Pirates vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for April 16

Odds updated as of 12:11 p.m.

In MLB action on Thursday, the Pittsburgh Pirates take on the Washington Nationals.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding this game.

Pirates vs Nationals Game Info

• Pittsburgh Pirates (11-7) vs. Washington Nationals (8-10)
• Date: Thursday, April 16, 2026
• Time: 12:35 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and Nationals.TV

Pirates vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-158) | WSH: (+134)
• Spread: PIT: -1.5 (+134) | WSH: +1.5 (-162)
• Total: 8.5 -- Over: (-122) | Under: (+100)

Pirates vs Nationals Probable Starting Pitchers

Probable Pitchers: Braxton Ashcraft (Pirates) - 1-1, 2.12 ERA vs Foster Griffin (Nationals) - 2-0, 1.76 ERA

The probable starters are Braxton Ashcraft (1-1) for the Pirates and Foster Griffin (2-0) for the Nationals. Ashcraft and his team are 2-1-0 ATS this season when he starts. Ashcraft's team won his only start as a favorite this season. When Griffin starts, the Nationals are 2-1-0 against the spread. The Nationals have a 2-1 record in Griffin's three starts this season when they were the moneyline underdog.

Pirates vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (67.7%)

Pirates vs Nationals Moneyline

• The moneyline numbers for Pirates vs. Nationals reveal Pittsburgh as the favorite (-158) and Washington as the underdog (+134) on the road.

Pirates vs Nationals Spread

• The Pirates are hosting the Nationals and are favored by 1.5 runs on the spread. The Pirates are +134 to cover the runline, with the Nationals being -162.

Pirates vs Nationals Over/Under

• The over/under for Pirates-Nationals on April 16 is 8.5. The over is -122, and the under is +100.

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Pirates vs Nationals Betting Trends

• The Pirates have come away with seven wins in the nine contests they have been listed as the favorites in this season.
• Pittsburgh has a record of 2-1 when favored by -158 or more this year.
• The Pirates and their opponents have hit the over in 10 of their 18 games with a total set by oddsmakers this season.
• In 18 games with a line this season, the Pirates have a mark of 12-6-0 against the spread.
• The Nationals have put together an 8-9 record in games they were listed as the moneyline underdog (winning 47.1% of those games).
• Washington is 7-8 (winning 46.7% of its games) when it has played as a moneyline underdog of +134 or longer.
• The Nationals have combined with opponents to go over the total 12 times this season for a 12-6-0 record against the over/under.
• The Nationals have an 11-7-0 record against the spread this season.

Pirates Player Leaders

• Brandon Lowe leads Pittsburgh with 15 hits, batting .250 this season with nine extra-base hits. He has an on-base percentage of .375 and a slugging percentage of .633.
• Among all qualifying hitters, he is 80th in batting average, his on-base percentage ranks 37th, and he is eighth in slugging.
• Oneil Cruz leads Pittsburgh in slugging percentage (.563) thanks to eight extra-base hits. He's batting .310 with an on-base percentage of .380.
• He ranks 23rd in batting average, 32nd in on-base percentage and 20th in slugging among qualifying hitters.
• Ryan O'Hearn leads Pittsburgh in OBP (.413) this season, fueled by 21 hits.
• Bryan Reynolds has been key for Pittsburgh with 19 hits, an OBP of .400 plus a slugging percentage of .470.

Nationals Player Leaders

• C.J. Abrams has put up a team-best OBP (.458) and slugging percentage (.717), and leads the Nationals in hits (22, while batting .367).
• He is fourth in batting average, fourth in on-base percentage and third in slugging percentage among all qualified batters in the big leagues.
• Abrams takes a six-game hitting streak into this matchup. In his last 10 outings he is hitting .438 with three doubles, three home runs, four walks and seven RBIs.
• James Wood is hitting .250 with six doubles, five home runs and 14 walks. He's slugging .542 with an on-base percentage of .379.
• His batting average is 80th among all qualified players, his on-base percentage ranks 35th, and he is 26th in slugging.
• Daylen Lile has four doubles and four walks while batting .269.
• Luis Garcia is batting .246 with three doubles, a triple, a home run and three walks.

Pirates vs Nationals Head to Head

• 4/15/2026: 2-0 PIT (Favorite: Pirates, Spread: -1.5, Total: 9.5, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 4/14/2026: 5-4 WSH (Favorite: Pirates, Spread: -1.5, Total: 9.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/13/2026: 16-5 PIT (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 9/14/2025: 4-3 WSH (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/13/2025: 5-1 PIT (Favorite: Pirates, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/12/2025: 6-5 WSH (Favorite: Nationals, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 4/17/2025: 1-0 PIT (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 4/16/2025: 6-1 PIT (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/15/2025: 3-0 WSH (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 4/14/2025: 10-3 PIT (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -198, Underdog Moneyline: +166)

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