Pirates vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for June 3

Odds updated as of 8:11 p.m.

On Wednesday in MLB, the Pittsburgh Pirates are up against the Houston Astros.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info regarding this game.

Pirates vs Astros Game Info

• Pittsburgh Pirates (33-28) vs. Houston Astros (27-35)
• Date: Wednesday, June 3, 2026
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and SportsNet PT

Pirates vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-146) | HOU: (+124)
• Spread: PIT: -1.5 (+114) | HOU: +1.5 (-137)
• Total: 7.5 -- Over: (-122) | Under: (+100)

Pirates vs Astros Probable Starting Pitchers

Probable Pitchers: Paul Skenes (Pirates) - 6-5, 2.89 ERA vs Spencer Arrighetti (Astros) - 7-1, 1.34 ERA

The probable starters are Paul Skenes (6-5) for the Pirates and Spencer Arrighetti (7-1) for the Astros. Skenes' team is 5-7-0 against the spread this season in his starts. When Skenes starts a game and his team is the favorite on the moneyline, they have a record of 6-5. When Arrighetti starts, the Astros have gone 7-1-0 against the spread. The Astros have a 6-1 record in Arrighetti's seven starts this season when they were the underdog on the moneyline.

Pirates vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (54.3%)

Pirates vs Astros Moneyline

• Looking at the moneyline for Astros-Pirates, Houston is the underdog at +124, and Pittsburgh is -146 playing on the road.

Pirates vs Astros Spread

• The Astros are +1.5 on the run line against the Pirates. The Astros are -137 to cover, and the Pirates are +114.

Pirates vs Astros Over/Under

• The over/under for Pirates-Astros on June 3 is 7.5. The over is -122, and the under is +100.

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Pirates vs Astros Betting Trends

• The Pirates have won in 22, or 61.1%, of the 36 contests they have been named as odds-on favorites in this year.
• This season Pittsburgh has been victorious seven times in 15 chances when named as a favorite of at least -146 on the moneyline.
• Contests with the Pirates have gone over the total set by sportsbooks in 33 of 60 chances this season.
• The Pirates have posted a record of 30-30-0 against the spread this season.
• The Astros have won 21 of the 44 games they were listed as the moneyline underdog this season (47.7%).
• Houston has gone 6-12 in games it has played as a moneyline underdog with odds of +124 or longer (33.3%).
• The Astros have played in 62 games with an over/under set, and have combined with their opponents to go over the total 34 times (34-26-2).
• The Astros have a 28-34-0 record against the spread this season (covering 45.2% of the time).

Pirates Player Leaders

• Bryan Reynolds leads Pittsburgh with an OBP of .403 this season while batting .272 with 44 walks and 39 runs scored. He has a slugging percentage of .432.
• He ranks 51st in batting average, sixth in on-base percentage, and 68th in slugging among qualified batters in MLB.
• Brandon Lowe leads Pittsburgh with 55 hits. He is batting .258 this season and has 28 extra-base hits. He's also slugging .535 with an on-base percentage of .343.
• Among qualifying hitters, his batting average ranks him 66th, his on-base percentage 65th, and his slugging percentage 10th.
• Lowe heads into this game looking to extend his three-game hit streak. In his last five games he is hitting .150 with a home run, a walk and four RBIs.
• Oneil Cruz has 62 hits this season and has a slash line of .258/.331/.475.
• Spencer Horwitz has been key for Pittsburgh with 50 hits, an OBP of .385 plus a slugging percentage of .458.

Astros Player Leaders

• Yordan Alvarez has put up an on-base percentage of .419, a slugging percentage of .645, and has 67 hits, all club-highs for the Astros (while batting .305).
• Including all qualified hitters in the majors, he is 12th in batting average, second in on-base percentage and second in slugging percentage.
• Christian Walker has 10 doubles, 16 home runs and 21 walks while hitting .248. He's slugging .504 with an on-base percentage of .321.
• Including all qualifying hitters, he is 87th in batting average, 99th in on-base percentage and 26th in slugging percentage.
• Isaac Paredes has 10 doubles, six home runs and 21 walks while hitting .233.
• Cam Smith has eight doubles, six home runs and 24 walks while hitting .216.

Pirates vs Astros Head to Head

• 6/2/2026: 10-6 PIT (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/4/2025: 3-0 PIT (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/3/2025: 3-0 HOU (Favorite: Pirates, Spread: -1.5, Total: 7, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 7/31/2024: 5-4 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 7/30/2024: 6-2 PIT (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 7/29/2024: 5-3 PIT (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/12/2023: 7-0 HOU (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 4/11/2023: 7-4 PIT (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 4/10/2023: 8-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -188, Underdog Moneyline: +158)

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