Pirates vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for June 3

Odds updated as of 4:12 a.m.

The MLB schedule on Wednesday includes the Pittsburgh Pirates taking on the Houston Astros.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Pirates vs Astros Game Info

• Pittsburgh Pirates (33-28) vs. Houston Astros (27-35)
• Date: Wednesday, June 3, 2026
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and SportsNet PT

Pirates vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-164) | HOU: (+138)
• Spread: PIT: -1.5 (+104) | HOU: +1.5 (-125)
• Total: 7.5 -- Over: (-122) | Under: (+100)

Pirates vs Astros Probable Starting Pitchers

Probable Pitchers: Paul Skenes (Pirates) - 6-5, 2.89 ERA vs Spencer Arrighetti (Astros) - 7-1, 1.34 ERA

The Pirates will give the ball to Paul Skenes (6-5, 2.89 ERA), who is eyeing win No. 7 on the season, and the Astros will turn to Spencer Arrighetti (7-1, 1.34 ERA). When Skenes starts, his team is 5-7-0 against the spread this season. Skenes' team has been victorious in 54.5% of the games he's started as the moneyline favorite with a record of 6-5. The Astros are 7-1-0 ATS in Arrighetti's eight starts that had a set spread. The Astros are 6-1 in Arrighetti's seven starts this season that they were the underdog on the moneyline.

Pirates vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (59.6%)

Pirates vs Astros Moneyline

• The Pirates vs Astros moneyline has Pittsburgh as a -164 favorite, while Houston is a +138 underdog at home.

Pirates vs Astros Spread

• The Astros are +1.5 on the run line against the Pirates. The Astros are -125 to cover, and the Pirates are +104.

Pirates vs Astros Over/Under

• Pirates versus Astros, on June 3, has an over/under of 7.5, with the over being -122 and the under +100.

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Pirates vs Astros Betting Trends

• The Pirates have won in 22, or 61.1%, of the 36 contests they have been named as odds-on favorites in this year.
• Pittsburgh has a record of 5-4 in contests when bookmakers favor them by -164 or more on the moneyline.
• The Pirates and their opponents have hit the over in 33 of their 60 games with a total set by oddsmakers this season.
• In 60 games with a line this season, the Pirates have a mark of 30-30-0 against the spread.
• The Astros have put together a 21-23 record in games they were listed as the moneyline underdog (winning 47.7% of those games).
• When it has played as a moneyline underdog with odds of +138 or longer, Houston has a record of 3-6 (33.3%).
• The Astros have had an over/under set by oddsmakers 62 times, and have combined with opponents to go over the total in 34 of those games (34-26-2).
• The Astros have a 28-34-0 record ATS this season (covering 45.2% of the time).

Pirates Player Leaders

• Bryan Reynolds leads Pittsburgh in OBP (.403) this season, fueled by 58 hits. He has a .272 batting average and a slugging percentage of .432.
• Among qualifying hitters in MLB, he is 51st in batting average, sixth in on-base percentage, and 67th in slugging.
• Brandon Lowe has 55 hits, which is tops among Pittsburgh batters this season. He's batting .258 with 28 extra-base hits. He's also slugging .535 with an on-base percentage of .343.
• He is 66th in batting average, 64th in on-base percentage and ninth in slugging among qualifying hitters.
• Lowe takes a three-game streak with at least one hit into this one. During his last five outings he is batting .150 with a home run, a walk and four RBIs.
• Oneil Cruz has collected 62 base hits, an OBP of .331 and a slugging percentage of .475 this season.
• Spencer Horwitz has been key for Pittsburgh with 50 hits, an OBP of .385 plus a slugging percentage of .458.

Astros Player Leaders

• Yordan Alvarez has totaled 67 hits with a .419 on-base percentage and a .645 slugging percentage, all club-highs for the Astros. He's batting .305.
• He is 12th in batting average, second in on-base percentage and second in slugging percentage among all qualifying batters in the big leagues.
• Christian Walker is batting .248 with 10 doubles, 16 home runs and 21 walks. He's slugging .504 with an on-base percentage of .321.
• He is currently 86th in batting average, 98th in on-base percentage and 26th in slugging percentage among all qualifying hitters.
• Isaac Paredes is batting .233 with 10 doubles, six home runs and 21 walks.
• Cam Smith is batting .216 with eight doubles, six home runs and 24 walks.

Pirates vs Astros Head to Head

• 6/2/2026: 10-6 PIT (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/4/2025: 3-0 PIT (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/3/2025: 3-0 HOU (Favorite: Pirates, Spread: -1.5, Total: 7, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 7/31/2024: 5-4 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 7/30/2024: 6-2 PIT (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 7/29/2024: 5-3 PIT (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/12/2023: 7-0 HOU (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 4/11/2023: 7-4 PIT (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 4/10/2023: 8-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -188, Underdog Moneyline: +158)

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