Padres vs Mariners Prediction, Odds, Moneyline, Spread & Over/Under for May 17

Odds updated as of 8:12 p.m.

Saturday's slate in the MLB includes a matchup between the San Diego Padres and the Seattle Mariners.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Padres vs Mariners Game Info

• San Diego Padres (27-16) vs. Seattle Mariners (24-19)
• Date: Saturday, May 17, 2025
• Time: 8:40 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA and ROOT Sports NW

Padres vs Mariners Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-142) | SEA: (+120)
• Spread: SD: -1.5 (+164) | SEA: +1.5 (-200)
• Total: 7.5 -- Over: (-105) | Under: (-115)

Padres vs Mariners Probable Starting Pitchers

Probable Pitchers: Nick Pivetta (Padres) - 5-2, 3.05 ERA vs Emerson Hancock (Mariners) - 1-2, 6.91 ERA

The probable pitchers are Nick Pivetta (5-2) for the Padres and Emerson Hancock (1-2) for the Mariners. Pivetta's team is 6-2-0 against the spread this season in his starts. When Pivetta starts a game and his team is the favorite on the moneyline, they have a record of 2-1. The Mariners are 4-2-0 ATS in Hancock's six starts that had a set spread. The Mariners have been the moneyline underdog in four of Hancock's starts this season, and they went 3-1 in those games.

Padres vs Mariners Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (61.8%)

Padres vs Mariners Moneyline

• Seattle is the underdog, +120 on the moneyline, while San Diego is a -142 favorite at home.

Padres vs Mariners Spread

• The Padres are 1.5-run home favorites on the runline against the Mariners. The Padres are +164 to cover, and the Mariners are -200.

Padres vs Mariners Over/Under

• The over/under for Padres-Mariners on May 17 is 7.5. The over is -105, and the under is -115.

Bet on San Diego Padres vs. Seattle Mariners on FanDuel today!

Padres vs Mariners Betting Trends

• The Padres have come away with 16 wins in the 23 contests they have been listed as the favorites in this season.
• San Diego has a record of 12-5 in contests when sportsbooks favor them by -142 or more on the moneyline.
• The Padres' games have gone over the total in 19 of their 42 opportunities.
• The Padres have an against the spread record of 25-17-0 in 42 games with a line this season.
• The Mariners have been the underdog on the moneyline 17 total times this season. They've finished 9-8 in those games.
• Seattle has a 3-3 record (winning 50% of its games) when it has played as a moneyline underdog of +120 or longer.
• The Mariners have had an over/under set by bookmakers 43 times, and have combined with opponents to go over the total in 25 of those games (25-16-2).
• The Mariners have gone 21-22-0 ATS this season.

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego with 50 hits, batting .307 this season with 17 extra-base hits. He has an on-base percentage of .380 and a slugging percentage of .552.
• Among all qualified hitters in MLB, he is 15th in batting average, 26th in on-base percentage, and 11th in slugging.
• Manny Machado leads the Padres with an OPS of .879. He has a slash line of .331/.401/.478 this season.
• His batting average is fifth among qualified players, his on-base percentage eighth, and his slugging percentage 37th.
• Luis Arraez has collected 45 base hits, an OBP of .333 and a slugging percentage of .417 this season.
• Arraez has recorded at least one base hit in four straight games. In his last five games he is hitting .300 with a double.
• Xander Bogaerts is batting .238 with a .329 OBP and 20 RBI for San Diego this season.

Mariners Player Leaders

• Cal Raleigh has racked up 39 hits, a team-high for the Mariners. He's batting .250 and slugging .571 with an on-base percentage of .371.
• Including all qualifying hitters in the big leagues, he ranks 88th in batting average, 34th in on-base percentage and eighth in slugging percentage.
• Raleigh hopes to build on a four-game hitting streak in this matchup. In his last five games he is hitting .313 with a double, two home runs, three walks and five RBIs.
• Jorge Polanco has six doubles, 10 home runs and eight walks while hitting .324. He's slugging .649 with an on-base percentage of .372.
• Julio Rodriguez has a .408 slugging percentage, which leads the Mariners.
• J.P. Crawford paces his team with a .385 on-base percentage.

Padres vs Mariners Head to Head

• 5/16/2025: 5-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 9/11/2024: 5-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/10/2024: 7-3 SD (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/10/2024: 2-0 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/9/2024: 8-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/9/2023: 6-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/8/2023: 2-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/7/2023: 10-3 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/6/2023: 4-1 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/14/2022: 6-1 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -178, Underdog Moneyline: +150)

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