Phillies vs Marlins Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 23

Odds updated as of 11:12 a.m.

The MLB schedule on Tuesday includes the Philadelphia Phillies facing the Miami Marlins.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Phillies vs Marlins Game Info

• Philadelphia Phillies (92-64) vs. Miami Marlins (76-80)
• Date: Tuesday, September 23, 2025
• Time: 6:45 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: NBCS-PH and FDSFL

Phillies vs Marlins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-220) | MIA: (+184)
• Spread: PHI: -1.5 (-106) | MIA: +1.5 (-113)
• Total: 8 -- Over: (-110) | Under: (-110)

Phillies vs Marlins Probable Starting Pitchers

Probable Pitchers: Cristopher Sanchez (Phillies) - 13-5, 2.66 ERA vs Edward Cabrera (Marlins) - 7-7, 3.57 ERA

The Phillies will give the nod to Cristopher Sanchez (13-5, 2.66 ERA), who is eyeing win No. 14 on the season, and the Marlins will turn to Edward Cabrera (7-7, 3.57 ERA). Sanchez and his team are 18-12-0 ATS this season when he starts. Sanchez's team is 20-6 this season when he starts and they are the moneyline favorite. When Cabrera starts, the Marlins have gone 16-8-0 against the spread. The Marlins have been the underdog on the moneyline in 19 of Cabrera's starts this season, and they went 10-9 in those games.

Phillies vs Marlins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (66.9%)

Phillies vs Marlins Moneyline

• Philadelphia is the favorite, -220 on the moneyline, while Miami is a +184 underdog on the road.

Phillies vs Marlins Spread

• The Phillies are hosting the Marlins and are favored by 1.5 runs (-106 to cover) on the runline. Miami is -113 to cover.

Phillies vs Marlins Over/Under

• The Phillies-Marlins contest on Sept. 23 has been given an over/under of 8 runs. The over is set at -110 and the under at -110.

Bet on Philadelphia Phillies vs. Miami Marlins on FanDuel today!

Phillies vs Marlins Betting Trends

• The Phillies have been victorious in 75, or 64.7%, of the 116 contests they have been chosen as favorites in this season.
• This season Philadelphia has come away with a win 14 times in 16 chances when named as a favorite of at least -220 on the moneyline.
• The Phillies and their opponents have gone over in 63 of their 149 games with a total set by sportsbooks this season.
• In 149 games with a line this season, the Phillies have a mark of 77-72-0 against the spread.
• The Marlins have put together a 59-63 record in games they were the underdog on the moneyline (winning 48.4% of those games).
• Miami is 7-10 (winning 41.2% of its games) when it has played as a moneyline underdog of +184 or longer.
• The Marlins have played in 151 games with an over/under set, and have combined with opponents to go over the total 75 times (75-75-1).
• The Marlins have collected an 87-64-0 record against the spread this season (covering 57.6% of the time).

Phillies Player Leaders

• Kyle Schwarber leads Philadelphia in OBP (.367) and total hits (140) this season. He's batting .241 batting average while slugging .559.
• Among qualifying batters in baseball, he is 108th in batting average, 13th in on-base percentage, and fourth in slugging.
• Bryce Harper has 32 doubles, 27 home runs and 68 walks. He's batting .263 and slugging .495 with an on-base percentage of .358.
• His batting average is 56th among qualified players, his on-base percentage 23rd, and his slugging percentage 17th.
• Bryson Stott has collected 123 base hits, an OBP of .331 and a slugging percentage of .391 this season.
• Stott takes a two-game hitting streak into this matchup. During his last five outings he is hitting .235 with two doubles and three walks.
• Nick Castellanos has been key for Philadelphia with 135 hits, an OBP of .298 plus a slugging percentage of .409.
• Castellanos has hit safely in three straight games. During his last five outings he is batting .235 with a home run, a walk and four RBIs.

Marlins Player Leaders

• Otto Lopez has 20 doubles, 15 home runs and 44 walks while hitting .248. He's slugging .373 with an on-base percentage of .309.
• Including all the qualifying hitters in the majors, he ranks 92nd in batting average, 110th in on-base percentage and 129th in slugging percentage.
• Lopez hopes to build on a four-game hitting streak in this matchup. In his last five games he is hitting .250 with two doubles, a home run and three RBIs.
• Agustin Ramirez's 121 hits pace his team. He has a batting average of .234 while slugging .424 with an on-base percentage of .291.
• His batting average is 125th among all qualified players, his on-base percentage is 131st, and he is 76th in slugging.
• Xavier Edwards has put up a team-best OBP (.338) and slugging percentage (.353).
• Eric Wagaman has 27 doubles, three triples, nine home runs and 32 walks while hitting .248.

Phillies vs Marlins Head to Head

• 9/7/2025: 5-4 MIA (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/6/2025: 4-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 9/5/2025: 9-3 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 6/19/2025: 2-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/18/2025: 4-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 6/16/2025: 5-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/20/2025: 7-5 MIA (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -310, Underdog Moneyline: +250)
• 4/19/2025: 11-10 PHI (Favorite: Phillies, Spread: -1.5, Total: 10.5, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 4/18/2025: 7-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 9/8/2024: 10-1 MIA (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!