Phillies vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for June 26

Odds updated as of 10:11 p.m.

On Thursday in MLB, the Philadelphia Phillies are up against the Houston Astros.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Phillies vs Astros Game Info

• Philadelphia Phillies (47-32) vs. Houston Astros (46-33)
• Date: Thursday, June 26, 2025
• Time: 2:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and NBCS-PH

Phillies vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-156) | HOU: (+132)
• Spread: PHI: -1.5 (+112) | HOU: +1.5 (-134)
• Total: 7.5 -- Over: (-104) | Under: (-118)

Phillies vs Astros Probable Starting Pitchers

Probable Pitchers: Cristopher Sanchez (Phillies) - 6-2, 2.77 ERA vs Hunter Brown (Astros) - 8-3, 1.88 ERA

This contest's pitching matchup is set, as the Phillies will send Cristopher Sanchez (6-2) to the mound, while Hunter Brown (8-3) will answer the bell for the Astros. Sanchez's team is 9-6-0 against the spread in his starts this season. Sanchez's team has been victorious in 84.6% of the games he's started as the moneyline favorite with a record of 11-2. The Astros have a 10-5-0 record against the spread in Brown's starts. The Astros have been the moneyline underdog in three of Brown's starts this season, and they went 2-1 in those games.

Phillies vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (57.4%)

Phillies vs Astros Moneyline

• Houston is the underdog, +132 on the moneyline, while Philadelphia is a -156 favorite despite being on the road.

Phillies vs Astros Spread

• The Astros are +1.5 on the run line against the Phillies. The Astros are -134 to cover, and the Phillies are +112.

Phillies vs Astros Over/Under

• Phillies versus Astros on June 26 has an over/under of 7.5 runs, with the odds on the over -104 and the under set at -118.

Bet on Philadelphia Phillies vs. Houston Astros on FanDuel today!

Phillies vs Astros Betting Trends

• The Phillies have been chosen as favorites in 61 games this year and have walked away with the win 41 times (67.2%) in those games.
• Philadelphia has a record of 27-7 in contests when oddsmakers favor them by -156 or more on the moneyline.
• Contests with the Phillies have gone over the total set by oddsmakers in 31 of 75 chances this season.
• The Phillies have posted a record of 38-37-0 against the spread this season.
• The Astros have been the underdog on the moneyline 23 total times this season. They've gone 13-10 in those games.
• Houston has a record of 2-1 when it has played as a moneyline underdog with odds of +132 or longer (66.7%).
• The Astros have played in 78 games with an over/under set, and have combined with opponents to go over the total 31 times (31-45-2).
• The Astros are 40-38-0 ATS this season.

Phillies Player Leaders

• Kyle Schwarber has 71 hits and an OBP of .378, both of which are best among Philadelphia hitters this season. He has a .247 batting average and a slugging percentage of .535.
• Among all qualifying hitters in the majors, he is 103rd in batting average, 18th in on-base percentage, and 13th in slugging.
• Trea Turner has hit nine homers this season while driving in 35 runs. He's batting .300 this season and slugging .448 with an on-base percentage of .355.
• He is 17th in batting average, 38th in on-base percentage and 59th in slugging among qualified hitters.
• Turner has picked up a hit in two straight games. During his last five outings he is batting .238 with a double and an RBI.
• Nick Castellanos has 85 hits this season and has a slash line of .285/.326/.443.
• Castellanos brings a four-game hitting streak into this game. During his last five outings he is hitting .350 with three doubles, a home run, a walk and five RBIs.
• Alec Bohm is batting .287 with a .327 OBP and 36 RBI for Philadelphia this season.

Astros Player Leaders

• Jeremy Pena has totaled 100 hits with a .382 on-base percentage and a .495 slugging percentage, all club-highs for the Astros. He's batting .326.
• Including all qualified hitters in the big leagues, he is fifth in batting average, 16th in on-base percentage and 24th in slugging percentage.
• Isaac Paredes is batting .254 with 10 doubles, a triple, 16 home runs and 42 walks. He's slugging .471 with an on-base percentage of .360.
• Including all qualified hitters, he ranks 87th in batting average, 33rd in on-base percentage and 41st in slugging percentage.
• Jose Altuve is batting .266 with 10 doubles, 12 home runs and 25 walks.
• Jake Meyers has 13 doubles, a triple, three home runs and 23 walks while batting .307.

Phillies vs Astros Head to Head

• 6/24/2025: 1-0 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/28/2024: 10-0 HOU (Favorite: Astros, Spread: -1.5, Total: 10, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/27/2024: 5-0 PHI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/26/2024: 3-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 4/30/2023: 4-3 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/29/2023: 6-1 PHI (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/28/2023: 3-1 PHI (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 11/5/2022: 4-1 HOU (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 11/3/2022: 3-2 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 11/2/2022: 5-0 HOU (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)

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