Pirates vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for April 16

Odds updated as of 8:12 p.m.

In MLB action on Thursday, the Pittsburgh Pirates play the Washington Nationals.

We've got you covered, in terms of the vital information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Pirates vs Nationals Game Info

• Pittsburgh Pirates (10-7) vs. Washington Nationals (8-9)
• Date: Thursday, April 16, 2026
• Time: 12:35 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and Nationals.TV

Pirates vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-166) | WSH: (+140)
• Spread: PIT: -1.5 (+128) | WSH: +1.5 (-154)
• Total: 8.5 -- Over: (-122) | Under: (+100)

Pirates vs Nationals Probable Starting Pitchers

Probable Pitchers: Braxton Ashcraft (Pirates) - 1-1, 2.12 ERA vs Foster Griffin (Nationals) - 2-0, 1.76 ERA

The Pirates will give the ball to Braxton Ashcraft (1-1, 2.12 ERA), who is eyeing win No. 2 on the season, and the Nationals will turn to Foster Griffin (2-0, 1.76 ERA). Ashcraft and his team have a record of 2-1-0 against the spread when he starts. Ashcraft's team won his only start as a favorite this season. The Nationals have a 2-1-0 record against the spread in Griffin's starts. The Nationals are 2-1 in Griffin's three starts this season that they were the underdog on the moneyline.

Pirates vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (68.2%)

Pirates vs Nationals Moneyline

• Looking at the moneyline for Nationals-Pirates, Washington is the underdog at +140, and Pittsburgh is -166 playing at home.

Pirates vs Nationals Spread

• The Pirates are 1.5-run home favorites on the runline against the Nationals. The Pirates are +128 to cover, and the Nationals are -154.

Pirates vs Nationals Over/Under

• The over/under for Pirates-Nationals on April 16 is 8.5. The over is -122, and the under is +100.

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Pirates vs Nationals Betting Trends

• The Pirates have been chosen as favorites in eight games this year and have walked away with the win six times (75%) in those games.
• Pittsburgh has been listed as a favorite of -166 or more on two occasions this season and split those games.
• The Pirates and their opponents have hit the over in 10 of their 17 games with a total set by oddsmakers this season.
• The Pirates have posted a record of 11-6-0 against the spread this season.
• The Nationals are 8-8 in games they were the underdog on the moneyline (winning 50% of those games).
• When it has played as a moneyline underdog with odds of +140 or longer, Washington has a record of 7-7 (50%).
• The Nationals have played in 17 games with a set over/under, and have combined with their opponents to go over the total 12 times (12-5-0).
• The Nationals are 11-6-0 ATS this season.

Pirates Player Leaders

• Brandon Lowe has 15 hits, which ranks first among Pittsburgh hitters this season, while batting .268 with nine extra-base hits. He has an on-base percentage of .397 and a slugging percentage of .679.
• He is 67th in batting average, 22nd in on-base percentage, and sixth in slugging among all qualified hitters in baseball.
• Lowe has picked up at least one hit in three straight games. During his last five outings he is batting .316 with four home runs, four walks and 11 RBIs.
• Oneil Cruz leads the Pirates with an OPS of .997. He has a slash line of .328/.400/.597 this season.
• He is 13th in batting average, 19th in on-base percentage and 10th in slugging among qualified batters.
• Ryan O'Hearn has 18 hits this season and has a slash line of .305/.394/.508.
• Bryan Reynolds is batting .292 with a .382 OBP and 12 RBI for Pittsburgh this season.
• Reynolds enters this game on a five-game hitting streak. In his last five games he is batting .400 with a triple, a home run, a walk and seven RBIs.

Nationals Player Leaders

• C.J. Abrams has an on-base percentage of .426, a slugging percentage of .695, and has 21 hits, all club-bests for the Nationals (while batting .356).
• Including all the qualifying players in the majors, his batting average places him fifth, his on-base percentage is 12th, and he is fifth in slugging.
• Abrams heads into this matchup on a five-game hitting streak. In his last five games he is batting .529 with two doubles, two home runs and five RBIs.
• James Wood is hitting .265 with six doubles, five home runs and 14 walks. He's slugging .574 with an on-base percentage of .398.
• Including all qualifying players, his batting average puts him 69th, his on-base percentage ranks 21st, and he is 15th in slugging.
• Daylen Lile has accumulated a slugging percentage of .338, a team-best for the Nationals.
• Jacob Young has four doubles, two home runs and two walks while hitting .265.

Pirates vs Nationals Head to Head

• 4/14/2026: 5-4 WSH (Favorite: Pirates, Spread: -1.5, Total: 9.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/13/2026: 16-5 PIT (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 9/14/2025: 4-3 WSH (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/13/2025: 5-1 PIT (Favorite: Pirates, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/12/2025: 6-5 WSH (Favorite: Nationals, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 4/17/2025: 1-0 PIT (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 4/16/2025: 6-1 PIT (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/15/2025: 3-0 WSH (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 4/14/2025: 10-3 PIT (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 9/8/2024: 7-3 PIT (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)

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