Padres vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 7

Odds updated as of 6:12 a.m.

The San Diego Padres versus the Houston Astros is on the MLB schedule for Friday.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Padres vs Astros Game Info

• San Diego Padres (60-56) vs. Houston Astros (59-57)
• Date: Friday, August 7, 2026
• Time: 9:40 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Padres.TV and SCHN

Padres vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-120) | HOU: (+102)
• Spread: SD: +1.5 (-205) | HOU: -1.5 (+168)
• Total: 8.5 -- Over: (+104) | Under: (-128)

Padres vs Astros Probable Starting Pitchers

Probable Pitchers: Robbie Ray (Padres) - 10-6, 3.08 ERA vs Ronel Blanco (Astros) - 0-1, 7.36 ERA

This contest's pitching matchup is set, as the Padres will send Robbie Ray (10-6) to the mound, while Ronel Blanco (0-1) will get the nod for the Astros. Ray and his team have a record of 11-8-0 against the spread when he starts. When Ray starts a game and his team is the favorite on the moneyline, they have a record of 6-2. The Astros have a 2-1-0 record against the spread in Blanco's starts. The Astros were the moneyline underdog for two Blanco starts this season -- they split the games.

Padres vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (55.3%)

Padres vs Astros Moneyline

• Houston is a +102 underdog on the moneyline, while San Diego is a -120 favorite at home.

Padres vs Astros Spread

• The Astros are 1.5-run favorites against the spread for this matchup with the Padres. The Astros are +168 to cover, while the Padres are -205 to cover as a 1.5-run underdog on the runline.

Padres vs Astros Over/Under

• The over/under for Padres-Astros on Aug. 7 is 8.5. The over is +104, and the under is -128.

Bet on San Diego Padres vs. Houston Astros on FanDuel today!

Padres vs Astros Betting Trends

• The Padres have won in 26, or 54.2%, of the 48 contests they have been named as odds-on favorites in this year.
• San Diego has a record of 22-17 in contests when oddsmakers favor them by -120 or more on the moneyline.
• The Padres and their opponents have gone over in 53 of their 116 games with a total set by sportsbooks this season.
• The Padres are 64-52-0 against the spread in their 116 games that had a posted line this season.
• The Astros have been the moneyline underdog 65 total times this season. They've finished 34-31 in those games.
• When it has played as a moneyline underdog with odds of +102 or longer, Houston has a 26-22 record (winning 54.2% of its games).
• The Astros have had an over/under set by bookmakers 116 times, and have combined with opponents to go over the total in 63 of those games (63-49-4).
• The Astros have put together a 58-58-0 record ATS this season (covering 50% of the time).

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego with an OBP of .350, plus a team-best slugging percentage of .403. He's batting .280 on the season.
• Among qualifying hitters in MLB, he is 32nd in batting average, 48th in on-base percentage, and 97th in slugging.
• Tatis hopes to build on a three-game hitting streak in this matchup. During his last five outings he is batting .150 with two doubles, a home run, two walks and an RBI.
• Manny Machado has 88 hits, which ranks first among San Diego batters this season. He's batting .210 with 43 extra-base hits. He's also slugging .422 with an on-base percentage of .294.
• His batting average is 142nd among qualified players, his on-base percentage 131st, and his slugging percentage 75th.
• Jackson Merrill has collected 106 base hits, an OBP of .292 and a slugging percentage of .396 this season.
• Xander Bogaerts is batting .227 with a .323 OBP and 41 RBI for San Diego this season.

Astros Player Leaders

• Yordan Alvarez has totaled 136 hits with a .442 on-base percentage and a .640 slugging percentage, all club-bests for the Astros. He's batting .329.
• Including all qualifying players in the big leagues, he is first in batting average, first in on-base percentage and first in slugging percentage.
• Alvarez hopes to build on a six-game hitting streak in this matchup. During his last 10 games he is batting .371 with four doubles, a home run, 13 walks and eight RBIs.
• Isaac Paredes has 18 doubles, a triple, 15 home runs and 45 walks while hitting .249. He's slugging .412 with an on-base percentage of .346.
• He is currently 85th in batting average, 53rd in on-base percentage and 87th in slugging percentage among all qualified hitters.
• Christian Walker is hitting .240 with 24 doubles, a triple, 22 home runs and 38 walks.
• Jeremy Pena is hitting .311 with 12 doubles, a triple, 13 home runs and 20 walks.

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