Pelicans vs. Cavaliers Prediction, Odds, Picks, Best Bets for March 21

Pelicans vs. Cavaliers Game Info

• Date: Saturday, March 21, 2026
• Time: 7 p.m. ET
• Venue: Smoothie King Center -- New Orleans, Louisiana
• Coverage: FDSOH, Gulf Coast Sports, and Pelicans+

The Cleveland Cavaliers (43-27) are favored (by 4.5 points) to extend a three-game road winning streak when they visit the New Orleans Pelicans (25-46) on Saturday, March 21, 2026 at 7 p.m. ET. The point total for the matchup is 236.5.

Pelicans vs. Cavaliers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Pelicans vs. Cavaliers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Cavaliers win (73.7%)

Pelicans vs. Cavaliers Betting Trends

• The Cavaliers have covered the spread in a matchup 29 times this season (29-40-1).
• The Pelicans are 41-28-1 against the spread this year.
• This season, 34 of the Cavaliers' games have gone over the point total out of 71 chances.
• Pelicans games this year have hit the over 49.3% of the time (35 out of 71 games with a set point total).
• Cleveland has covered the spread in a lower percentage of its home games than away games. It has covered 14 times in 35 games at home, and it has covered 15 times in 35 games on the road.
• When playing at home, the Cavaliers go over the over/under 37.1% of the time (13 of 35 games). They hit the over more consistently in road games, going over the total in 60% of games (21 of 35).
• New Orleans has performed better against the spread at home (24-13-0) than away (17-15-1) this year.
• Pelicans games have gone above the over/under more often at home (19 times out of 37) than away (16 of 34) this year.

Cavaliers Leaders

• Donovan Mitchell averages 28 points, 4.5 rebounds and 5.9 assists, shooting 47.9% from the floor and 36.4% from beyond the arc, with 3.3 made treys per contest (sixth in NBA).
• James Harden's numbers on the season are 24.2 points, 4.9 rebounds and 8 assists per game, shooting 43.3% from the floor and 37% from downtown, with an average of 3.1 made treys (ninth in NBA).
• Evan Mobley is averaging 18.3 points, 8.9 boards and 3.6 assists. Defensively, he averages 0.8 steals and 1.9 blocked shots (second in league).
• Jaylon Tyson averages 13.1 points, 5.1 boards and 2.2 assists, shooting 49.6% from the floor and 45.5% from beyond the arc (third in NBA), with 2 made 3-pointers per game.
• Dennis Schroder averages 11.4 points, 2.7 boards and 5 assists, shooting 40.4% from the floor and 33.6% from downtown, with 1.2 made treys per contest.

Pelicans Leaders

• Trey Murphy III's numbers on the season are 22 points, 5.7 rebounds and 3.9 assists per game. He is also sinking 47.3% of his shots from the floor and 38.6% from beyond the arc, with an average of 3.3 triples (sixth in league).
• The Pelicans are getting 17.4 points, 5.7 boards and 2.6 assists per game from Saddiq Bey.
• The Pelicans get 11.5 points per game from Derik Queen, plus 6.9 boards and 3.8 assists.
• The Pelicans receive 21.3 points per game from Zion Williamson, plus 5.8 boards and 3.3 assists.
• Jeremiah Fears averages 13 points, 3.6 rebounds and 3.2 assists. He is draining 42.8% of his shots from the field and 33.8% from 3-point range, with 1.1 triples per game.

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