Pirates vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for July 25

Odds updated as of 6:12 p.m.

On Saturday in MLB, the Pittsburgh Pirates are playing the Chicago Cubs.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Pirates vs Cubs Game Info

• Pittsburgh Pirates (53-51) vs. Chicago Cubs (58-45)
• Date: Saturday, July 25, 2026
• Time: 6:40 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and MARQ

Pirates vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-120) | CHC: (+102)
• Spread: PIT: +1.5 (-205) | CHC: -1.5 (+168)
• Total: 8 -- Over: (-102) | Under: (-120)

Pirates vs Cubs Probable Starting Pitchers

Probable Pitchers: Paul Skenes (Pirates) - 9-8, 3.43 ERA vs Shota Imanaga (Cubs) - 6-8, 3.91 ERA

The probable starters are Paul Skenes (9-8) for the Pirates and Shota Imanaga (6-8) for the Cubs. Skenes and his team have a record of 8-13-0 against the spread when he starts. Skenes' team has won 44.4% of his starts when they are favored on the moneyline (8-10). The Cubs have a 6-13-0 ATS record in Imanaga's 19 starts with a set spread. The Cubs were the underdog on the moneyline for two Imanaga starts this season -- they split the games.

Pirates vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (57.9%)

Pirates vs Cubs Moneyline

• Pittsburgh is a -120 favorite on the moneyline, while Chicago is a +102 underdog on the road.

Pirates vs Cubs Spread

• The Cubs are 1.5-run favorites against the spread for this matchup with the Pirates. The Cubs are +168 to cover, while the Pirates are -205 to cover as a 1.5-run underdog on the runline.

Pirates vs Cubs Over/Under

• The over/under for Pirates-Cubs on July 25 is 8. The over is -102, and the under is -120.

Bet on Pittsburgh Pirates vs. Chicago Cubs on FanDuel today!

Pirates vs Cubs Betting Trends

• The Pirates have won in 31, or 58.5%, of the 53 contests they have been named as odds-on favorites in this year.
• Pittsburgh has a record of 23-22 when favored by -120 or more this year.
• The Pirates' games have gone over the total in 59 of their 102 opportunities.
• The Pirates are 53-49-0 against the spread in their 102 games with a line set by sportsbooks this season.
• The Cubs have been the underdog on the moneyline 29 total times this season. They've finished 16-13 in those games.
• Chicago has a record of 10-9 in games it has played as a moneyline underdog with odds of +102 or longer (52.6%).
• The Cubs have played in 99 games with a set over/under, and have combined with their opponents to go over the total 53 times (53-46-0).
• The Cubs have put together a 44-55-0 record against the spread this season (covering 44.4% of the time).

Pirates Player Leaders

• Bryan Reynolds leads Pittsburgh with an OBP of .386 this season while batting .272 with 64 walks and 71 runs scored. He has a slugging percentage of .456.
• Among qualified hitters in MLB, his batting average ranks 45th, his on-base percentage ranks eighth, and he is 49th in slugging.
• Brandon Lowe leads Pittsburgh with 91 hits. He is batting .241 this season and has 43 extra-base hits. He's also slugging .468 with an on-base percentage of .311.
• His batting average is 100th among qualified players, his on-base percentage 107th, and his slugging percentage 40th.
• Nick Gonzales leads Pittsburgh in slugging percentage (.412) powered by 24 extra-base hits.
• Gonzales enters this game with eight games in a row with at least one hit. During his last 10 outings he is batting .326 with four doubles, two home runs, a walk and six RBIs.
• Ryan O'Hearn is batting .277 with a .340 OBP and 64 RBI for Pittsburgh this season.

Cubs Player Leaders

• Pete Crow-Armstrong has put up an on-base percentage of .385, a slugging percentage of .527, and has 109 hits, all club-highs for the Cubs (while batting .285).
• He is 22nd in batting average, ninth in on-base percentage and 14th in slugging percentage among all qualifying hitters in the big leagues.
• Nico Hoerner is hitting .244 with 23 doubles, a triple, four home runs and 36 walks. He's slugging .336 with an on-base percentage of .310.
• He is 93rd in batting average, 109th in on-base percentage and 141st in slugging percentage in the majors.
• Dansby Swanson has 12 doubles, three triples, 16 home runs and 39 walks while hitting .213.
• Alex Bregman is hitting .237 with 15 doubles, a triple, 10 home runs and 52 walks.

Pirates vs Cubs Head to Head

• 7/24/2026: 3-2 CHC (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/28/2026: 7-2 CHC (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 5/27/2026: 10-4 CHC (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/26/2026: 12-1 PIT (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 5/25/2026: 2-1 PIT (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 4/12/2026: 7-6 CHC (Favorite: Cubs, Spread: -1.5, Total: 12.5, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 4/11/2026: 4-3 PIT (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 4/10/2026: 2-0 PIT (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 9/17/2025: 8-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 9/16/2025: 4-1 CHC (Favorite: Pirates, Spread: -1.5, Total: 6.5, Favorite Moneyline: -132, Underdog Moneyline: +112)

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