Phillies vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for June 3

Odds updated as of 1:11 a.m.

The Wednesday slate in MLB includes a matchup between the Philadelphia Phillies and the San Diego Padres.

All the info you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Phillies vs Padres Game Info

• Philadelphia Phillies (31-29) vs. San Diego Padres (32-27)
• Date: Wednesday, June 3, 2026
• Time: 6:40 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: NBCS-PH and Padres.TV

Phillies vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-210) | SD: (+176)
• Spread: PHI: -1.5 (-104) | SD: +1.5 (-115)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Phillies vs Padres Probable Starting Pitchers

Probable Pitchers: Cristopher Sanchez (Phillies) - 6-2, 1.47 ERA vs Walker Buehler (Padres) - 3-3, 4.88 ERA

The Phillies will give the nod to Cristopher Sanchez (6-2) against the Padres and Walker Buehler (3-3). Sanchez's team is 6-6-0 against the spread in his starts this season. When Sanchez starts a game and his team is the favorite on the moneyline, they have a record of 8-4. When Buehler starts, the Padres are 7-4-0 against the spread. The Padres are 4-2 in Buehler's six starts this season that they were the underdog on the moneyline.

Phillies vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (63.3%)

Phillies vs Padres Moneyline

• The moneyline numbers for Phillies vs. Padres reveal Philadelphia as the favorite (-210) and San Diego as the underdog (+176) on the road.

Phillies vs Padres Spread

• The Phillies are favored by 1.5 runs at home against the Padres. The Phillies are -104 to cover the spread, while the Padres are -115.

Phillies vs Padres Over/Under

• An over/under of 7.5 has been set for Phillies-Padres on June 3, with the over being -115 and the under -105.

Bet on Philadelphia Phillies vs. San Diego Padres on FanDuel today!

Phillies vs Padres Betting Trends

• The Phillies have been victorious in 23, or 57.5%, of the 40 contests they have been chosen as favorites in this season.
• This year Philadelphia has won four of five games when listed as at least -210 on the moneyline.
• The Phillies and their opponents have hit the over in 25 of their 59 games with a total set by oddsmakers this season.
• The Phillies have an against the spread record of 18-41-0 in 59 games with a line this season.
• The Padres have won 14 of the 27 games they were listed as the moneyline underdog this season (51.9%).
• San Diego has yet to play a game with moneyline odds of +176 or longer.
• The Padres have had an over/under set by oddsmakers 59 times, and have combined with opponents to go over the total in 24 of those games (24-34-1).
• The Padres have gone 33-26-0 ATS this season.

Phillies Player Leaders

• Bryce Harper has 55 hits this season and a team-best OBP of .363. He has a .262 batting average and a slugging percentage of .519.
• Among the qualifying hitters in the majors, his batting average ranks 60th, his on-base percentage ranks 36th, and he is 20th in slugging.
• Kyle Schwarber leads Philadelphia in total hits (50) this season while batting .231 with 32 extra-base hits. He's slugging .588 with an on-base percentage of .349.
• Among qualified hitters, he is 117th in batting average, 51st in on-base percentage and third in slugging percentage.
• Brandon Marsh leads Philadelphia in slugging percentage (.482) powered by 17 extra-base hits.
• Trea Turner has been key for Philadelphia with 55 hits, an OBP of .277 plus a slugging percentage of .351.
• Turner heads into this game on a three-game hitting streak. In his last five games he is hitting .250 with a home run and two RBIs.

Padres Player Leaders

• Xander Bogaerts is hitting .239 with three doubles, eight home runs and 22 walks. He's slugging .371 with an on-base percentage of .310.
• Including all qualified hitters, he ranks 99th in batting average, while his on-base percentage ranks 117th and he is 114th in slugging.
• Gavin Sheets' 41 hits lead his team. He has a batting average of .246 while slugging .485 with an on-base percentage of .333.
• He is 88th in batting average, 76th in on-base percentage and 31st in slugging percentage in MLB.
• Manny Machado is batting .171 with six doubles, 10 home runs and 27 walks.
• Fernando Tatis Jr.'s .347 OBP and .330 slugging percentage are both team-highs.

Phillies vs Padres Head to Head

• 6/2/2026: 3-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 5/27/2026: 3-0 PHI (Favorite: Phillies, Spread: -1.5, Total: 7, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 5/26/2026: 4-3 PHI (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/25/2026: 3-0 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 7/13/2025: 2-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/12/2025: 5-4 SD (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 7/11/2025: 4-2 SD (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 7/2/2025: 5-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/2/2025: 6-4 SD (Favorite: Padres, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/30/2025: 4-0 PHI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -250, Underdog Moneyline: +205)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!