• The Reds are +1.5 on the run line against the Pirates. The Reds are -125 to cover, and the Pirates are +104.

Pirates vs Reds Over/Under

• Pirates versus Reds, on June 26, has an over/under of 7.5, with the over being -115 and the under -105.

Bet on Pittsburgh Pirates vs. Cincinnati Reds on FanDuel today!

Pirates vs Reds Betting Trends

• The Pirates have won in 26, or 56.5%, of the 46 contests they have been named as odds-on favorites in this year.
• Pittsburgh has a record of 2-2 when favored by -220 or more this year.
• The Pirates' games have gone over the total in 45 of their 80 opportunities.
• The Pirates are 40-40-0 against the spread in their 80 games with a line set by sportsbooks this season.
• The Reds have a 24-27 record in games they were the underdog on the moneyline (winning 47.1% of those games).
• Cincinnati has played as a moneyline underdog of +184 or longer in just one game this season, which it lost.
• The Reds have had an over/under set by oddsmakers 77 times, and have combined with opponents to go over the total in 45 of those games (45-31-1).
• The Reds have collected a 43-34-0 record ATS this season.

Pirates Player Leaders

• Bryan Reynolds leads Pittsburgh with an OBP of .405, plus a team-best slugging percentage of .484. He's batting .291 on the season.
• Among qualified hitters in baseball, his batting average ranks 19th, his on-base percentage ranks fifth, and he is 35th in slugging.
• Reynolds hopes to build on a 15-game hitting streak in this matchup. During his last 10 outings he is batting .472 with four doubles, four home runs, six walks and 11 RBIs.
• Brandon Lowe leads Pittsburgh with 73 hits. He is batting .249 this season and has 39 extra-base hits. He's also slugging .515 with an on-base percentage of .326.
• Among all qualified, he is 83rd in batting average, 90th in on-base percentage and 20th in slugging percentage.
• Lowe heads into this game looking to extend his nine-game hit streak. In his last 10 games he is hitting .273 with three doubles, two home runs, two walks and five RBIs.
• Ryan O'Hearn has 70 hits this season and has a slash line of .285/.341/.463.
• O'Hearn takes a three-game hitting streak into this matchup. In his last five games he is batting .286 with three doubles and four RBIs.
• Nick Gonzales leads Pittsburgh with a slugging percentage of .375, fueled by 15 extra-base hits.
• Gonzales takes a four-game hitting streak into this matchup. During his last five outings he is batting .350 with a home run and two RBIs.

Reds Player Leaders

• Sal Stewart has a team-best .448 slugging percentage. He's batting .249 with an on-base percentage of .341.
• Including all the qualifying hitters in the big leagues, his batting average is 83rd, his on-base percentage ranks 63rd, and he is 61st in slugging.
• Spencer Steer is hitting .240 with 13 doubles, 13 home runs and 29 walks. He's slugging .434 with an on-base percentage of .319.
• His batting average is 101st among all qualified players, his on-base percentage ranks 100th, and he is 74th in slugging.
• Elly De La Cruz has racked up 66 hits with a .346 on-base percentage, leading the Reds in both categories.
• JJ Bleday is batting .243 with 11 doubles, a triple, 13 home runs and 29 walks.

Pirates vs Reds Head to Head

• 5/3/2026: 1-0 PIT (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/2/2026: 17-7 PIT (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/1/2026: 8-3 PIT (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 3/31/2026: 8-3 PIT (Favorite: Pirates, Spread: -1.5, Total: 9, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 3/30/2026: 2-0 CIN (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/24/2025: 4-3 PIT (Favorite: Reds, Spread: -1.5, Total: 7, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 9/23/2025: 4-2 PIT (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 8/10/2025: 14-8 CIN (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/9/2025: 2-1 CIN (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 8/8/2025: 3-2 PIT (Favorite: Reds, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!