Phillies vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for June 6

Odds updated as of 3:11 p.m.

On Saturday in MLB, the Philadelphia Phillies are playing the Chicago White Sox.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Phillies vs White Sox Game Info

• Philadelphia Phillies (34-29) vs. Chicago White Sox (33-30)
• Date: Saturday, June 6, 2026
• Time: 4:05 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: NBCS-PH and CHSN

Phillies vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-134) | CHW: (+116)
• Spread: PHI: -1.5 (+138) | CHW: +1.5 (-166)
• Total: 9.5 -- Over: (-124) | Under: (+102)

Phillies vs White Sox Probable Starting Pitchers

Probable Pitchers: Andrew Painter (Phillies) - 1-6, 5.74 ERA vs Brandon Eisert (White Sox) - 1-0, 3.55 ERA

The Phillies will give the nod to Andrew Painter (1-6) versus the White Sox and Brandon Eisert (1-0). Painter's team is 1-9-0 against the spread in his starts this season. When Painter starts a game and his team is the favorite on the moneyline, they have a record of 3-1. Eisert has started only one game with a set spread, which the White Sox covered. The White Sox have always been the moneyline underdog when Eisert starts this season.

Phillies vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: White Sox win (50.8%)

Phillies vs White Sox Moneyline

• Looking at the moneyline for Phillies-White Sox, Philadelphia is the favorite at -134, and Chicago is +116 playing on the road.

Phillies vs White Sox Spread

• The White Sox are +1.5 on the run line against the Phillies. The White Sox are -166 to cover, and the Phillies are +138.

Phillies vs White Sox Over/Under

• The over/under for the Phillies versus White Sox game on June 6 has been set at 9.5, with -124 odds on the over and +102 odds on the under.

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Phillies vs White Sox Betting Trends

• The Phillies have won in 26, or 60.5%, of the 43 contests they have been named as odds-on favorites in this year.
• This season Philadelphia has been victorious 21 times in 35 chances when named as a favorite of at least -134 on the moneyline.
• The Phillies' games have gone over the total in 27 of their 62 opportunities.
• In 62 games with a line this season, the Phillies have a mark of 20-42-0 against the spread.
• The White Sox are 24-26 in games they were listed as the moneyline underdog (winning 48% of those games).
• Chicago has a 15-18 record (winning 45.5% of its games) when playing as a moneyline underdog of +116 or longer.
• The White Sox have played in 61 games with a set over/under, and have combined with their opponents to go over the total 35 times (35-25-1).
• The White Sox are 35-26-0 against the spread this season.

Phillies Player Leaders

• Bryce Harper has 58 hits this season and a team-best OBP of .369. He has a .265 batting average and a slugging percentage of .511.
• Among the qualified hitters in baseball, his batting average ranks 58th, his on-base percentage ranks 29th, and he is 23rd in slugging.
• Harper will look for his third straight game with a hit in this contest. In his last five games he is hitting .286 with a home run, five walks and two RBIs.
• Kyle Schwarber has 56 hits, which is tops among Philadelphia batters this season. He's batting .246 with 33 extra-base hits. He's also slugging .596 with an on-base percentage of .361.
• He is 94th in batting average, 37th in on-base percentage and third in slugging among qualifying hitters.
• Schwarber takes a three-game streak with at least one hit into this one. During his last five outings he is hitting .333 with a home run, five walks and an RBI.
• Brandon Marsh has hit six homers with a team-high .488 SLG this season.
• Marsh has picked up a hit in four games in a row. During his last five outings he is batting .421 with a home run, a walk and three RBIs.
• Trea Turner is batting .224 with a .275 OBP and 21 RBI for Philadelphia this season.

White Sox Player Leaders

• Miguel Vargas is hitting .243 with 10 doubles, a triple, 15 home runs and 42 walks. He's slugging .500 with an on-base percentage of .373.
• He ranks 98th in batting average, 26th in on-base percentage and 28th in slugging percentage among all qualified hitters in the big leagues.
• Vargas takes a four-game hitting streak into this game. In his last five games he is batting .316 with a double, two home runs, four walks and seven RBIs.
• Chase Meidroth is slugging .393 to pace his team. He has a batting average of .271 with an on-base percentage of .342.
• Including all qualified players, his batting average places him 51st, his on-base percentage is 65th, and he is 100th in slugging.
• Colson Montgomery has 11 doubles, 15 home runs and 22 walks while hitting .223.
• Sam Antonacci has eight doubles, two triples, a home run and 11 walks while hitting .286.

Phillies vs White Sox Head to Head

• 6/5/2026: 8-6 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 7/29/2025: 6-3 PHI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 7/28/2025: 6-2 CHW (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -240, Underdog Moneyline: +194)
• 4/21/2024: 8-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -290, Underdog Moneyline: +235)
• 4/20/2024: 9-5 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -375, Underdog Moneyline: +300)
• 4/19/2024: 7-0 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/19/2023: 5-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/18/2023: 3-0 CHW (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 4/18/2023: 7-4 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)

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