Padres vs Mariners Prediction, Odds, Moneyline, Spread & Over/Under for May 17

Odds updated as of 9:11 a.m.

The MLB schedule on Saturday includes the San Diego Padres facing the Seattle Mariners.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Padres vs Mariners Game Info

• San Diego Padres (27-16) vs. Seattle Mariners (24-19)
• Date: Saturday, May 17, 2025
• Time: 8:40 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA and ROOT Sports NW

Padres vs Mariners Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-184) | SEA: (+154)
• Spread: SD: -1.5 (+112) | SEA: +1.5 (-134)
• Total: 8 -- Over: (-118) | Under: (-104)

Padres vs Mariners Probable Starting Pitchers

Probable Pitchers: Nick Pivetta (Padres) - 5-2, 3.05 ERA vs Emerson Hancock (Mariners) - 1-2, 6.91 ERA

This contest's pitching matchup is set, as the Padres will send Nick Pivetta (5-2) to the mound, while Emerson Hancock (1-2) will answer the bell for the Mariners. Pivetta's team is 6-2-0 against the spread this season in his starts. Pivetta's team has been victorious in 66.7% of the games he's started as the moneyline favorite with a record of 2-1. The Mariners are 4-2-0 ATS in Hancock's six starts that had a set spread. The Mariners have been the underdog on the moneyline in four of Hancock's starts this season, and they went 3-1 in those matchups.

Padres vs Mariners Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (61.8%)

Padres vs Mariners Moneyline

• The moneyline numbers for Padres vs. Mariners reveal San Diego as the favorite (-184) and Seattle as the underdog (+154) on the road.

Padres vs Mariners Spread

• The Mariners are +1.5 on the spread (-134 to cover), and San Diego is +112 to cover the runline.

Padres vs Mariners Over/Under

• Padres versus Mariners on May 17 has an over/under of 8 runs, with the odds on the over -118 and the under set at -104.

Bet on San Diego Padres vs. Seattle Mariners on FanDuel today!

Padres vs Mariners Betting Trends

• The Padres have been victorious in 16, or 69.6%, of the 23 contests they have been chosen as favorites in this season.
• This season San Diego has been victorious six times in eight chances when named as a favorite of at least -184 on the moneyline.
• The Padres and their opponents have hit the over in 19 of their 42 games with a total set by oddsmakers this season.
• The Padres are 25-17-0 against the spread in their 42 games that had a posted line this season.
• The Mariners have won 52.9% of the games this season they were the underdog on the moneyline (9-8).
• Seattle has not yet played as a moneyline underdog of +154 or longer.
• The Mariners have had an over/under set by oddsmakers 43 times, and have combined with opponents to go over the total in 25 of those games (25-16-2).
• The Mariners have collected a 21-22-0 record ATS this season.

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego with 50 hits, batting .307 this season with 17 extra-base hits. He has an on-base percentage of .380 and a slugging percentage of .552.
• Among all qualifying hitters, he ranks 14th in batting average, his on-base percentage ranks 25th, and he is 11th in slugging.
• Manny Machado is slashing .331/.401/.478 this season and leads the Padres with an OPS of .879.
• Among qualified hitters, he ranks fifth in batting average, eighth in on-base percentage and 36th in slugging percentage.
• Luis Arraez has 45 hits this season and has a slash line of .298/.333/.417.
• Arraez takes a four-game hitting streak into this matchup. During his last five outings he is hitting .300 with a double.
• Xander Bogaerts is batting .238 with a .329 OBP and 20 RBI for San Diego this season.

Mariners Player Leaders

• Cal Raleigh has racked up 39 hits, a team-high for the Mariners. He's batting .250 and slugging .571 with an on-base percentage of .371.
• Including all qualifying hitters in the big leagues, he is 88th in batting average, 33rd in on-base percentage and seventh in slugging percentage.
• Raleigh enters this game on a four-game hitting streak. In his last five games he is hitting .313 with a double, two home runs, three walks and five RBIs.
• Jorge Polanco has six doubles, 10 home runs and eight walks while batting .324. He's slugging .649 with an on-base percentage of .372.
• Julio Rodriguez has a .408 slugging percentage, which paces the Mariners.
• J.P. Crawford paces his team with a .385 on-base percentage.

Padres vs Mariners Head to Head

• 5/16/2025: 5-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 9/11/2024: 5-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/10/2024: 7-3 SD (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/10/2024: 2-0 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/9/2024: 8-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/9/2023: 6-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/8/2023: 2-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/7/2023: 10-3 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/6/2023: 4-1 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/14/2022: 6-1 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -178, Underdog Moneyline: +150)

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