Padres vs Diamondbacks Prediction, Odds, Moneyline, Spread & Over/Under for April 26

Odds updated as of 3:11 p.m.

The Sunday schedule in MLB includes a matchup between the San Diego Padres and the Arizona Diamondbacks.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Padres vs Diamondbacks Game Info

• San Diego Padres (18-8) vs. Arizona Diamondbacks (14-12)
• Date: Sunday, April 26, 2026
• Time: 4:05 p.m. ET
• Venue: Estadio Alfredo Harp Helu -- Mexico City, Mexico
• Coverage: Dbacks.TV and Padres.TV

Padres vs Diamondbacks Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-134) | ARI: (+114)
• Spread: SD: -1.5 (+105) | ARI: +1.5 (-126)
• Total: 15 -- Over: (-110) | Under: (-110)

Padres vs Diamondbacks Probable Starting Pitchers

Probable Pitchers: Michael King (Padres) - 3-1, 2.28 ERA vs Ryne Nelson (Diamondbacks) - 1-2, 6.97 ERA

The Padres will give the ball to Michael King (3-1, 2.28 ERA), who is eyeing win No. 4 on the season, and the Diamondbacks will turn to Ryne Nelson (1-2, 6.97 ERA). King and his team have a record of 2-3-0 against the spread when he starts. King's team has been victorious in 66.7% of the games he's started as the moneyline favorite with a record of 2-1. When Nelson starts, the Diamondbacks are 2-3-0 against the spread. The Diamondbacks have a 1-4 record in Nelson's five starts this season when they were the moneyline underdog.

Padres vs Diamondbacks Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (52.6%)

Padres vs Diamondbacks Moneyline

• Looking at the moneyline for Padres-Diamondbacks, San Diego is the favorite at -134, and Arizona is +114 playing at home.

Padres vs Diamondbacks Spread

• The Padres are at the Diamondbacks and are favored by 1.5 runs on the spread. The Padres are +105 to cover the runline, with the Diamondbacks being -126.

Padres vs Diamondbacks Over/Under

• The over/under for the Padres versus Diamondbacks contest on April 26 has been set at 15, with -110 odds on the over and -110 odds on the under.

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Padres vs Diamondbacks Betting Trends

• The Padres have come away with nine wins in the 12 contests they have been listed as the favorites in this season.
• San Diego has a record of 8-1 in contests when bookmakers favor them by -134 or more on the moneyline.
• The Padres' games have gone over the total in 10 of their 26 opportunities.
• The Padres have an against the spread mark of 17-9-0 in 26 games with a line this season.
• The Diamondbacks have gone 7-9 in games they were the underdog on the moneyline (winning 43.8% of those games).
• Arizona is 6-4 (winning 60% of its games) when playing as a moneyline underdog of +114 or longer.
• In the 26 games bookmakers have set an over/under for the Diamondbacks, they have combined with opponents to go over the total 15 times (15-10-1).
• The Diamondbacks have an 18-8-0 record ATS this season.

Padres Player Leaders

• Xander Bogaerts leads San Diego with an OBP of .362, plus a team-best slugging percentage of .430. He's batting .280 on the season.
• Among the qualifying batters in the majors, his batting average ranks 41st, his on-base percentage ranks 42nd, and he is 68th in slugging.
• Ramon Laureano leads San Diego with 24 hits. He is batting .255 this season and has 10 extra-base hits. He's also slugging .468 with an on-base percentage of .314.
• He ranks 74th in batting average, 119th in on-base percentage and 47th in slugging in the majors.
• Jackson Merrill is batting .204 with a .357 slugging percentage and 14 RBI this year.
• Manny Machado has been key for San Diego with 17 hits, an OBP of .324 plus a slugging percentage of .291.
• Machado brings a three-game hitting streak into this game. In his last five games he is batting .200 with a walk and an RBI.

Diamondbacks Player Leaders

• Corbin Carroll has put up an on-base percentage of .400 and has 24 hits, both team-high figures for the Diamondbacks. He's batting .289 and slugging .566.
• Including all qualifying hitters, he is 30th in batting average, while his on-base percentage ranks 15th and he is 11th in slugging.
• Ildemaro Vargas leads his team with a .649 slugging percentage. He has a batting average of .351 with an on-base percentage of .368.
• Geraldo Perdomo has three doubles, three triples, a home run and 14 walks while hitting .250.
• Ketel Marte is batting .240 with three doubles, four home runs and nine walks.

Padres vs Diamondbacks Head to Head

• 4/25/2026: 6-4 SD (Favorite: Diamondbacks, Spread: -1.5, Total: 16, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/28/2025: 12-4 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/27/2025: 5-1 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 9/26/2025: 7-4 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/6/2025: 3-2 SD (Favorite: Padres, Spread: -1.5, Total: 9.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/5/2025: 10-5 SD (Favorite: Padres, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/4/2025: 6-2 ARI (Favorite: Padres, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/10/2025: 4-3 SD (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/9/2025: 8-2 ARI (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 7/8/2025: 1-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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